Results 31 to 40 of about 1,087,915 (317)

Tumor-associated macrophages modulate resistance to oxaliplatin via inducing autophagy in hepatocellular carcinoma

Cancer Cell International, 2019
Background Oxaliplatin-based chemotherapy is widely used to treat hepatocellular carcinoma (HCC). Recent studies suggested that therapeutic resistance of tumors was affected by tumor microenvironment (TME).
Xiu-Tao Fu, Kang Song, Jian Zhou, Ying-Hong Shi, Wei-Ren Liu, Guo-Ming Shi, Qiang Gao, Xiao-Ying Wang, Zhen-Bin Ding, Jia Fan   +9 more
doaj   +1 more source

Serial circulating tumor DNA to predict early recurrence in patients with hepatocellular carcinoma: a prospective study

Molecular Oncology, 2022
We studied the value of circulating tumor DNA (ctDNA) in predicting early postoperative tumor recurrence and monitoring tumor burden in patients with hepatocellular carcinoma (HCC).
Gui‐Qi Zhu, Wei‐Ren Liu, Zheng Tang, Wei‐Feng Qu, Yuan Fang, Xi‐Fei Jiang, Shu‐Shu Song, Han Wang, Chen‐Yang Tao, Pei‐Yun Zhou, Run Huang, Jun Gao, Hai‐Xiang Sun, Zhen‐Bin Ding, Yuan‐Fei Peng, Zhi Dai, Jian Zhou, Jia Fan, Ying‐Hong Shi   +18 more
doaj   +1 more source

Evolving trends in treatment patterns for hepatocellular carcinoma in Korea from 2008 to 2022: a nationwide population-based study [PDF]

Journal of Liver Cancer
Backgrounds/Aims The treatment landscape for hepatocellular carcinoma (HCC) has significantly evolved over the past decade. We aimed to analyze trends in treatment patterns for HCC using a nationwide claims database from the Korean Health Insurance ...
Ji Won Han, Won Sohn, Gwang Hyeon Choi, Jeong Won Jang, Gi Hyeon Seo, Bo Hyun Kim, Jong Young Choi   +6 more
doaj   +1 more source

Programmed cell death 10 promotes metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma via PP2Ac-mediated YAP activation

Cell Death and Disease, 2021
Tumour metastasis is the main cause of postoperative tumour recurrence and mortality in patients with hepatocellular carcinoma (HCC), but the underlying mechanism remains unclear.
Bo Sun, Fang-Jing Zhong, Cong Xu, Yi-Ming Li, Yan-Rong Zhao, Mo-Mo Cao, Lian-Yue Yang   +6 more
doaj   +1 more source

Cancer cell-derived exosomal circUHRF1 induces natural killer cell exhaustion and may cause resistance to anti-PD1 therapy in hepatocellular carcinoma

Molecular Cancer, 2020
Objective Natural killer (NK) cells play a critical role in the innate antitumor immune response. Recently, NK cell dysfunction has been verified in various malignant tumors, including hepatocellular carcinoma (HCC).
Peng-Fei Zhang, Chao Gao, Xiao-Yong Huang, Jia-Cheng Lu, Xiao-Jun Guo, Guo-Ming Shi, Jia-Bin Cai, Ai-Wu Ke   +7 more
doaj   +1 more source

Laparoscopic vs. Open Repeat Hepatectomy for Recurrent Liver Tumors: A Propensity Score–Matched Study and Meta-Analysis

Frontiers in Oncology, 2021
Background: It remains unclear whether the short-term benefits of laparoscopic repeat hepatectomy (LRH) accrue to patients with recurrent liver tumors. The present study aimed to report our own center's experience and perform a meta-analysis to evaluate ...
Jia-Feng Chen, Xiu-Tao Fu, Zheng Gao, Ying-Hong Shi, Zheng Tang, Wei-Ren Liu, Xin Zhang, Qiang Gao, Guang-Yu Ding, Kang Song, Xiao-Ying Wang, Jian Zhou, Jian Zhou, Jia Fan, Jia Fan, Zhen-Bin Ding   +15 more
doaj   +1 more source

The utility of liver function tests for mortality prediction within one year in primary care using the algorithm for liver function investigations (ALFI) [PDF]

, 2012
BACKGROUND: Although liver function tests (LFTs) are routinely measured in primary care, raised levels in patients with no obvious liver disease may trigger a range of subsequent expensive and unnecessary management plans.
Roderick Paul, Donnan, Peter T, John F. Dillon (110507), Stephen D Ryder, McLernon, DJ, Rosenberg, WM, McLernon, D.J., McLernon David J., Roderick, P., William M. Rosenberg (110512), Roderick, Paul, Donnan, PT, Dillon, John F.; id_orcid, McLernon, David J., David J McLernon, Rosenberg, William M, Paul Roderick, Donnan, Peter T.; id_orcid, Sullivan, F.M., Dillon, J.F., Ryder, Stephen D., Sullivan, Frank M, Ryder, S.D., McLernon, David J, Rosenberg, William M., Dillon, John F., John F Dillon, Peter T. Donnan (110517), Donnan, Peter T., Roderick, P, Paul Roderick (14856), Donnan, P.T., Sullivan, FM, Ryder Stephen D., Sullivan Frank M., David J. McLernon (110505), Donnan Peter T., Peter T Donnan, Dillon, John F, Rosenberg, W.M., Frank M Sullivan, Rosenberg William M., Ryder, SD, Dillon, JF, Frank M. Sullivan (110508), William M Rosenberg, Sullivan, Frank M., Ryder, Stephen D, Dillon John F., Stephen D. Ryder (110515)   +49 more
core   +1 more source

Expert consensus on precision detection of intrahepatic cholangiocarcinoma (2024 edition)

Zhongguo Linchuang Yixue
Intrahepatic cholangiocarcinoma (ICC) is a highly heterogeneous tumor, and molecular profiling serves as the foundation for personalized treatment of ICC.
Pathology Group, Chinese Society of Liver Cancer of Chinese Anti-Cancer Association; Liver Pathology Group, Chinese Society of Pathology of Chinese Anti-Cancer Association; Tumor Pathology Committee of Shanghai Anti-Cancer Association, Shanghai 200032, China
doaj   +1 more source

PCSK9 promotes tumor growth by inhibiting tumor cell apoptosis in hepatocellular carcinoma

Experimental Hematology & Oncology, 2021
Background Proprotein convertase subtilisin/kexin type 9 (PCSK9), one of the key enzymes in the process of lipid transport, is involved in the disease progression of various types of tumors.
Shi-Zhe Zhang, Xiao-Dong Zhu, Long-Hai Feng, Xiao-Long Li, Xue-Feng Liu, Hui-Chuan Sun, Zhao-You Tang   +6 more
doaj   +1 more source

Next-Generation Sequencing: Application in Liver Cancer—Past, Present and Future?

, 2012
Hepatocellular Carcinoma (HCC) is the third most deadly malignancy worldwide characterized by phenotypic and molecular heterogeneity. In the past two decades, advances in genomic analyses have formed a comprehensive understanding of different underlying ...
Marquardt, Jens U, Andersen, Jesper B, Jesper B. Andersen, Jens U. Marquardt   +3 more
core   +1 more source