Results 11 to 20 of about 4,753,656 (310)
Gut and Liver, 2019 Hepatocellular carcinoma (HCC) is the fifth most common cancer globally and the fourth most common cancer in men in Korea, where the prevalence of chronic hepatitis B infection is high in middle-aged and elderly patients.
KLCA Korean Liver Cancer Association +1 more
doaj +2 more sources
Liver Transplantation for Pediatric Liver Cancer [PDF]
Cancers, 2020 Unresectable hepatocellular carcinoma (HCC) was first removed successfully with total hepatectomy and liver transplantation (LT) in a child over five decades ago. Since then, children with unresectable liver cancer have benefitted greatly from LT and a confluence of several equally important endeavors. Regional and trans-continental collaborations have
Rakesh Sindhi +6 more
openaire +2 more sources
Autophagy and liver cancer [PDF]
Clinical and Molecular Hepatology, 2020 Autophagy is a highly conserved catabolic process that degrades cytosolic proteins and organelles via formation of autophagosomes that fuse with lysosomes to form autolysosomes, whereby autophagic cargos are degraded. Numerous studies have demonstrated that autophagy plays a critical role in the regulation of liver physiology and homeostasis, and ...
Xiaojuan Chao +4 more
openaire +3 more sources
Autophagy and liver cancer [PDF]
Turkish Journal of Gastroenterology, 2018 Abstract Autophagy is a key biological phenomenon conserved from yeast to mammals. Under basal conditions, activation of autophagy leads to the protein degradation as well as damaged organelles for maintaining cellular homeostasis. Deregulation of autophagy has been identified as a key mechanism contributing to the pathogenesis and progression of ...
Akkoç, Yunus, Gözüaçık, Devrim
openaire +5 more sources
Immune mediated and direct killing of colorectal cancer by reovirus [PDF]
, 2012 Colorectal cancer remains the second most prevalent cancer in the world. Novel treatment strategies are necessary, especially for the treatment of metastatic disease.
Adair, Robert Allan
core +6 more sources
Journal of Translational Medicine, 2020 Background The genomic alterations of intrahepatic cholangiocarcinoma (ICC) in the Chinese population have not been fully revealed. Molecular profiling may provide a reference for clinical management, especially targeted therapy.
Longrong Wang +15 more
doaj +1 more source
Cell Death and Disease, 2023 Multidrug resistance is a major challenge in treating advanced hepatocellular carcinoma (HCC). Although recent studies have reported that the multidrug resistance phenotype is associated with abnormal DNA methylation in cancer cells, the epigenetic ...
Xiao-Jun Guo +17 more
doaj +1 more source
BMC Cancer, 2020 Background The prognosis of patients with combined hepatocellular carcinoma and intrahepatic cholangiocarcinoma (CHC) is usually poor, and effective adjuvant therapy is missing making it important to investigate whether these patients may benefit from ...
Wei-Ren Liu +14 more
doaj +1 more source
Cancer Cell International, 2020 Background Plasmacytoid dendritic cells (pDCs) are present in various primary and metastatic human neoplasms; however, their clinical significance in intrahepatic cholangiocarcinoma is not clear.
Zhi-Qiang Hu +6 more
doaj +1 more source
Small Molecule‐Induced Differentiation As a Potential Therapy for Liver Cancer
Advanced Science, 2022 Despite the efficacy demonstrated by immunotherapy recently, liver cancer still remains one of the deadliest cancers, mainly due to heterogeneity of this disease. Continuous exploration of new therapeutics is therefore necessary.
Xu Zhang +9 more
doaj +1 more source