Results 101 to 110 of about 73,718 (217)

LSECtin attenuates hepatic Th17 expansion in a murine model of cirrhosis and signals through the LAG-3 receptor

JHEP Reports
Background & Aims: LSECtin downregulation during cirrhosis progression is associated with adaptive T-cell expansion. We analyzed the molecular mechanism for LSECtin modulation of Th17 proliferation in an experimental cirrhosis model.
Sebastián Martínez-López, Oriol Juanola, Isabel Gómez-Hurtado, Enrique Ángel-Gomis, Paula Boix, Anabel Fernández-Iglesias, Alex Gallardo-Cruz, Francisco Javier Cubero, Jordi Gracia-Sancho, Amaya Puig-Kröger, Esther Caparrós, Rubén Francés   +11 more
doaj   +1 more source

Regression of fibrosis and portal hypertension in chronic liver disease: Endothelial perspectives and clinical implications

Annals of Hepatology
Chronic liver disease (CLD) remains a major global health burden, driven by persistent hepatic injury that triggers inflammation, vascular dysfunction and progressive extracellular matrix (ECM) deposition.
Yuly P Mendoza, Raül Pastó, Sonia E Selicean, Jordi Gracia-Sancho   +3 more
doaj   +1 more source

Model for End‐Stage Liver Disease/Pediatric End‐Stage Liver Disease exception policy and outcomes in pediatric patients with hepatopulmonary syndrome requiring liver transplantation

Liver Transplantation, EarlyView., 2022
Abstract Hepatopulmonary syndrome (HPS) is associated with increased waitlist mortality in liver transplantation (LT) candidates. Children with HPS are granted Model for End‐Stage Liver Disease (MELD)/Pediatric End‐Stage Liver Disease (PELD) exception points for waitlist prioritization in the United States based on criterion developed for adults.
Muhammad H. Raza, Yong Kwon, Pierre Kobierski, Asish C. Misra, Angelina Lim, Cameron Goldbeck, Kambiz Etesami, Rohit Kohli, Juliet Emamaullee   +8 more
wiley   +1 more source

Availability of Cancer Screening Across HIV Treatment Sites in the IeDEA Consortium

International Journal of Cancer, EarlyView.
In recent years, incorporating comprehensive cancer screening strategies into routine HIV care has gained growing attention. This survey of 220 sites providing HIV care across 41 countries shows that cervical cancer screening has increased in availability over time.
Rachael A. Pellegrino, Bryan E. Shepherd, Sanjay Pujari, Valeria Fink, Gad Murenzi, Miriam Nakalembe, Sally B. Coburn, Eliane Rohner, Antoine Jaquet, Caroline Lade, Brenda Crabtree Ramirez, Kathryn Anastos, Aggrey Semeere, Lesley S. Park, Limpho Mokone, Simon Boni, I Ketut Agus Somia, Emilia M. Jalil, Adebola Adedimeji, Omenge Orang'o, Michael J. Silverberg, Kumbirai Pise Quarter, Eugène Messou, Jeremy Ross, Eduardo Gotuzzo, Patricia Lelo, Helen Byakwaga, Oliver Ezechi, Jonathan Euvrard, Fernanda Maruri, Chad J. Achenbach, Jessica L. Castilho, on behalf of International epidemiology Databases to Evaluate AIDS (IeDEA)   +32 more
wiley   +1 more source

Acute HEV Infection Is a Relevant Cause of Decompensation and ACLF in Patients With Liver Cirrhosis. [PDF]

Liver Int
Dinkelborg K, Niehaus C, Bremer B, Wundes C, Tiede A, Petruch N, Deterding K, Kraft ARM, Hartleben B, Cornberg M, Wedemeyer H, Behrendt P, Maasoumy B.   +12 more
europepmc   +1 more source

New‐Onset Type 2 Diabetes Mellitus and Cancer Risk: A Matched Cohort Study in China Kadoorie Biobank

International Journal of Cancer, EarlyView.
ABSTRACT The prevalence of type 2 diabetes mellitus (T2DM) is rising rapidly in China and is linked to increased cancer risk, but causality remains unclear due to biases. We examined the causal effect of T2DM on cancer risk using bias‐minimizing methods.
Mengying Wang, Owen Tipping, Bowen Liu, Derrick A. Bennett, Baiyong Shen, Siyi Zou, Shulin Zhao, Richard M. Martin, Matthew Sperrin, Andrew G. Renehan   +9 more
wiley   +1 more source

The Gastrointestinal Barrier-Mechanisms of Barrier Dysfunction in Liver Cirrhosis and Spontaneous Bacterial Peritonitis. [PDF]

Biomedicines
Olaru-Stavila C, Steinmann SM, Mester P, Müller M, Tcaciuc E, Gülow K.   +5 more
europepmc   +1 more source

Surgically confirmed severe endometriosis is associated with lower risk of steatotic liver disease: Evidence of estrogen‐linked hepatic–reproductive crosstalk

International Journal of Gynecology &Obstetrics, EarlyView.
Severe surgically confirmed endometriosis was associated with a lower prevalence of steatotic liver disease than non‐severe disease. Higher estradiol levels may partly explain this inverse hepatic–reproductive association, supporting integrated gynecologic and hepatologic risk assessment.
Jung Hyun Park, Keungmo Yang, Hyun Yang, Si Hyun Bae, Mee‐Ran Kim, Jaejun Lee   +5 more
wiley   +1 more source

Epigenetic drug control of Clec4g/LSECtin expression reduces fibrosis burden in cirrhosis. [PDF]

Hepatol Commun
Ángel-Gomis E, Gómez-Hurtado I, Fernández-Barrena MG, Juanola O, Martínez-López S, Boix P, Ávila MA, Caparrós E, Francés R.   +8 more
europepmc   +1 more source

Patient reported outcomes and results of endometrial balloon ablation for the treatment of heavy menstrual bleeding: A single center observational cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Heavy menstrual bleeding is one of the most common gynecologic disorders among women of reproductive age and has a significant impact on their physical, psychological, and social well‐being. Although international guidelines recommend medical therapy as the first‐line treatment, it may prove ineffective, poorly tolerated, or ...
Jonas Rudaitis, Patricija Marozaite, Egle Bareikiene, Vilius Rudaitis   +3 more
wiley   +1 more source