Results 121 to 130 of about 73,718 (217)

Gut dysbiosis and nitric oxide dysregulation in cirrhosis progression: mechanistic insights and pathophysiological implications. [PDF]

J Physiol Biochem
Răzniceanu V, Țichindeleanu A, Răducu EV, Trella ȘE, Nenu I.   +4 more
europepmc   +1 more source

Mode‐of‐Action and Human Relevance Assessment for Diisononyl Phthalate‐Induced Liver Tumors in Rodents

Journal of Applied Toxicology, EarlyView.
ABSTRACT Diisononyl phthalate (DINP) is a high molecular weight phthalate and high production volume chemical. DINP's carcinogenic potential has been investigated in four rodent bioassays, with liver tumors observed in three of the studies. Authoritative assessments have hypothesized that DINP acts through the peroxisome proliferator‐activated receptor
Amanda N. Buerger, Melissa M. Heintz, Laurie C. Haws, Chad M. Thompson   +3 more
wiley   +1 more source

Sarcopenia Predicts Mortality and Hepatic Encephalopathy After TIPS in Older Adults With Cirrhosis and Improves Prognostic Scores. [PDF]

Liver Int
Saltini D, Nardelli S, Miraglia R, Roccarina D, Gioia S, Banchelli F, Maruzzelli L, Caporali C, Falcone G, Bianchini M, Guasconi T, Ingravallo A, Di Cola S, Critelli RM, Milosa F, Piscopo A, Casari F, Mayorga ASV, Scianò F, Battinelli G, Ascari F, Riggio O, Marra F, Merli M, Vizzutti F, Schepis F.   +25 more
europepmc   +1 more source

Biochemical and Molecular Insights Into Monocrotaline‐Induced Hepatotoxicity: An Experimental Mouse Study

Journal of Applied Toxicology, EarlyView.
ABSTRACT Monocrotaline (MCT), a plant‐derived pyrrolizidine alkaloid, is well known for its hepatotoxic effects. However, full elucidation of the mechanisms underlying MCT‐induced hepatotoxicity, as well as the development of reliable biomarkers for early detection and monitoring, requires an integrated evaluation of biochemical, molecular, and ...
Ali Şenol, Alparslan Kadir Devrim, Miyase Çinar, Mahmut Sözmen, Fatma Betül Akça   +4 more
wiley   +1 more source

Fecal microbiota transplant and its usefulness in hepatic disorders: a systematic review. [PDF]

Ther Adv Gastroenterol
Mishra AK, Mishra A, Vikal A, Singh H, Y Thajudeen K, Khan G, Ahmed MM.   +6 more
europepmc   +1 more source

Soluble B7‐H6 as a Novel Diagnostic Biomarker for Post‐Hepatitis B Cirrhosis: A Clinical Value Study

Journal of Clinical Laboratory Analysis, EarlyView.
This study investigates the potential of soluble B7‐H6 (sB7‐H6) as a novel diagnostic biomarker for post‐hepatitis B cirrhosis. The infographic visually presents the following key points: (1) Liver Disease Progression: Chronic hepatitis B (CHB) progresses to liver cirrhosis (LC), with serum sB7‐H6 levels increasing stepwise as the disease advances. (2)
Kaiyong Chen, Luxuan Yang, Huaiwu Fu, Lei Cao, Zhu Li   +4 more
wiley   +1 more source

Liver fibrosis severity evaluated by shear-wave elastography is associated with procoagulant and systemic inflammatory activity in patients with cirrhosis. [PDF]

Ann Gastroenterol
Kalambokis G, Aggelis N, Tsiakas I, Biros D, Despotis G, Papapetrou E, Tsaousi C, Markopoulos GS, Kolios G, Konstantopoulou R, Tsiara S, Baltayiannis G, Milionis H.   +12 more
europepmc   +1 more source

Changes of CEA Diagnostic Performance Under the New Reference Interval Stratified by Age and Sex

Journal of Clinical Laboratory Analysis, EarlyView.
Our study included patients with lung cancer, breast cancer, and colorectal cancer and apparently healthy individuals, conducted a large case–control study to assess the effects of age and sex on serum concentrations and positive rates of CEA, established age‐ and sex‐stratified reference intervals using indirect methods.
Ke Zhang, Xiarui Ye
wiley   +1 more source

Metabotropic Glutamate Receptor 3 Expression During Liver Disease Progression: Association with Inflammation and Cell Viability in Hepatocellular Carcinoma. [PDF]

Int J Mol Sci
García-Gaytán AC, Hernández-Abrego A, De Ita-Pérez D, de Los Ríos-Arellano E, Gámez E, Díaz-Muñoz M, Méndez I.   +6 more
europepmc   +1 more source

A Comprehensive Study of Bidirectional Interactions Between the Human Microbiome and Blood Malignancies and Hematologic Conditions: Focus on Novel Therapeutic Strategies

Journal of Clinical Laboratory Analysis, EarlyView.
Microbiota‐targeted therapeutic strategies in hematological disorders. aHSCT: Transplanted immune cells from the donor may attack the recipient's tissues, especially when damage to the intestinal epithelium disrupts the gut microbiota, contributing to GVHD. Maintaining a balanced gut microbiota that supports immune regulation helps reduce GVHD risk and
Alireza Molajafari, Hadi Sedigh Ebrahim‐Saraie, Majid Taati Moghadam, Meysam Hasannejad‐Bibalan   +3 more
wiley   +1 more source