Results 121 to 130 of about 239,171 (312)
IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases Abstract Background and Aims Pruritus is associated with multiple liver diseases, particularly those with cholestasis, but the mechanism remains incompletely understood.
Jun Xu+20 more
wiley +1 more source
Purpose Hepatocellular carcinoma (HCC) has a poor prognosis, and alpha-fetoprotein (AFP) is widely used to evaluate HCC. However, the proportion of AFP-negative individuals cannot be disregarded.
Chengyu Liu+12 more
doaj +1 more source
Nonlinear association structures in flexible Bayesian additive joint models [PDF]
Joint models of longitudinal and survival data have become an important tool for modeling associations between longitudinal biomarkers and event processes. The association between marker and log-hazard is assumed to be linear in existing shared random effects models, with this assumption usually remaining unchecked.
arxiv
Recent advances of nanomaterials in imaging liver fibrosis
Schematic summary on the latest strategies of liver fibrosis imaging based on various nanomaterials. Abstract Liver fibrosis is a pathological process resulting from prolonged exposure to various injury factors. It is characterized by the abnormal proliferation and activation of hepatic stellate cells and excessive deposition of extracellular matrix ...
Jin Cui+11 more
wiley +1 more source
Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis
EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu+16 more
wiley +1 more source
URINARY EXCRETION OF AMINO ACIDS IN PATIENTS WITH CIRRHOSIS OF THE LIVER AND IN NORMAL ADULTS 12 [PDF]
George J. Gabuzda+2 more
openalex +1 more source
Cirrhosis of the Liver in Childhood [PDF]
n ...
openaire +3 more sources
Liver organoids: From 3D printing to biomedical applications
A comprehensive review on liver organoids culture techniques from 3D printing to organ‐on‐chip, as well as focusing on challenges and perspectives for advancement liver organoids in various future applications. Abstract The liver is an immune organ, especially an immune tolerance organ.
Ying Shi+4 more
wiley +1 more source
Abstract Background and Aims Reliable noninvasive biomarkers are an unmet clinical need for the diagnosis of NASH. This study investigates the diagnostic accuracy of the circulating triggering receptor expressed on myeloid cells 2 (plasma TREM2) as a biomarker for NASH in patients with NAFLD and elevated liver stiffness.
Vineesh Indira Chandran+17 more
wiley +1 more source