Results 161 to 170 of about 2,061,642 (403)
Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis
EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu+16 more
wiley +1 more source
Liver transplantation in primary biliary cirrhosis: Risk assessment and 11-year follow-up [PDF]
Background/Aims: Liver transplantation (LTx) is the only established treatment in patients with end-stage primary biliary cirrhosis (PBC). Although short-term survival after LTx in this group of patients is usually good, few data exist on the long-term ...
Beuers, Ulrich+8 more
core +2 more sources
TOTAL EXCHANGEABLE SODIUM, TOTAL EXCHANGEABLE POTASSIUM, AND TOTAL BODY WATER IN EDEMATOUS PATIENTS WITH CIRRHOSIS OF THE LIVER AND CONGESTIVE HEART FAILURE1 [PDF]
L. W. Birkenfeld+3 more
openalex +1 more source
ABSTRACT Although living‐donor liver transplantation (LDLT) has become the standard treatment for end‐stage liver disease, one of its major challenges is small‐for‐size syndrome (SFSS). SFSS is characterized by severe icterus and intractable ascites, although the severity of the condition can vary.
Toru Ikegami+6 more
wiley +1 more source
Abstract Background and Aims Reliable noninvasive biomarkers are an unmet clinical need for the diagnosis of NASH. This study investigates the diagnostic accuracy of the circulating triggering receptor expressed on myeloid cells 2 (plasma TREM2) as a biomarker for NASH in patients with NAFLD and elevated liver stiffness.
Vineesh Indira Chandran+17 more
wiley +1 more source
Solitary fibrous tumor of the liver (SFTL) is an exceptionally rare mesenchymal tumor, with only 117 cases reported in the literature. While most SFTs are benign, some exhibit malignant behavior, including local recurrence and metastasis.
Pengcheng Wei+18 more
doaj +1 more source
MEGALOBLASTIC ERYTHROPOIESIS IN PATIENTS WITH CIRRHOSIS OF THE LIVER [PDF]
E.R. Movitt
openalex +1 more source
Reversal of liver cirrhosis: current evidence and expectations
In the past, liver cirrhosis was considered an irreversible phenomenon. However, many experimental data have provided evidence of the reversibility of liver fibrosis. Moreover, multiple clinical studies have also shown regression of fibrosis and reversal
Y. Jung, H. Yim
semanticscholar +1 more source
Researchers develop clinlabomics assisted for cancer identification, an artificial intelligence‐powered system using routine clinical lab data to detect and identify 10 cancer types. Tested on 19 199 individuals, it achieves 90.39% sensitivity and 82.41% specificity in cancer detection, with 72.57% accuracy in identifying specific cancer types ...
Bowen Zhang+9 more
wiley +1 more source
Graphical abstract summarizing the study design, main results and key findings Abstract Background and Aims Fatty liver disease (FLD) has been associated with excess mortality. Screening for hepatic steatosis (HS) in patients with metabolic dysfunction is therefore recommended by several guidelines, despite a paucity of evidence on the clinical ...
Laurens A. van Kleef+5 more
wiley +1 more source