Results 41 to 50 of about 2,061,642 (403)
Background and aims Immunoglobulin G4-related disease (IgG4-RD) is a multisystem fibroinflammatory condition. The aim of the present study was to characterize the clinical features and therapeutic response of patients with IgG4-RD and identify risk ...
Wen An+16 more
doaj +1 more source
Interleukin-22 predicts severity and death in advanced liver cirrhosis: a prospective cohort study [PDF]
Background: Interleukin-22 (IL-22), recently identified as a crucial parameter of pathology in experimental liver damage, may determine survival in clinical end-stage liver disease.
Bachmann, Malte+11 more
core +1 more source
Chinese guidelines on the management of liver cirrhosis (abbreviated version)
Based on reviews of the literature and experts’ consensus, the Chinese Society of Hepatology developed guidelines for the diagnosis and treatment of liver cirrhosis, in order to improve clinical practice.
Xiaoyuan Xu+9 more
semanticscholar +1 more source
Regression of liver fibrosis: evidence and challenges
. It has been reported that liver fibrosis could be reversed after eliminating liver injuries. This article systematically summarizes the evidence of fibrosis regression based on histology, liver stiffness, and serum biomarkers, and discusses several ...
Ya-Meng Sun+3 more
doaj +1 more source
Immunotherapy in hepatocellular carcinoma: the complex interface between inflammation, fibrosis, and the immune response. [PDF]
Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide and confers a poor prognosis. Beyond standard systemic therapy with multikinase inhibitors, recent studies demonstrate the potential for robust and durable responses ...
Fong, Lawrence+2 more
core +2 more sources
Introduction Spider nevus and subcutaneous collateral vessel of the chest/abdominal wall are common in liver cirrhosis. This prospective study aimed to evaluate the impact of spider nevus and subcutaneous collateral vessel of the chest/abdominal wall on ...
Hongyu Li+5 more
doaj +1 more source
Pipeline for precise insoluble matrisome coverage in tissue extracellular matrices
The extracellular matrix (ECM) is assembled by hundreds of proteins orchestrating tissue patterning and surrounding cell fates via the mechanical–biochemical feedback loop.
Wei Chen+11 more
doaj +1 more source
Spontaneous porto-systemic shunts in liver cirrhosis: Clinical and therapeutical aspects
Spontaneous porto-systemic shunts (SPSS) are frequent in liver cirrhosis and their prevalence increases as liver function deteriorates, probably as a consequence of worsening portal hypertension, but without achieving an effective protection against ...
S. Nardelli+5 more
semanticscholar +1 more source
Intrahepatic cholangiocarcinoma (ICC) is highly heterogeneous. Here, the authors perform exome sequencing and bulk RNA sequencing on 73 tumor regions from 14 ICC patients to portray the multi‐faceted intratumor heterogeneity (ITH) landscape of ICC.
Xiao Xiang+14 more
doaj +1 more source