Results 41 to 50 of about 1,999,014 (306)

Idiopathic noncirrhotic portal hypertension: current perspectives [PDF]

, 2016
The term idiopathic noncirrhotic portal hypertension (INCPH) has been recently proposed to replace terms, such as hepatoportal sclerosis, idiopathic portal hypertension, incomplete septal cirrhosis, and nodular regenerative hyperplasia, used to describe ...
D'AMATI, Giulia, Gioia, Stefania, Nicoletti, Valeria, PENTASSUGLIO, ILARIA, RIGGIO, Oliviero, VALENTE, MICHELE   +5 more
core   +1 more source

IDH Mutation Subgroup Status Associates with Intratumor Heterogeneity and the Tumor Microenvironment in Intrahepatic Cholangiocarcinoma

Advanced Science, 2021
Intrahepatic cholangiocarcinoma (ICC) is highly heterogeneous. Here, the authors perform exome sequencing and bulk RNA sequencing on 73 tumor regions from 14 ICC patients to portray the multi‐faceted intratumor heterogeneity (ITH) landscape of ICC.
Xiao Xiang, Ziyang Liu, Chong Zhang, Zhao Li, Jie Gao, Changkun Zhang, Qi Cao, Jinghui Cheng, Hengkang Liu, Dingbao Chen, Qian Cheng, Ning Zhang, Ruidong Xue, Fan Bai, Jiye Zhu   +14 more
doaj   +1 more source

Interleukin-22 predicts severity and death in advanced liver cirrhosis: a prospective cohort study [PDF]

, 2012
Background: Interleukin-22 (IL-22), recently identified as a crucial parameter of pathology in experimental liver damage, may determine survival in clinical end-stage liver disease.
Bachmann, Malte, Brunner, Friederike, Filmann, Natalie, Herrmann, Eva, Kapper, Lisa, Kronenberger, Bernd, Mühl, Heiko, Pfeilschifter, Josef Martin (Prof. Dr.), Piiper, Albrecht, Rudloff, Ina, Waidmann, Oliver, Zeuzem, Stefan   +11 more
core   +1 more source

CIRRHOSIS OF THE LIVER. [PDF]

The Lancet, 1895
n ...
openaire   +3 more sources

Inhibitory effects of HNF4α on migration/maltransformation of hepatic progenitors: HNF4α-overexpressing hepatic progenitors for liver repopulation

Stem Cell Research & Therapy, 2017
Background Although they are expandable in vitro, hepatic progenitors are immature cells and share many immunomarkers with hepatocellular carcinoma, raising potential concerns regarding maltransformation after transplantation. This study investigated the
Ping Wang, Min Cong, Tianhui Liu, Hufeng Xu, Lin Wang, Guangyong Sun, Aiting Yang, Dong Zhang, Jian Huang, Yameng Sun, Wenshan Zhao, Hong Ma, Jidong Jia, Hong You   +13 more
doaj   +1 more source

Mesenchymal stem cells protect against acetaminophen hepatotoxicity by secreting regenerative cytokine hepatocyte growth factor

Stem Cell Research & Therapy, 2022
Background Acetaminophen (APAP) overdose is a major cause of the morbidity of acute liver failure. The current clinically approved treatment for APAP poisoning, N-acetylcysteine (NAC), has a limited therapeutic window, and prolonged treatment with NAC ...
Ping Wang, Yan Cui, Jing Wang, Donghua Liu, Yue Tian, Kai Liu, Xue Wang, Lin Liu, Yu He, Yufeng Pei, Li Li, Liying Sun, Zhijun Zhu, Dehua Chang, Jidong Jia, Hong You   +15 more
doaj   +1 more source

Pathogenesis of non-alcoholic fatty liver disease [PDF]

, 2009
Non-alcoholic fatty liver disease (NAFLD) represents a spectrum of disease ranging from hepatocellular steatosis through steatohepatitis to fibrosis and irreversible cirrhosis.
Abdelmalek, Adams, Adams, Aithal, Albanis, Andrews, Ayabe, Balkau, Bedogni, Belfort, Berg, Browning, Bugianesi, Cai, Chalasani, Charlton, Charlton, Chen, Chitturi, Clark, Clouston, Crespo, Davila, Day, Dixon, Donnelly, Dufour, Ekstedt, Feldstein, Franzese, Friedman, Gomez-Dominguez, Guo, Haukeland, Henderson, Hocking, Huang, Hudgins, Hui, Hyogo, Iltz, Iredale, J. K. Dowman, J.W. Tomlinson, Jou, Kammoun, Kaser, Kathirvel, Konopelska, Kugelmas, Lago, Lemoine, Lewis, Li, Lindor, Loguercio, Lord, Lutchman, Machado, Mantzoros, Marrero, Matarese, Miele, Namikawa, Nelson, Neuschwander-Tetri, Oakley, Okamoto, Olufadi, P.N. Newsome, Petta, Pikarsky, Pinzani, Postic, Preiss, P  rez-Carreras, Reynolds, Rockall, Ron, Roskams, Roskams, Sanyal, Satapathy, Saxena, Seki, Sell, Sermasathanasawadi, Solga, Svegliati-Baroni, Taniguchi, Tarantino, Tominaga, Tomita, Uygun, Valenti, van der Poorten, Van Hul, Vuppalanchi, Walker, Weltman, Whitehead, Wigg, Wilfred de Alwis, Xia, Xu, Yamaguchi, Yesilova, Yoneda, Yuan   +108 more
core   +2 more sources

Liver Cirrhosis Affects the Pharmacokinetics of the Six Substrates of the Basel Phenotyping Cocktail Differently. [PDF]

, 2022
BACKGROUND Activities of hepatic cytochrome P450 enzymes (CYPs) are relevant for hepatic clearance of drugs and known to be decreased in patients with liver cirrhosis.
Bachmann, Fabio, Bouitbir, Jamal, Duthaler, Urs, Grandinetti, Tanja, Haschke, Manuel, Hruz, Petr, Krähenbühl, Stephan, Pfefferkorn, Florian, Suenderhauf, Claudia   +8 more
core   +1 more source

Exploring novel prognostic biomarkers and biologic processes involved in NASH, cirrhosis and HCC based on survival analysis using systems biology approach [PDF]

arXiv, 2023
There is an unmet need to develop medications or drug combinations which can stop advancement of NASH to liver cirrhosis and HCC. Therefore, identifying key biomarkers based on overall survival and the exploring biological processes involved in the pathogenesis and progression of NASH toward cirrhosis and HCC to improve therapeutic interventions is ...
arxiv  

Serum Liver Fibrosis Markers for Predicting the Presence of Gastroesophageal Varices in Liver Cirrhosis: A Retrospective Cross-Sectional Study

Gastroenterology Research and Practice, 2015
Background and Aims. A retrospective cross-sectional study was conducted to evaluate the role of hyaluronic acid (HA), laminin (LN), amino-terminal propeptide of type III procollagen (PIIINP), and collagen IV (CIV) in predicting the presence of ...
Xingshun Qi, Hongyu Li, Jiang Chen, Chunlian Xia, Ying Peng, Junna Dai, Yue Hou, Han Deng, Jing Li, Xiaozhong Guo   +9 more
doaj   +1 more source