Results 41 to 50 of about 410,300 (316)
Amiloride reduces portal hypertension in rat liver cirrhosis [PDF]
, 2010 Objective This study aimed to investigate the effect of amiloride on portal hypertension. Amiloride is known to inhibit Na(+)/H(+) exchangers on activated hepatic stellate cells.
Beitinger, Frigga +6 more
core +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
An Analysis of Immunoreactive Signatures in Early Stage Hepatocellular Carcinoma
EBioMedicine, 2015 Background: Hepatocellular carcinoma (HCC) is prevalent worldwide and early diagnosis of HCC is critical for effective treatment and optimal prognosis.
Yu Hong +26 more
doaj +1 more source
NKG2D Enhances Double-Negative T Cell Regulation of B Cells
Frontiers in Immunology, 2021 Numerous studies reported a small subpopulation of TCRαβ+CD4-CD8- (double-negative) T cells that exert regulatory functions in the peripheral lymphocyte population. However, the origin of these double-negative T (DNT) cells is controversial.
Shi-hua Hu +11 more
doaj +1 more source
The Royal Free Hospital score: a calibrated prognostic model for patients with cirrhosis admitted to intensive care unit. Comparison with current models and CLIF-SOFA score [PDF]
, 2014 Prognosis for patients with cirrhosis admitted to intensive care unit (ICU) is poor. ICU prognostic models are more accurate than liver-specific models.
Agarwal, B +6 more
core +1 more source
Molecular Oncology, EarlyView.This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima +6 more
wiley +1 more source
International Journal of Infectious Diseases, 2018 Background: The numbers of articles reporting randomized controlled trials (RCTs) on viral hepatitis in China have been increasing, but there have been few systematic studies evaluating the reporting quality of RCTs in this field.
Na Zeng +7 more
doaj +1 more source
Survival COVID-19 in Adult Patients with Liver Cirrhosis
The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2021 Background: COVID-19 is a disease caused by infection of SARS-CoV-2 virus which leads to mortality due to respiratory failure. The progression of COVID-19 is more severe in patients with pre-existence morbidities, including liver disease. Recently, a few
Gita Aprilicia +9 more
doaj +1 more source
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
Hemostatic Abnormalities in Patient with Liver Cirrhosis: A Review
Jurnal Kedokteran Diponegoro, 2022 Liver cirrhosis is one of Indonesia’s most common liver diseases, where the incidence is 38 – 52.8% of all liver diseases. Liver cirrhosis refers to a late-stage pathological lesion caused by the accumulation of extracellular matrix in the liver ...
Wahyuni Wahyuni, Diana Novita
doaj +1 more source