Results 41 to 50 of about 385,913 (358)

Immunotherapy in hepatocellular carcinoma: the complex interface between inflammation, fibrosis, and the immune response. [PDF]

, 2019
Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide and confers a poor prognosis. Beyond standard systemic therapy with multikinase inhibitors, recent studies demonstrate the potential for robust and durable responses ...
Fong, Lawrence, Keenan, Bridget P, Kelley, Robin K   +2 more
core   +2 more sources

Autologous Bone Marrow Infusion Activates the Progenitor Cell Compartment in Patients with Advanced Liver Cirrhosis

Cell Transplantation, 2010
Several clinical trials of bone marrow cell infusion in patients with liver cirrhosis (LC) have shown clinical improvement, despite conflicting results from animal models.
Ja Kyung Kim, Young Nyun Park, Jin Seok Kim, Mi-Suk Park, Yong Han Paik, Jae-Yeon Seok, Yong Eun Chung, Hyun Ok Kim, Kyung Sik Kim, Sang Hoon Ahn, Do Young Kim, Myeong-Jin Kim, Kwan Sik Lee, Chae Yoon Chon, Soo Jeong Kim, Shuji Terai, Isao Sakaida, Kwang-Hyub Han   +17 more
doaj   +1 more source

Assessment and validation of the TREAT-B score to assess the treatment eligibility of patients with chronic hepatitis B virus infection

Frontiers in Medicine, 2022
Background and aimsAccess to Hepatitis B virus (HBV) DNA testing to determine treatment eligibility is limited in low-income countries. Therefore, this study aimed to assess and validate the TREAT-B score proposed as the treatment threshold in an Asian ...
Kessarin Thanapirom, Kessarin Thanapirom, Kessarin Thanapirom, Sirinporn Suksawatamnuay, Sirinporn Suksawatamnuay, Sirinporn Suksawatamnuay, Panarat Thaimai, Panarat Thaimai, Panarat Thaimai, Sombat Treeprasertsuk, Piyawat Komolmit, Piyawat Komolmit, Piyawat Komolmit, Pisit Tangkijvanich   +13 more
doaj   +1 more source

Telomere shortening as genetic risk factor of liver cirrhosis [PDF]

, 2015
Cirrhosis is the main complication of chronic liver disease, leads to progressive liver function impairment and is the main risk factor for the development of liver cancer.
Carulli, Lucia
core   +1 more source

Serum Mac-2-binding protein glycosylation isomer predicts esophagogastric varices in cirrhotic patients with chronic hepatitis C virus infection treated with IFN-free direct-acting antiviral agent: M2BPGi levels predict varices in SVR patients

Annals of Hepatology, 2020
Introduction and objectives: We examined whether Mac-2-binding protein glycosylation isomer (M2BPGi) levels could be a predictive marker for the presence of esophagogastric varices (EGV) in cirrhotic patients after hepatitis C virus (HCV) eradication ...
Kanako Kikukawa, Sawako Uchida-Kobayashi, Akihiro Tamori, Kanako Yoshida, Kohei Kotani, Hiroyuki Motoyama, Ritsuzo Kozuka, Atsushi Hagihara, Hideki Fujii, Hiroyasu Morikawa, Masaru Enomoto, Yoshiki Murakami, Norifumi Kawada   +12 more
doaj  

Endothelin-3 like immunoreactivity in plasma of patients with cirrhosis of the liver [PDF]

, 1992
A highly specific and sensitive radioimmunoassay (RIA) has been established for determination of endothelin-3 like immunoreactivity in human plasma to investigate its possible role in hemodynamic alterations due to liver disease.
Alexander L. Gerbes, Angelika M. Vollmar, De Gouville, Fukuda, Gerbes, Gerbes, Gerbes, Gustav Paumgartner, Inoue, Masaki, Matsumoto, Miyauchi, Miyauchi, Nayler, Randall, Samson, Suzuki, Veit Gülberg, Yanagisawa   +18 more
core   +1 more source

Improvement of glucose and lipid metabolism with pegylated interferon-α plus ribavirin therapy in Chinese patients chronically infected with genotype 1b hepatitis C virus

Annals of Saudi Medicine, 2015
BACKGROUND: Many epidemiological studies have demonstrated a significant association between Type 2 diabetes mellitus and abnormal lipid profiles with chronic HCV genotype 1 (GT1) infection.
Shao Qing, Dong Ji, Bing Li, Fan Li, Yudong Wang, Xioaxia Niu, Binfang Ling, Yuhua Meng, George Lau, Guofeng Chen   +9 more
doaj   +1 more source

Indications for liver transplantation in the cyclosporine era [PDF]

, 1985
One hundred seventy orthotopic liver transplants were performed under conventional immunosuppression with azathioprine and steroids with 1- and 5-year survivals of 32.9% and 20.0%, respectively.
Borel, Byers W. Shaw, Calne, Carlos O. Esquivel, Hanto, Hume, Iwatsuki, James, Kapelman, LaRusso, Lefkowitch, Lewis, Matloff, Neuberger, Opelz, Peters, Robert D. Gordon, Roll, Rosenthal, Shaw, Shaw, Shaw, Shaw, Shunzaburo Iwatsuki, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Summerfield, Thomas, Thomas E. Starzl, Tzakis, Weiss   +36 more
core   +1 more source

An Analysis of Immunoreactive Signatures in Early Stage Hepatocellular Carcinoma

EBioMedicine, 2015
Background: Hepatocellular carcinoma (HCC) is prevalent worldwide and early diagnosis of HCC is critical for effective treatment and optimal prognosis.
Yu Hong, Jiang Long, Hai Li, Shuhong Chen, Qiqi Liu, Bei Zhang, Xiaomin He, Yan Wang, Hongyi Li, Yimei Li, Tao Zhang, Chenzhen Lu, Hao Yan, Minli Zhang, Qing Li, Bangwei Cao, Zhigang Bai, Jin Wang, Zhongtao Zhang, Shengtao Zhu, Jiasheng Zheng, Xiaojuan Ou, Hong Ma, Jidong Jia, Hong You, Shengqi Wang, Jian Huang   +26 more
doaj   +1 more source

NKG2D Enhances Double-Negative T Cell Regulation of B Cells

Frontiers in Immunology, 2021
Numerous studies reported a small subpopulation of TCRαβ+CD4-CD8- (double-negative) T cells that exert regulatory functions in the peripheral lymphocyte population. However, the origin of these double-negative T (DNT) cells is controversial.
Shi-hua Hu, Long-hui Zhang, Jie Gao, Jing-heng Guo, Xiao-dong Xun, Xiao Xiang, Qian Cheng, Qian Cheng, Zhao Li, Zhao Li, Ji-ye Zhu, Ji-ye Zhu   +11 more
doaj   +1 more source