Results 11 to 20 of about 11,463,276 (314)

A multi-society Delphi consensus statement on new fatty liver disease nomenclature.

Journal of Hepatology, 2023
The principal limitations of the terms NAFLD and NASH are the reliance on exclusionary confounder terms and the use of potentially stigmatising language.
M. Rinella, J. Lazarus, V. Ratziu, S. Francque, A. Sanyal, F. Kanwal, D. Romero, M. Abdelmalek, Q. Anstee, J. Arab, M. Arrese, R. Bataller, U. Beuers, J. Boursier, E. Bugianesi, C. Byrne, G. C. Castro Narro, A. Chowdhury, H. Cortez‐Pinto, D. Cryer, K. Cusi, Mohamed El‐Kassas, S. Klein, Wayne Eskridge, Jian-Gao Fan, S. Gawrieh, C. Guy, S. Harrison, Seung-Up Kim, B. Koot, Marko Korenjak, K. Kowdley, F. Lacaille, R. Loomba, R. Mitchell-Thain, T. Morgan, Elisabeth Powell, M. Roden, M. Romero‐Gomez, Marcelo Silva, S. Singh, S. Sookoian, C. W. Spearman, D. Tiniakos, Luca Valenti, M. Vos, Vincent Wai‐Sun Wong, S. Xanthakos, Y. Yılmaz, Z. Younossi, Ansley Hobbs, Marcela Villota-Rivas, P. Newsome   +52 more
semanticscholar   +2 more sources

Serum Glial Cell Line-Derived Neurotrophic Factor (sGDNF) Is a Novel Biomarker in Predicting Cirrhosis in Patients with Chronic Hepatitis B

Canadian Journal of Gastroenterology and Hepatology, 2022
Objectives. We assessed the potential of glial cell line-derived neurotrophic factor (GDNF) as a useful biomarker to predict cirrhosis in chronic hepatitis B (CHB) patients. Methods.
Guangyue Yang, Liping Zhuang, Tiantian Sun, Yee Hui Yeo, Le Tao, Wei Zhang, Wenting Ma, Liu Wu, Zongguo Yang, Yanqin Yang, Dongying Xue, Jie Zhang, Rilu Feng, Ebert Matthias P., Steven Dooley, Ekihiro Seki, Ping Liu, Cheng Liu   +17 more
doaj   +1 more source

Extracellular Vesicle-Encapsulated MicroRNA-375 from Bone Marrow-Derived Mesenchymal Stem Cells Inhibits Hepatocellular Carcinoma Progression through Regulating HOXB3-Mediated Wnt/β-Catenin Pathway

Analytical Cellular Pathology, 2022
Nowadays, microRNA-375 (miR-375) has been implicated in many types of cancers, including hepatocellular carcinoma (HCC), and the functions of miRNAs encapsulated by extracellular vesicles (EV) in HCC progression have also been extensively investigated ...
Zhaoxia Yu, Ju Liu, Qiqi Fan, Jun Yu, Xiaoting Ren, Xiaobin Wang   +5 more
doaj   +1 more source

Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A State-of-the-Art Review

Journal of Obesity & Metabolic Syndrome, 2023
Metabolic dysfunction-associated steatotic liver disease (MASLD) is the latest term for steatotic liver disease associated with metabolic syndrome.
W. Chan, Kee-Huat Chuah, R. Rajaram, Lee-Ling Lim, J. Ratnasingam, S. Vethakkan   +5 more
semanticscholar   +1 more source

Effect of Transcatheter Arterial Chemoembolization Combined with Radiofrequency Ablation on Liver Function and Immune Function in Patients with Hepatocellular Carcinoma

Emergency Medicine International, 2022
Objectives. To investigate the effects of transcatheter arterial chemoembolization (TACE) combined with radiofrequency ablation (RFA) on liver function and immune function in patients with hepatocellular carcinoma (HCC). Methods.
Yan Zhou, Ying Qian, Weiming Xiong, Naijun Yan, Bing Hu, Zhiyuan Xiong, Weixin He   +6 more
doaj   +1 more source

Identification of immune-related target and prognostic biomarkers in PBMC of hepatocellular carcinoma

BMC Gastroenterology, 2023
Background  Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide, and is characterized by insidious onset, rapid progression, and poor prognosis. Immunotherapy is a first-line treatment for advanced HCC.
Rui Hu, Wei Zhang, Zhiyi Han, Mengqing Ma, Qi Huang, Minling Lv, Wenfeng Ma, Xinfeng Sun, Wenxing Feng, Jing Li, Xin Zhong, Jialing Sun, Wei Yao, Xiaozhou Zhou   +13 more
doaj   +1 more source

FAT4 expression in peripheral blood mononuclear cells is associated with prognosis and immune cell infiltration in hepatocellular carcinoma

Scientific Reports, 2023
Peripheral blood mononuclear cell (PBMC) genes reflect the host immune status and could be suitable for evaluating the prognosis of patients with hepatocellular carcinoma (HCC), for which a reliable biomarker is unavailable and the host immune responses ...
Jing Li, Minling Lv, Qi Huang, Rui Hu, Xin Zhong, Xinfeng Sun, Wenxing Feng, Zhiyi Han, MengQing Ma, Wei Zhang, Xiaozhou Zhou   +10 more
doaj   +1 more source

MAFLD: A consensus-driven proposed nomenclature for metabolic associated fatty liver disease.

Gastroenterology, 2020
Fatty liver associated with metabolic dysfunction is common, affects a quarter of the population, and has no approved drug therapy. While pharmacotherapies are in development, response rates appear modest.
M. Eslam, A. Sanyal, J. George
semanticscholar   +1 more source

Non-alcoholic fatty liver disease (NAFLD): a review of pathophysiology, clinical management and effects of weight loss

BMC Endocrine Disorders, 2022
Given the increasing prevalence of diabetes and obesity worldwide, the deleterious effects of non-alcoholic fatty liver disease (NAFLD) are becoming a growing challenge for public health.
S. Pouwels, N. Sakran, Yitka Graham, A. Leal, T. Pintar, Wah Yang, R. Kassir, R. Singhal, K. Mahawar, D. Ramnarain   +9 more
semanticscholar   +1 more source

Prognostic potential and mechanism of SORT1 and its co‐expressed genes in hepatocellular carcinoma based on integrative analysis of multiple database

Precision Medical Sciences, 2022
Abnormal SORT1 expression has been reported in various cancers. However, the expression and function of SORT1 in hepatocellular carcinoma (HCC) remain to be explored.
Minjie Lin, Mengying Zhu, Tingqiu Ge, Naiying Lu, Xiling Fu, Jiabao Chang   +5 more
doaj   +1 more source