Results 91 to 100 of about 1,672,248 (364)

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Toward finding the difference between untreated celiac disease and COVID-19 infected patients in terms of CD4, CD25 (IL-2 Rα), FOXP3 and IL-6 expressions as genes affecting immune homeostasis

BMC Gastroenterology, 2021
Background Coronavirus disease 2019 (COVID-19) is defined as an emerging infectious disease caused by severe acute respiratory syndrome coronavirus 2 and celiac disease (CD) is one of the autoimmune multiorgan diseases, which can be accompanied by an ...
Nastaran Asri, Ehsan Nazemalhosseini Mojarad, Hamed Mirjalali, Seyed Reza Mohebbi, Kaveh Baghaei, Mohammad Rostami-Nejad, Abbas Yadegar, Mostafa Rezaei-Tavirani, Hamid Asadzadeh Aghdaei, Kamran Rostami, Andrea Masotti   +10 more
doaj   +1 more source

Immunoglobulin A and liver diseases [PDF]

Journal of Gastroenterology, 2017
Immunoglobulin A (IgA) is a major immunoglobulin isotype in the gut and plays a role in maintenance of gut homeostasis. Secretory IgA (SIgA) has multiple functions in the gut, such as to regulate microbiota composition, to protect intestinal epithelium from pathogenic microorganisms, and to help for immune-system development.
Tatsuo Inamine, Bernd Schnabl
openaire   +3 more sources

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Incidence of hepatocellular carcinoma in hepatitis C cirrhotic patients with and without HIV infection: a cohort study, 1999-2011

Annals of Hepatology, 2014
Introduction. High activity antiretroviral therapy (HAART) has allowed people infected with human immunodeficiency virus (HIV) to live longer. In the course of time, hepatocellular carcinoma (HCC) began to be found in these patients.
Nicolas Di Benedetto, Mirta Peralta, Estela Alvarez, María Teresa Schroder, Claudio Estepo, Silvia Paz, Hugo Fainboim   +6 more
doaj  

Isoniazid and Rifampicin Produce Hepatic Fibrosis through an Oxidative Stress-Dependent Mechanism

International Journal of Hepatology, 2020
Background & Aims. Chronic hepatitis (CH) has emerged as a distinct outcome of drug-induced liver injury (DILI). Combination therapy of Isoniazid (INH) and Rifampicin (RMP) which is widely used for prolonged periods can cause acute hepatotoxicity and has
Ayan Biswas, Suman Santra, Debasree Bishnu, Gopal Krishna Dhali, Abhijit Chowdhury, Amal Santra   +5 more
doaj   +1 more source

Tropical liver disease [PDF]

Medicine, 2007
The liver is frequently involved in infections that are prevalent in different regions of the tropics, and chronic liver disease, sometimes with multiple aetiological explanations, is an important cause of early morbidity and mortality. This article describes some hepatic and biliary problems that are seen in the tropics, or which may be imported from ...
Nicholas J. Beeching, Nicholas J. Beeching, Anuradha S Dassanayake, Anuradha S Dassanayake   +3 more
openaire   +1 more source

Pediatric liver transplantation [PDF]

, 1987
Liver transplantation, which once was an experimental procedure of no practical interest, has become the preferred treatment for infants and children dying of almost all non-neoplastic end-stage liver diseases. Liver replacement is being provided by many
Esquivel, C, Gordon, R, Starzl, TE, Todo, S   +3 more
core  

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Relationship between ureB Sequence Diversity, Urease Activity and Genotypic Variations of Different Helicobacter pylori Strains in Patients with Gastric Disorders [PDF]

Polish Journal of Microbiology, 2016
Association of the severity of Helicobacter pylori induced diseases with virulence entity of the colonized strains was proven in some studies. Urease has been demonstrated as a potent virulence factor for H. pylori.
Hossein Ghalehnoei, Alireza Ahmadzadeh, Nastaran Farzi, Masoud Alebouyeh, Hamid Asadzadeh Aghdaei, Pedram Azimzadeh, Mahsa Molaei, Mohammad Reza Zali   +7 more
doaj   +1 more source