Results 111 to 120 of about 1,826,226 (307)

Nuclear shuttling of key methionine cycle enzymes in acute liver injury [PDF]

, 2017
Artículo para la web de Divulgación Atlas of Science.Important metabolic enzymes have been classically ascribed to certain subcellular locations, where they perform their well-known function.
Pajares, María Ángeles
core  

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Evaluation of coagulation parameters and liver enzymes among alcohol drinkers in Port Harcourt, Nigeria

, 2013
Teddy Charles Adias,1 Everton Egerton,2 Osaro Erhabor3 1Bayelsa College of Health Technology, Bayelsa State, Nigeria; 2Department of Medical Laboratory Science, Rivers State University of Science and Technology, Port Harcourt, Nigeria; 3Faculty of ...
Erhabor O, Adias TC, Egerton E
core  

Daily rhythms in metabolic liver enzymes and plasma glucose require a balance in the autonomic output of the liver.

, 2008
Daily variations in plasma glucose concentrations are controlled by the biological clock, located in the suprachiasmatic nucleus. Our previous studies indicated an important role for the sympathetic innervation of the liver in the generation of the daily
Habold, C., Kalsbeek, A., van Heijningen, Caroline, van der Vliet, Jan, van der Plasse, G., Pévet, Paul, Pevet, P., van der Plasse, Geoffrey, Buijs, R.M., Kalsbeek, Andries, Cailotto, Cathy, Buijs, Ruud M., Heijningen, C.L., van der Vliet, J., Habold, Caroline, Cailotto, C.   +15 more
core   +1 more source

Fetal liver blood flow distribution: role in human developmental strategy to prioritize fat deposition versus brain development [PDF]

, 2012
Among primates, human neonates have the largest brains but also the highest proportion of body fat. If placental nutrient supply is limited, the fetus faces a dilemma: should resources be allocated to brain growth, or to fat deposition for use as a ...
Crozier, SR, Sarah R. Crozier, Sian M. Robinson, Guttorm Haugen (141243), Sarah R Crozier, Kiserud, T., Hanson, M.A., Inskip, H.M., Haugen Guttorm, Nicholas C. W. Harvey, Harvey Nicholas C. W., Crozier Sarah R., Haugen, G., Hazel M. Inskip, Robinson Sian M., Crozier, S.R., Inskip, HM, Mark A. Hanson (114427), Cyrus Cooper (141250), Godfrey, Keith M., Sian M Robinson, Mark A Hanson, Cyrus Cooper, Cooper Cyrus, Lucy Davies, Harvey, NC, Hazel M. Inskip (141248), Haugen, G, Guttorm Haugen, Harvey, N.C., Godfrey Keith M., Kiserud, T, Robinson, S.M., Mark A. Hanson, Keith M Godfrey, Nicholas C W Harvey, Hanson Mark A., Torvid Kiserud, Southampton Women's Survey Study Group, Cooper, Cyrus, Davies, L, Hanson, MA, Sarah R. Crozier (141254), Keith M. Godfrey, Inskip Hazel M., Godfrey, KM, Hazel M Inskip, Sian M. Robinson (141258), Kiserud Torvid, Keith M. Godfrey (141238), Cooper, C., Robinson, SM, Davies Lucy, Cooper, C, Torvid Kiserud (141246), Lucy Davies (141261), Davies, L., Nicholas C. W. Harvey (141252)   +57 more
core   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

The endogenous production of hydrogen sulphide in intrauterine tissues [PDF]

, 2009
Background: Hydrogen sulphide is a gas signalling molecule which is produced endogenously from L-cysteine via the enzymes cystathionine beta-synthase (CBS) and cystathionine gamma-lyase (CSE).
Patel Pushpa, Carson Ray J, Patel, Pushpa, Heptinstall, John, Heptinstall, J, Wang, Rui, Carson, RJ, Rui Wang, John Heptinstall (7594472), Pushpa Patel, Carson, Ray J., Pushpa Patel (2697712), Heptinstall John, Rui Wang (52434), Vatish Manu, Vatish, M, Ray J Carson, Manu Vatish (187260), Wang Rui, Wang, R, Ray J. Carson (7594475), Vatish, Manu, Manu Vatish, John Heptinstall   +23 more
core   +1 more source

Allopurinol-Induced Granulomatous Hepatitis: A Case Report and Review of Literature

Journal of Investigative Medicine High Impact Case Reports, 2017
Liver enzyme elevation is a common reason for referral to a gastroenterologist. Drugs are one of the most common reasons for asymptomatic elevation of liver enzymes.
Umair Iqbal MD, Hafiz Umair Siddiqui MBBS, Hafsa Anwar MBBS, Ahmad Chaudhary MD, Abdulhadi Affan Quadri MD   +4 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Exploring the Association between Elevated Liver Enzymes and Diabetes in the PERSIAN Guilan Cohort Study [PDF]

Caspian Journal of Internal Medicine
Background: Diabetes mellitus (DM) is highly consequential to global health among chronic diseases. Due to a limited researches that have examined relationships between liver enzymes and DM, this study aimed to investigate the link between elevated liver
Mohammad Taghi Ashoobi, Farahnaz Joukar, Kourosh Mojtahedi, Saman Maroufizadeh, Mohammadreza Javid, Ali Parvaneh, Tahereh Zeinali, Niloofar Faraji, Mohammadreza Naghipour, Fariborz Mansour-Ghanaei   +9 more
doaj