Results 141 to 150 of about 1,119,883 (334)

Peripheral infusion of human umbilical cord mesenchymal stem cells rescues acute liver failure lethality in monkeys

Stem Cell Research & Therapy, 2019
Background Acute liver failure (ALF) is a complicated clinical syndrome associated with high mortality, with liver transplantation as the only treatment option.
Gang Guo, Xiang Zhuang, Qing Xu, Zhenru Wu, Yongjie Zhu, Yongjie Zhou, Yuanmin Li, Yanrong Lu, Bo Zhang, Prue Talbot, Jiayu Liao, Junjun She, Hong Bu, Yujun Shi   +13 more
doaj   +1 more source

Evaluation of encapsulated liver cell spheroids in a fluidised-bed bioartificial liver for treatment of ischaemic acute liver failure in pigs in a translational setting [PDF]

, 2013
Liver failure is an increasing problem. Donor-organ shortage results in patients dying before receiving a transplant. Since the liver can regenerate, alternative therapies providing temporary liver-support are sought.
Selden, Clare, Spearman, Catherine Wendy, Kahn, Delawir, Miller, Malcolm, Figaji, Anthony, Erro, Eloy, Bundy, James, Massie, Isobel, Chalmers, Sherri-Ann, Arendse, Hiram   +9 more
core   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

Acute liver failure as initial presentation in a Chinese patient with Budd-Chiari syndrome due to protein C deficiency: A case report and literature review

Heliyon
Acute liver failure is an uncommon presentation in the clinic. Common causes for acute liver failure include viral hepatitis and drug-related hepatotoxicity. However, acute liver failure due to Budd-Chiari syndrome is rare.
Wanling Xu, Wenjing Tang, Weiying Yang, Lichao Sun, Wei Li, Shouqing Wang, Xiuxian Zang   +6 more
doaj   +1 more source

Liver Failure: Acute and Acute on Chronic

Definitions, 2020

semanticscholar   +1 more source

Prognostic Implications of Sleep Architecture for Patients Admitted to the Intensive Care Unit With Status Epilepticus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu, Marcus C. Ng, Gavin P. Winston, Sabrina Schaly, Garima Shukla, Lysa Boissé Lomax   +5 more
wiley   +1 more source

Up-regulation of the anti-inflammatory adipokine adiponectin in acute liver failure in mice [PDF]

, 2006
BACKGROUND/AIMS: Recent reports suggest that the adipose tissue and adipokines are potent modulators of inflammation. However, there is only scarce knowledge on the functional role and regulation of endogenous adiponectin in non-fat tissues such as the ...
Avila, M.A. (Matías Antonio), Berasain, C. (Carmen), Enrich, B. (Barbara), Moschen, A.R. (Alexander R.), Rumpold, H. (Holger), Tilg, H. (Herbert), Wolf, A.M. (Anna María), Wolf, D. (Dominik)   +7 more
core  

Direct molecular and spectroscopic evidence for increased ammonia removal capacity of skeletal muscle in acute liver failure

, 2006
BACKGROUND/AIMS: It has been proposed that, in acute liver failure, skeletal muscle adapts to become the principle organ responsible for removal of blood-borne ammonia by increasing glutamine synthesis, a reaction that is catalyzed by the cytosolic ATP ...
Butterworth, Roger, Chatauret, Nicolas, Desjardins, Paul, Rao, Rama K. V., Rose, Christopher, Zwingmann, Claudia   +5 more
core   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source