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Acute Liver Failure

AACN Advanced Critical Care, 2016
Acute liver failure, also known as fulminant hepatic failure, is a rare life-threatening disease that has a high mortality rate and affects many organ systems. Causes of acute liver failure vary—it can be attributed to drugs, viruses, and other uncommon sources.
Ami, Grek, Lisa, Arasi
openaire   +4 more sources

Acute liver failure

Best Practice & Research Clinical Gastroenterology, 2013
Untreated acute liver failure (ALF) has a poor outcome and so rapid diagnosis and management is vital if the patient is to survive. ALF has such profound and widespread physiological consequences that whenever possible, patients with ALF should be managed in an intensive care unit. Management is to support the physiology and treat the underlying cause.
Tony Whitehouse, Julia Wendon
openaire   +3 more sources

Plasma Exchange in Acute and Acute on Chronic Liver Failure

Seminars in liver disease (Print), 2021
Liver failure in the context of acute (ALF) and acute on chronic liver failure (ACLF) is associated with high mortality in the absence of a liver transplant.
R. Maiwall, S. Sarin
semanticscholar   +1 more source

Acute liver failure

The Lancet
Acute liver failure (ALF) is a life-threatening disorder characterised by rapid deterioration of liver function, coagulopathy, and hepatic encephalopathy in the absence of pre-existing liver disease. The cause of ALF varies across the world. Common causes of ALF in adults include drug toxicity, hepatotropic and non-hepatotropic viruses, herbal and ...
Maiwall R.   +3 more
openaire   +6 more sources

Acute liver failure

Current Opinion in Gastroenterology, 2001
Worldwide, viral hepatitis is the leading cause of acute liver failure, whereas acetaminophen hepatotoxicity is the most commonly identified cause in Western countries. Restricting the quantity of acetaminophen tablets dispensed has been shown to reduce morbidity and mortality in countries with a high incidence of acetaminophen overdose.
R J, Fontana, L G, Quallich
openaire   +4 more sources

Acute liver failure

The Indian Journal of Pediatrics, 2003
Acute liver failure in children is associated with a high mortality. Most cases in our setup are due to water borne hepatotropic viruses HAV and HEV. The clinician must be aware of the earliest and the subtle signs of acute liver failure to identify cases early enough and institute supportive therapy.
N K, Arora   +3 more
openaire   +2 more sources

Liver transplantation for acute liver failure and acute-on-chronic liver failure

American Journal of Transplantation
Acute liver failure (ALF) and acute-on-chronic liver (ACLF) are distinct phenotypes of liver failure and, thus, need to be compared and contrasted for appropriate management. There has been a significant improvement in the outcomes of these patients undergoing liver transplantation (LT).
Anand V. Kulkarni   +2 more
openaire   +2 more sources

Systematic review with meta‐analysis: liver transplant provides survival benefit in patients with acute on chronic liver failure

Alimentary Pharmacology and Therapeutics, 2020
Data on liver transplantation (LT) in acute on chronic liver failure (ACLF) are scanty.
Mohamed A. Abdallah   +6 more
semanticscholar   +1 more source

Acute liver failure

Current Opinion in Critical Care, 2011
Acute liver failure (ALF) results in a multitude of serious complications that often lead to multi-organ failure. This brief review focuses on the pathophysiological processes in ALF and how to manage these.The clinical presentation in ALF ranges from slightly altered conscious level with profound coagulopathy to coma with a catastrophic failure of ...
Fin Stolze, Larsen   +1 more
openaire   +4 more sources

Acute Liver Failure

Clinics in Liver Disease, 2017
Acute liver failure (ALF) is a life-threatening condition of heterogeneous etiology. Outcomes are better with early recognition and prompt initiation of etiology-specific therapy, intensive care protocols, and liver transplantation (LT). Prognostic scoring systems include the King's College Criteria and Model for End-stage Liver Disease score. Cerebral
Chalermrat, Bunchorntavakul   +1 more
openaire   +2 more sources

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