Results 41 to 50 of about 585,288 (267)

Two sides of one coin: massive hepatic necrosis and progenitor cell-mediated regeneration in acute liver failure

open access: yesFrontiers in Physiology, 2015
Massive hepatic necrosis is a key event underlying acute liver failure, a serious clinical syndrome with high mortality. Massive hepatic necrosis in acute liver failure has unique pathophysiological characteristics including extremely rapid parenchymal ...
Honglei eWeng   +6 more
doaj   +1 more source

Biallelic mutations in NBAS cause recurrent acute liver failure with onset in infancy [PDF]

open access: yes, 2015
Acute liver failure (ALF) in infancy and childhood is a life-threatening emergency. Few conditions are known to cause recurrent acute liver failure (RALF), and in about 50% of cases, the underlying molecular cause remains unresolved.
Bader, Daniel M.   +31 more
core   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

open access: yesFEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali   +3 more
wiley   +1 more source

Liver Transplantation for Acute Liver Failure due to Mushroom Poisoning

open access: yesThe Turkish Journal of Gastroenterology
Background/Aims: Liver transplantation is a life-saving approach in some cases of mushroom poisoning, which is one of the important causes of acute liver failure. However, debate continues regarding the timing of liver transplantation.
Hayri Canbaz   +4 more
doaj   +1 more source

Acute liver failure in adults [PDF]

open access: yesКлиническая микробиология и антимикробная химиотерапия, 2019
This article summarizes data on etiology, epidemiology and clinical presentation of acute liver failure. The review provides statistics on the incidence rates of acute liver failure in patients with different underlying diseases, describes the most ...
Lukashik S.P., Karpov I.A.
doaj   +1 more source

Prognostic Markers in Pediatric Acute Liver Failure

open access: yesGE: Portuguese Journal of Gastroenterology, 2023
Introduction: Acute liver failure (ALF), although rare in children, is a complex progressive pathology, with multisystem involvement and high mortality.
Andreia Filipa Nogueira   +6 more
doaj   +1 more source

Coexisting Sickle Cell Anemia and Sarcoidosis: A Management Conundrum! [PDF]

open access: yes, 2017
Sickle cell disease and Sarcoidosis are conditions that are more common in the African American population. In this report we share an unfortunate patient who had hepatic sarcoidosis but could not receive steroids since that precipitated acute liver ...
Gollahalli, Nagesh S., Nutan, FNU
core   +3 more sources

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Issues of intensive care and liver transplantation tactics in fulminant liver failure

open access: yesВестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2023
Fulminant liver failure is usually characterized as severe acute liver injury with encephalopathy and synthetic dysfunction (international normalized ratio [INR] ≥1.5) in a patient without cirrhosis or previous liver disease.
L. U. Agumava   +10 more
doaj   +1 more source

Acute Liver Failure: An Up-To-Date Approach [PDF]

open access: yes, 2017
Acute liver failure is a rare but potentially devastating disease. Throughout the last few decades, acute liver failure outcomes have been improving in the context of the optimized overall management.
Bagulho, L   +3 more
core   +1 more source

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