Results 191 to 200 of about 509,312 (356)

Redox‐Responsive Tellurium‐Bridged Covalent Organic Frameworks/PEG Composites for Targeted Therapy of Diabetic Cardiomyopathy

Advanced Science, EarlyView.
This study unlocks the immense potential of COF@polymer nanocomposites as a multifunctional therapeutic platform for targeted drug delivery in diabetic cardiomyopathy. Abstract Diabetic cardiomyopathy, a major complication of diabetes, is strongly associated with elevated levels of glycated hemoglobin (HbA1c) and reactive oxygen species (ROS). However,
Jing Xue, Jialu Zhuang, Taotao Fan, Songtao Tang, Junjun Wang, Xiaohui Liu, Jian Liu, Jin Shi, Jiaji Li, Wanjun Li, Danyou Hu, Xiaoqian Zhang, Hua Wang, Guiyang Zhang   +13 more
wiley   +1 more source

Novel regulators of hepatic macrophages in liver fibrosis. [PDF]

Front Immunol
Tang X, Bai M, Du X, Wang H, Liu M, Fu X, Zhang H, Liang S, Wang L.   +8 more
europepmc   +1 more source

Curcumin Attenuates Angiogenesis in Liver Fibrosis and Inhibits Angiogenic Properties of Hepatic Stellate Cells

, 2013
Feng Zhang, Li Chen, Desong Kong, Xiao–Ping Zhang, Xiaojing Zhu, Lu Yin, Shizhong Zheng   +6 more
openalex   +1 more source

Wearable and Implantable Devices for Continuous Monitoring of Muscle Physiological Activity: A Review

Advanced Science, EarlyView.
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao, Ata Golparvar, Mohammad Javad Bathaei, Filipe Arroyo Cardoso, Clementine M. Boutry   +4 more
wiley   +1 more source

Thyroid function and liver fibrosis: FT3 levels are inversely and independently correlated with enhanced liver fibrosis score in solid organ transplant patients with dysglycemia. [PDF]

Front Immunol
Leanza C, Giusti MA, Miceli V, Zito G, Tinnirello R, Iannolo G, Galante A, Emanuele F, Amato M, Lo Iacono G, Lo Re V, Gruttadauria S, Calogero AE, Pinzani M, Mattina A.   +14 more
europepmc   +1 more source

Synbiotics Alter Fecal Microbiomes, But Not Liver Fat or Fibrosis, in a Randomized Trial of Patients With Nonalcoholic Fatty Liver Disease

, 2020
Eleonora Scorletti, Paul R. Afolabi, Elizabeth A. Miles, Debbie E. Smith, Amal Almehmadi, Albandri Saleh Alshathry, Caroline E. Childs, Stefania Del Fabbro, Josh Bilson, Helen Moyses, Geraldine Clough, Jaswinder K. Sethi, Janisha Patel, Mark Wright, David J. Breen, Charles Peebles, Angela Darekar, Richard Aspinall, Andrew Fowell, Joanna Dowman, Valério Nobili, Giovanni Targher, Nathalie M. Delzenne, Laure B. Bindels, Philip C. Calder, Christopher D. Byrne   +25 more
openalex   +2 more sources

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

Advanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha, Sofya Kosmynina, Amandine Verocq, Keremsah Ozen, Ines Tekia, Hugo Bussy, Marie Ramirez, Dima Sabbah, Chloe Goemans, Valerie Vandenbempt, Esteban N. Gurzov, Sumeet Pal Singh, Nicolas Baeyens   +12 more
wiley   +1 more source

Hepatoprotective effects of silybin in liver fibrosis. [PDF]

World J Gastroenterol
Liu XX, Hassan W, Ahmed H, Song SZ.
europepmc   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

Hepatocyte-hepatic stellate cell interactions in liver fibrosis: Mechanisms and therapeutic implications. [PDF]

Hepatol Commun
Wang Z, Cao Z, Dong Y, Hong Y, Zuo L, Wang H.   +5 more
europepmc   +1 more source