Results 111 to 120 of about 1,429,832 (378)

Automatic 3D Liver Segmentation Using Sparse Representation of Global and Local Image Information via Level Set Formulation [PDF]

arXiv, 2015
In this paper, a novel framework for automated liver segmentation via a level set formulation is presented. A sparse representation of both global (region-based) and local (voxel-wise) image information is embedded in a level set formulation to innovate a new cost function.
arxiv  

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

Molecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha, Steven Kao, Veronica K. Cheung, Wendy A. Cooper, Nico van Zandwijk, John E. J. Rasko, Dannel Yeo   +6 more
wiley   +1 more source

Similar reduction of cholesterol-adjusted Vitamin E serum levels in simple steatosis and non-alcoholic steatohepatitis [PDF]

, 2015
OBJECTIVES: Reduced vitamin E levels have been reported in patients with non-alcoholic steatohepatitis (NASH), but no conclusive data on patients with simple steatosis (SS) are available. Aim of this study was to investigate the association betweenserum
Angelico, Francesco, Baratta, Francesco, Bucci, Tommaso, Cangemi, Roberto, Carnevale, Roberto, DEL BEN, Maria, Labbadia, Giancarlo, Nocella, Cristina, Pani, Arianna, Pastori, Daniele, Pignatelli, Pasquale, Polimeni, Licia, Scardella, Laura, Violi, Francesco   +13 more
core   +1 more source

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini, Ezgi Oner, Mark P. Ward, Sinead Hurley, Brian David Henderson, Faye Lewis, Stephen P. Finn, Gerard J. Fitzmaurice, John J. O'Leary, Sharon O'Toole, Lorraine O'Driscoll, Kathy Gately   +11 more
wiley   +1 more source

Acute Fatty Liver of Pregnancy in a Taiwanese Tertiary Care Center: A Retrospective Review [PDF]

, 2010
SummaryObjectiveTo evaluate the demographics, clinical presentations, laboratory findings, and maternal and fetal outcomes in patients with acute fatty liver of pregnancy.Materials and MethodsA retrospective review was conducted of the records of ...
Chen, Chen-Yu, Chen, Chie-Pein, Chen, Yi-Yung, Huang, Jian-Pei, Lau, Hui-Hsuan, Su, Tsung-Hsien   +5 more
core   +2 more sources

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Relationship between liver function tests and thyroid hormones in thyroid disorders

Nigerian Postgraduate Medical Journal, 2013
Aims and Objectives: To evaluated the effect of thyroid dysfunction on liver function tests and if there is any correlation between them. Materials and methods: A total of 68 subjects (40 hyperthyroid and 28 hypothyroid) between the ages of 20-60 years ...
M O Ajala, P S Ogunro, O A Fasanmade
doaj  

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

Molecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu, Jinqiu Li, Junqi Ma, Ayshamgul Hasim   +3 more
wiley   +1 more source

Liver function tests in acute hepatitis in children [PDF]

, 2016
Background: Aim of study to analyse the elevation of liver enzymes of icteric children presenting as acute hepatitis and observe its association with hepatitis B surface antigen positivity rate.
., Shweta, Prasad, Rajiv Ranjan
core   +3 more sources

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source