Results 131 to 140 of about 1,429,832 (378)
Are liver function tests required for patients taking isoniazid for latent TB? [PDF]
Routine liver function test monitoring is not required for all patients on isoniazid therapy for latent tuberculosis (TB) infection (strength of recommendation: B, based on case series). No clinical trials have studied the potential risks and benefits of
Brown, Maureen O'Reilly, Howard, Ellen
core
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin+14 more
wiley +1 more source
Weil's Disease, with Tests for Liver Function [PDF]
F. E. d. W. Cayley
openalex +1 more source
Role of liver function tests among pregnant women with respect to feto-maternal outcome in third trimester: an analytical cross-sectional study [PDF]
Background: Liver disease occurs in approximately 3% of pregnant women so it has adverse effect on feto-maternal outcome. Diseases specifically related to pregnancy are intra-hepatic cholestasis of pregnancy, acute fatty liver of pregnancy, abnormal ...
Lal, Pavika+3 more
core +2 more sources
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita+1 more
wiley +1 more source
Liver Function Tests During the Perinatal Period
Summary: Serum iso-citrate dehydrogenase (ICD), aspartate transaminase (AST), alkaline phosphatase (ALP) gamma-glutamyli deter transferase (GGT), total bilirubin, total protein and albumin were deter mined and compared in 68 paired maternal and ...
Onwuameze IC..
doaj
LABRAD : Vol 36, Issue 1 - January 2011 [PDF]
Routine and Special Liver Function Tests Management of Coagulopathy Associated with Liver Disease Significance of Clinical and Laboratory Scoring System in Diagnosis of Disseminated Intravascular Coagulation in Chronic Liver Disease Laboratory Diagnosis ...
Aga Khan University Hospital, Karachi
core +1 more source
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi+5 more
wiley +1 more source
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park+6 more
wiley +1 more source