Results 131 to 140 of about 828,517 (357)

Flexible combination of multiple diagnostic biomarkers to improve diagnostic accuracy

open access: yes, 2015
In medical research, it is common to collect information of multiple continuous biomarkers to improve the accuracy of diagnostic tests. Combining the measurements of these biomarkers into one single score is a popular practice to integrate the collected ...
Fang, Yixin   +3 more
core   +1 more source

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

open access: yesMolecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva   +5 more
wiley   +1 more source

Liver Function Tests During the Perinatal Period

open access: yesNigerian Journal of Paediatrics
Summary: Serum iso-citrate dehydrogenase (ICD), aspartate transaminase (AST), alkaline phosphatase (ALP) gamma-glutamyli deter transferase (GGT), total bilirubin, total protein and albumin were deter mined and compared in 68 paired maternal and ...
Onwuameze IC..
doaj  

Functional evaluation of hepatic parenchyma with dynamic tests (Indocyanine green and Hippurate ratio) in patients with HCC [PDF]

open access: yes, 2011
Our aim was to assess hepatic functionality in patients with HCC and candidate for liver resection. We used dynamic tests of liver functionality Indocyanine green (ICG) and Hippurate ratio, for the evaluation of surgical risk and postoperative clinical
PETRACCIA, LUISA
core  

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

open access: yesMolecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima   +6 more
wiley   +1 more source

Clinical profile and liver function assessment in children with typhoid fever

open access: yesZdorovʹe Rebenka
Background. Typhoid fever is still a major health problem in developing countries, with significant morbidity and mortality. The disease can lead to liver damage if not adequately treated.
Ahmed Abdul Hadi Mohsen   +3 more
doaj   +1 more source

G-CSF mobilized PBMCs contribute to the liver function of cirrhotic rats [PDF]

open access: yes, 2010
On the basis of the recently recognized potential of bone marrow stem cells to give rise to hepatocytes, we here investigated the role of G-CSF priming PBMCs played in the liver of cirrhotic rats.
Wang, Su zhen   +3 more
core  

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