Results 61 to 70 of about 494,521 (299)

Kidney and Liver Predictors of Adults Hospitalized with COVID-19 Infection

open access: yesCOVID
SARS-CoV-2 damages not only the lungs, but also the liver and kidney. Most critically ill COVID-19 patients have liver and kidney dysfunctions. The early identification of patients with COVID-19 who will develop severe or critical disease symptoms is ...
Mariana Boulos   +5 more
doaj   +1 more source

Profound decrease of liver maximum function capacity test of isoflurane sedated patients: A report of three cases [PDF]

open access: gold, 2021
Elke Schwier   +5 more
openalex   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Association of serum 25-hydroxyvitamin D Levels and liver enzymes in a nationally representative sample of iranian adolescents: The childhood and adolescence surveillance and prevention of adult noncommunicable disease study

open access: yesInternational Journal of Preventive Medicine, 2018
Background: Hypovitaminosis D is highly prevalent and has several adverse health effects. This study aims to assess the relationship of serum concentrations of 25-hydroxyvitamin D (25[OH] D) and liver enzymes in adolescents.
Maryam Bahreynian   +5 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Relationship between liver function tests and thyroid hormones in thyroid disorders

open access: yesNigerian Postgraduate Medical Journal, 2013
Aims and Objectives: To evaluated the effect of thyroid dysfunction on liver function tests and if there is any correlation between them. Materials and methods: A total of 68 subjects (40 hyperthyroid and 28 hypothyroid) between the ages of 20-60 years ...
M O Ajala, P S Ogunro, O A Fasanmade
doaj  

Liver function tests: indication and interpretation [PDF]

open access: bronze, 2022
J Callen   +99 more
openalex   +1 more source

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