Results 51 to 60 of about 951,728 (296)

Hepatocyte-Derived Exosomes Reduce Hepatic Ischemia-Reperfusion (IR) Injury by Inhibiting Complement Activation

Frontiers in Bioscience-Landmark
Background: Exosomes are specialized secreted vesicles for intercellular communication and signaling pathways as specialized secreted vesicles.
Zhi Yang, Bin Deng, Tian Sun, Yongqin Wang, Wei Dong, Junfei Jin, Zhixiong Pan   +6 more
doaj   +1 more source

Imaging of High‐Risk Neuroblastoma: Recommendations From SIOPEN Radiology and Nuclear Medicine Specialty Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neuroblastoma is the most common extracranial solid tumor in early childhood. Its clinical behavior is highly variable, ranging from spontaneous regression to fatal outcome despite intensive treatment. The International Society of Pediatric Oncology Europe Neuroblastoma Group (SIOPEN) Radiology and Nuclear Medicine Specialty Committees ...
Annemieke Littooij, Catia Olianti, Herve Brisse, Pier Luigi Di Paolo, Maria Garganese, Tejas Kapadia, Jurgen Schaefer, Hugh Wallace, Simon Wan, Bart de Keizer, Irmina Sefic Pasic, Julian Rogasch   +11 more
wiley   +1 more source

Imaging Features and Interventional Treatment for Liver Injuries and Their Complications

대한영상의학회지, 2021
Liver injury is a common consequence of blunt abdominopelvic trauma. Contrast-enhanced CT allows for the rapid detection and evaluation of liver injury. The treatment strategy for blunt liver injury has shifted from surgical to nonoperative management,
Sung Hyun Yu, So Hyun Park, Jong Woo Kim, Jeong Ho Kim, Jung Han Hwang, Suyoung Park, Ki Hyun Lee   +6 more
doaj   +1 more source

Severe liver trauma among pediatric patients in the Japan Trauma Registry

World Journal of Pediatric Surgery, 2021
Background Limited information exists regarding the clinical characteristics, management practices, and outcomes of pediatric patients with liver injury in Japan.
Kiyohiro Oshima, Makoto Aoki, Toshikazu Abe, Shuichi Hagiwara, Daizoh Saitoh   +4 more
doaj   +1 more source

Dose-related liver injury of Geniposide associated with the alteration in bile acid synthesis and transportation. [PDF]

, 2017
Fructus Gardenia (FG), containing the major active constituent Geniposide, is widely used in China for medicinal purposes. Currently, clinical reports of FG toxicity have not been published, however, animal studies have shown FG or Geniposide can cause ...
Feng, Xiaoyi, Gao, Yue, Han, Jiayin, La Frano, Michael R, Li, Chunying, Li, Guiqin, Li, Xiaolong, Liang, Aihua, Liu, Jing, Newman, John W, Pan, Chen, Tian, Jingzhuo, Wang, Lianmei, Xiang, Shixie, Yi, Yan, Zhang, Yushi, Zhao, Yong, Zhu, Jingjing   +17 more
core   +2 more sources

Exploring Preferences for a Digital Single‐Session Intervention for Adolescent Siblings of Youth With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Adolescent siblings of children with cancer are at elevated risk for psychosocial problems. Unfortunately, various barriers such as limited family time and resources, conflicting schedules, and psychosocial staffing constraints at cancer centers hinder sibling access to support.
Christina M. Amaro, Sarah Silver, Prishi Patel, Meredith K. Reffner Collins, Kimberly S. Canter, Stephanie Fooks‐Parker, Michael Amylon, Shawna V. Hudson, Jessica L. Schleider, Melissa A. Alderfer, Katie A. Devine   +10 more
wiley   +1 more source

Lipid peroxidation is a nonparenchymal cell event with reperfusion after prolonged liver ischemia [PDF]

, 1990
A proposed mechanism for irreversible ischemic liver damage has been peroxidation of membrane phospholipids by free radicals. However, the hepatocyte is laden with enzymes which are antioxidants and, therefore, ought to be relatively resistant to ...
Makowka, L, Rao, PN, Starzl, TE, Walsh, TR   +3 more
core   +1 more source

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy, Elizabeth L. Seashore, W. Susan Cheng, Shondra Clay, Jessica A. Casas, Jennifer H. Foster   +5 more
wiley   +1 more source

Myocardial injury is a risk factor for 6-week mortality in liver cirrhosis associated esophagogastric variceal bleeding

Scientific Reports, 2023
This study sought to investigate risk factors for 6-week mortality of patients with decompensated liver cirrhosis associated esophagogastric variceal bleeding (EGVB) and clinical characteristics of myocardial injury in cirrhotic patients with EGVB.
Bihan Liu, Qi Li, Huiguo Ding, Shanshan Wang, Lifang Pang, Lei Li   +5 more
doaj   +1 more source

Gut–Liver Axis: Liver Sinusoidal Endothelial Cells Function as the Hepatic Barrier in Colitis-Induced Liver Injury

Frontiers in Cell and Developmental Biology, 2021
BackgroundBased on the gut–liver axis theory, a leaky gut can aggravate liver injury. However, clinical studies suggest that although gut mucosa damage is commonly observed in inflammatory bowel disease (IBD), it seldom leads to severe liver injury.
Yang Wang, Yang Wang, Yifan Zhang, Yifan Zhang, Yun Liu, Yun Liu, Jun Xu, Jun Xu, Jun Xu, Yulan Liu, Yulan Liu   +10 more
doaj   +1 more source