Results 81 to 90 of about 983,846 (346)

Author Response to Letters on the Manuscript “Herbal Immune Booster-Induced Liver Injury in the COVID-19 Pandemic – A Case Series” [PDF]

, 2021
Aabha Nagral, Omkar S. Rudra, Kunal Adhyaru, Amit Gharat, Sonal Bhandare   +4 more
openalex   +1 more source

Loss of ATF3 exacerbates liver damage through the activation of mTOR/p70S6K/ HIF-1α signaling pathway in liver inflammatory injury. [PDF]

, 2018
Activating transcription factor 3 (ATF3) is a stress-induced transcription factor that plays important roles in regulating immune and metabolic homeostasis.
Jiang, Bin, Jiang, Longfeng, Ke, Bibo, Li, Changyong, Lu, Ling, Ni, Xuhao, Wang, Han, Wang, Xuehao, Zhang, Feng, Zhu, Qiang   +9 more
core   +2 more sources

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Nutlin-3 promotes HBV replication by activating mTOR-mediated autophagy

Acta Virologica
BackgroundCurrently, there are approximately 240 million individuals worldwide suffering from chronic hepatitis B infection, yet a definitive cure remains elusive.
Shaowei Han, Yuanyuan Li, Junnan Wang, Yong Zhang, Yong Zhang, Yong Zhang, Yong Zhang   +6 more
doaj   +1 more source

Kv7-channel Blockage Reduces Liver Ischemia-reperfusion Injury in Mice [PDF]

, 2023
Johanna Ollesky, Marcella Steffani, Carolin Mogler, Fabian Stöcker, Volker Aßfalg, Helmut Frieß, Norbert Hüser, Daniel Hartmann   +7 more
openalex   +1 more source

A single heterochronic blood exchange reveals rapid inhibition of multiple tissues by old blood. [PDF]

, 2016
Heterochronic parabiosis rejuvenates the performance of old tissue stem cells at some expense to the young, but whether this is through shared circulation or shared organs is unclear.
Causey, Keith, CONBOY, Irina M, Conboy, Michael, Gathwala, Ranveer, Liu, Yan, Mehdipour, Melod, Rebo, Justin   +6 more
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

[Liver injuries].

Acta chirurgica Iugoslavica, 2011
The liver is the most commonly injured abdominal organ. Severe hepatic trauma continue to be associated with high mortality. Management of liver injuries has changed significantly over the last two decades. Nonoperative management of hemodynamically stable patients has become the first treatment of choice.
Aleksandar R, Karamarkovi, Kristina, Doklestić, Vladimir R, Djukić, Branislav D, Stefanović, Dejan V, Radenković, Pavle D, Gregorić, Nenad D, Ivancević, Zeljko D, Lausević, Nada M, Popović, Djordje D, Bajec   +9 more
openaire   +2 more sources

Intravital multiphoton microscopy can model uptake and excretion of fluorescein in hepatic ischemia-reperfusion injury [PDF]

, 2013
The liver is important in the biotransformation of various drugs, where hepatic transporters facilitate uptake and excretion. Ischemia-reperfusion (I/R) injury is a common occurrence in liver surgery, and the developing oxidative stress can lead to graft
Burczynski, Frank J., Fletcher, Linda M., Liu, Xin, Roberts, Michael S., Sanchez, Washington Y., Thorling, Camilla A.   +5 more
core   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source