Results 11 to 20 of about 27,503 (167)
Fate of linoleic, arachidonic, and docosa-7,10,13,16-tetraenoic acids in rat testicles
Journal of Lipid Research, 1973 A comparative study was made on the fate of linoleic, arachidonic, and docosa-7,10,13,16-tetraenoic acids in various subcellular fractions of liver and testis from rats of different ages.
Sixta Ayala +4 more
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Species Differences in Stereoselective Pharmacokinetics of HSG4112, A New Anti-Obesity Agent
Pharmaceutics, 2020 HSG4112, a racemic drug, is a new anti-obesity agent. In this study, the stereoselective pharmacokinetics of HSG4112 were investigated in rats and dogs, and the underlying mechanism was investigated. The plasma concentrations of HSG4112(S) and HSG4112(R)
In Yong Bae +5 more
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Microsomal Esterase of Rat Liver
Journal of Biological Chemistry, 1969 Abstract Rat liver microsomal esterase has been purified 254-fold by a combination of solubilization in a mechanical cell homogenizer, acetone and ammonium sulfate precipitations, and hydroxylapatite column chromatography. The enzyme hydrolyzed glyceryl 1-monodecanoate at a rapid rate; the Km is 1.61 x 10-3 m.
K, Hayase, A L, Tappel
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EFFECT OF TRYPSIN ON LIVER MICROSOMES [PDF]
The Journal of Cell Biology, 1963 The effect of trypsin on the morphology of the rat liver microsomal fraction isolated by differential centrifugation has been investigated. The microsomes were incubated at 37°C and centrifuged thereafter under the conditions of their initial isolation.
J, LUST, P, DROCHMANS
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Toxicology Reports, 2015 Terminalia arjuna is a tree having an extensive medicinal potential in cardiovascular disorders. Triterpenoids are mainly responsible for cardiovascular properties. Alcoholic and aqueous bark extracts of T.
Alice Varghese +3 more
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Nucleotide Activation of Liver Microsomal Glucuronidation
Journal of Biological Chemistry, 1961 6 páginas en ...
Pogell, Burton M., Leloir, Luis Federico
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Journal of Traditional Chinese Medical Sciences, 2019 Objective: To explore the glucuronic acid metabolism of acacetin in human liver and intestinal microsomes to better characterize human uridine 5′-diphospho (UDP)-glucuronosyltransferase (UGT) isoforms. In addition, interspecies comparisons were performed
Kangle Shi, Shan Li, Qinggang Meng
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Qualification of Human Liver Microsomes for Antibacterial Activity Screening of Drug Metabolites
Applied Microbiology, 2023 Microsomes are commonly used to perform in vitro drug metabolism, predominantly to form phase I drug metabolites. Pooled microsomes from multiple donors can contain microorganisms from underlying microbial diseases.
Navid Jubaer
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Dataset from proteomic analysis of human liver, lung, kidney and intestine microsomes
Data in Brief, 2018 We provide detailed datasets from our analysis of proteins that are identified in human liver, lung, kidney and intestine microsomes by MS-based proteomics.
Wei Song, Longjiang Yu, Zhihong Peng
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Regulation of hydroxymethylglutaryl-CoA reductase in rat leukocytes
Journal of Lipid Research, 1977 Methods were developed for the assay of hydroxymethylglutaryl-CoA reductase (NADPH) activity in microsomes from rat leukocytes. The activity in freshly isolated leukocytes is low compared to rat liver but can be assayed reliably. The patterns of response
N L Young, V W Rodwell
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