Results 51 to 60 of about 27,503 (167)

Radiation inactivation analysis of acyl-CoA:retinol acyltransferase and lecithin:retinol acyltransferase in rat liver

Journal of Lipid Research, 1993
Microsomes from liver and several other tissues esterify retinol through both fatty acyl-CoA-dependent and -independent reactions. Two activities, acyl-CoA:retinol acyltransferase (ARAT) and lecithin:retinol acyltransferase (LRAT) activities, have been ...
AC Ross, ES Kempner
doaj   +1 more source

Hepatic acylcoenzyme A: cholesterol acyltransferase activity during diet-induced hypercholesterolemia in cynomolgus monkeys.

Journal of Lipid Research, 1981
Acylcoenzyme A: cholesterol acyltransferase (ACAT) activity was studied in hepatic microsomes of cynomolgus monkeys fed either commercial chow or an atherogenic diet of high cholesterol and saturated fat content.
S N Mathur, M L Armstrong, C A Alber, A A Spector   +3 more
doaj   +1 more source

Purification and properties of a cholesteryl ester hydrolase from rat liver microsomes

Journal of Lipid Research, 1999
This report describes a purification procedure for a cholesteryl ester hydrolase (CEH) from female rat liver microsomes, and some structural, immunological, kinetic, and regulatory properties of the enzyme that distinguish the microsomal CEH from other ...
Susana Cristóbal, Begoña Ochoa, Olatz Fresnedo   +2 more
doaj   +1 more source

Inhibition of rat microsomal lipid peroxidation by the oral administration of D002

Brazilian Journal of Medical and Biological Research, 2000
The effect of D002, a defined mixture of higher primary alcohols purified from bee wax, on in vivo and in vitro lipid peroxidation was studied. The extent of lipid peroxidation was measured on the basis of the levels of thiobarbituric acid reactive ...
Menéndez R., Amor A.M., González R.M., Jiménez S., Más R.   +4 more
doaj  

Clofibric Acid Increases the Formation of Oleic Acid in Endoplasmic Reticulum of the Liver of Rats

Journal of Pharmacological Sciences, 2011
.: The effects of 2-(4-chlorophenoxy)-2-methylpropionic acid (clofibric acid) on the formation of oleic acid (18:1) from stearic acid (18:0) and utilization of the 18:1 formed for phosphatidylcholine (PC) formation in endoplasmic reticulum in the liver ...
Akihiko Hirose, Tohru Yamazaki, Takeshi Sakamoto, Katsuyoshi Sunaga, Tadashi Tsuda, Atsushi Mitsumoto, Naomi Kudo, Yoichi Kawashima   +7 more
doaj   +1 more source

Prediction of Hepatic Clearance of Stereoselective Metabolism of Carvedilol in Liver Microsomes and Hepatocytes of Sprague-Dawley and Cytochrome P450 2D-Deficient Dark Agouti Rats

Journal of Pharmacy & Pharmaceutical Sciences, 2019
Hepatic clearance (CLh) of carvedilol (CAR), which is eliminated via stereoselective metabolism by the CYP2D subfamily of cytochromes P450 (CYPs), was predicted using liver microsomes and hepatocytes from Sprague-Dawley (SD) rats and CYP2D-deficient Dark
Masahiro Iwaki, Toshiro Niwa, Hiroyuki Tanaka, Atsushi Kawase, Hiroshi Komura   +4 more
doaj   +1 more source

CL 277,082: a novel inhibitor of ACAT-catalyzed cholesterol esterification and cholesterol absorption.

Journal of Lipid Research, 1989
CL 277,082 (I) was found to be a potent inhibitor of acyl CoA:cholesterol acyltransferase (ACAT, EC 2.3.1.26) in microsomes from a variety of tissues with IC50 values of 0.14 microM for intestinal mucosal microsomes, 0.74 microM for liver, and 1.18 ...
E E Largis, C H Wang, V G DeVries, S A Schaffer   +3 more
doaj   +1 more source

Preclinical metabolism and metabolic drug–drug interaction profile of pedunculoside and rotundic acid

Clinical and Translational Science
Pedunculoside and rotundic acid, the most abundant components in plants of the genus Ilex L. (Aquifoliaceae), exhibit biological and pharmacological significance in the treatment of cardiovascular diseases.
Liang Wu, Linling Dong, Zhu Zhou, Xin Wang, Yujie Lin, Xuesong Shi, Peijing Wang, Suocheng Xu, Zhiyi Fang   +8 more
doaj   +1 more source

Inhibitory mechanism of vortioxetine on CYP450 enzymes in human and rat liver microsomes. [PDF]

Front Pharmacol, 2023
Zhan Y, Wang A, Yu Y, Chen J, Xu X, Nie J, Lin J.   +6 more
europepmc   +1 more source

liver-kidney microsomal antibodies

Citation: 'liver-kidney microsomal antibodies' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13392 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for ...
openaire   +1 more source