Results 241 to 250 of about 271,840 (313)

Triggering Mechanisms of Hepatocyte Repopulation during Liver Regeneration. [PDF]

Biomol Ther (Seoul)
Lee EJ, Lee NY, Choi MG, Ryu HJ, Koo JH.
europepmc   +1 more source

Tunable 3D‐Printed Static Mixers for Gradient Bioprinting With High Cell Viability

Advanced Materials Technologies, EarlyView.
ABSTRACT The fabrication of native tissue‐like structures with gradual transitions in material properties, cell types, and growth factors remains a major challenge in biofabrication due to the lack of suitable methods. Mimicking the hierarchical organization of living tissues is essential for functional models, yet creating gradient, multimaterial ...
Florian Hofmann, Jessica Faber, Franz Moser, Alessandro Cianciosi, Nicoletta Murenu, Joachim Schenk, Katrin G. Heinze, Natascha Schaefer, Silvia Budday, Tomasz Jungst   +9 more
wiley   +1 more source

Single-nucleotide human disease mutation inactivates a blood-regenerative GATA2 enhancer [PDF]

, 2019
Bresnick, Emery H, Cao, Miao, Choi, Kyunghee, Hofmann, Inga, Johnson, Kirby D, Keles, Sunduz, Liu, Peng, Mahta, Charu, Soukup, Alexandra A, Wu, Jun, Zhang, Jing, Zheng, Ye, Zhou, Yun   +12 more
core   +1 more source

Role of mitogens in normal and pathological liver regeneration. [PDF]

Hepatol Commun
Vosough M, Shokouhian B, Sharbaf MA, Solhi R, Heidari Z, Seydi H, Hassan M, Devaraj E, Najimi M.   +8 more
europepmc   +1 more source

An Accessible Microfluidic Platform for the Generation of Polarized Brain Organoids

Advanced Materials Technologies, EarlyView.
This study presents an accessible double‐gradient microfluidic device that enables controlled morphogen delivery and spatially polarized differentiation in brain organoids. By integrating a pump‐free design and stable fabrication method, the platform generates dorsal–ventral neuronal asymmetry, offering a reproducible and versatile approach to model ...
Daniel Pérez‐Calixto, Manuel Alejandro Vazquez Valle, Mitzi Pérez‐Calixto, Cindy Peto‐Gutiérrez, Iván Velasco, Genaro Vázquez‐Victorio, Itzel Escobedo‐Avila   +6 more
wiley   +1 more source

SLC1A5-dependent glutamine uptake in hepatocytes promotes liver regeneration. [PDF]

Hepatol Commun
Duan Y, Peng S, Yue J, Ding F, Chen X, Pan W, Gao X, Pang P, Zhang Y, Wu W, Schneider KM, Cubero FJ, Trautwein C, Zhang L, Zhang Y, Liu J, Zhao G.   +16 more
europepmc   +1 more source

Additive‐Manufactured, Multifunctional Bioreactor Technology for Dynamic Culture of 3D Bioprinted Tissue Models

Advanced Materials Technologies, EarlyView.
We introduce an additively manufactured bioreactor with a perfusion flow system and integrated temperature and pH sensors for skeletal muscle tissue biofabrication. The bioreactor's performance was evaluated by assessing the viability, spreading of the myoblast cells in a printed scaffold, and contraction of the isolated murine musculi interossei ...
Lys Sprenger, Johann Schorzmann, Hsuan‐Heng Lu, Muhammad Osama, Julian Bauer, Michael Haug, Oliver Friedrich, Aldo R. Boccaccini, Frank Döpper, Sahar Salehi   +9 more
wiley   +1 more source

Differential Effects of Liver Regeneration on Aging-Related Changes in Gene Expression and Metabolic Function. [PDF]

Aging Cell
Murayama R, Horisawa K, Miura S, Taniguchi S, Shu J, Takahashi M, Izumi Y, Bamba T, Ishigami K, Suzuki A.   +9 more
europepmc   +1 more source

AI‐Powered Framework for Evaluating Drug Efficacy for Three‐Dimensional In Vitro Cancer Models in Robot‐Assisted Production

Advanced Robotics Research, EarlyView.
An AI‐powered, robot‐assisted framework automatically produces, images, and analyzes 3D tumor spheroids to evaluate drug efficacy. Integrated modules handle spheroid formation, live/dead staining, brightfield imaging, and automated image analysis, including spheroid segmentation, viability and metrics to assess the drug treatment efficacy. The workflow
Dalia Mahdy, Jesus Nieves, Lukas Königer, Matthias Peindl, Fabio Erhard, Marc Möllmann, Anke Klingner, Markus Münig, Bibin Babu, Thomas Schwarz, Marco Metzger, Gudrun Dandekar, Maximiliane Wußmann, Jan Hansmann   +13 more
wiley   +1 more source

IMT504 accelerates post-hepatectomy liver regeneration in mice with involvement of GLAST + Wnt1 + bone marrow stromal progenitors. [PDF]

Sci Rep
Borda M, Cafaro L, Sierra R, Díaz Pedraza M, Becerra C, Ábalo A, Karolewski MJ, Cantero MJ, Schiavone M, Mazzolini GD, Montaner A, Fiore EJ, Aquino JB.   +12 more
europepmc   +1 more source