Results 221 to 230 of about 148,295 (267)
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Hepato-gastroenterology, 1988
Despite great advances in analysing hemodynamic, morphological and biochemical changes during the process of liver regeneration, the exact (patho)physiological mechanism is still unknown. A short survey of literature is given of the kinetics of liver regeneration and the significance of different hepatotrophic factors.
Chamuleau, R. A., Bosman, D. K.
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Despite great advances in analysing hemodynamic, morphological and biochemical changes during the process of liver regeneration, the exact (patho)physiological mechanism is still unknown. A short survey of literature is given of the kinetics of liver regeneration and the significance of different hepatotrophic factors.
Chamuleau, R. A., Bosman, D. K.
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Advances in liver regeneration
Expert Review of Gastroenterology & Hepatology, 2014Liver regeneration after partial hepatectomy is the only example of a regenerative process in mammals in which the organ/body weight ratio returns to 100% of the original when the process is complete. The adjustment of liver weight to the needs of the body suggests a complicated set of control points, a 'hepatostat'.
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Mechanosensing in liver regeneration
Seminars in Cell & Developmental Biology, 2017Liver is highly regenerative as it can restore its function and size even after 70% partial hepatectomy. During liver regeneration, the mechanical and chemical environment of liver is altered with accumulation of various growth factors and remodeling of extracellular environment. Cells can sense the changes in their cellular environment through various
Ziwei, Song +5 more
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Fibrinolysis and liver regeneration
Journal of Cellular Physiology, 1977AbstractThe plasmin and plasminogen activator proteases of the plasma fibrinolytic system were investigated as potential blood‐borne mediators of the proliferative activation of hepatocytes by partial hepatectomy. Partial (68%) liver resection, as well as proliferatively activating the remaining hepatocytes, rapidly (by 30 minutes) doubled the level ...
Rixon, R., Walker, P., Whitfield, James
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Augmenter of liver regeneration: A key protein in liver regeneration and pathophysiology
Hepatology Research, 2018Liver is constantly exposed to pathogens, viruses, chemicals, and toxins, and several of them cause injury, leading to the loss of liver mass and sometimes resulting in cirrhosis and cancer. Under physiological conditions, liver can regenerate if the loss of cells is less than the proliferation of hepatocytes. If the loss is more than the proliferation,
Parul, Gupta, Senthil Kumar, Venugopal
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Effects of octreotide on liver regeneration and tumour growth in the regenerating liver
Journal of Gastroenterology and Hepatology, 1997ABSTRACTThe ability of the liver to regenerate following resection is remarkable. However, there is evidence to suggest that tumour growth within the regenerating liver is significantly increased. As octreotide (a synthetic analogue of somatostatin) inhibits the growth and development of hepatic tumour in rats, we have investigated its effects on liver
N, Davies +4 more
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Microenvironment of liver regeneration in liver cancer
Chinese Journal of Integrative Medicine, 2017The occurrence and development of liver cancer are essentially the most serious outcomes of uncontrolled liver regeneration. The progression of liver cancer is inevitably related to the abnormal microenvironment of liver regeneration. The deterioration observed in the microenvironment of liver regeneration is a necessary condition for the occurrence ...
Han-Min, Li, Zhi-Hua, Ye
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Biomarkers in liver regeneration
Clinica Chimica ActaLiver regeneration is a complex and tightly regulated process essential for maintaining organ function following injury or surgical resection. This work explores the molecular mechanisms and key biomarkers involved in liver regeneration, highlighting their role in monitoring, predicting, and enhancing hepatic recovery. Conventional liver function tests,
Radjabov, Akhtam +12 more
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Liver regeneration, liver cancers and cyclins
Journal of Gastroenterology and Hepatology, 1998Accumulating evidence has revealed that malignant cell growth is regulated by complex mechanisms involved in genetic and epigenetic factors. Among human cancers, cancer in the liver (hepatocellular carcinoma (HCC)) is characterized by the evidence that it is usually based on chronic liver diseases such as liver cirrhosis or chronic hepatitis, in which ...
Tsuneo, Kitamura +2 more
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TGFβ Signaling in Liver Regeneration
Current Pharmaceutical Design, 2012Adult organ regeneration occurs in many systems such as in liver, skin, intestine and heart, indicating that postnatal life is not a static or quiescent state but a dynamic and complex process. The liver is a spectacular organ, exhibiting high regenerative capacity crucial for homeostasis and tissue repair: injuries induced mechanically or chemically ...
Karkampouna, S. +3 more
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