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Lineage Tracing Reveals the Bipotency of SOX9<sup>+</sup> Hepatocytes during Liver Regeneration. [PDF]
Stem Cell ReportsHan X +14 more
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Neutrophil and macrophage crosstalk might be a potential target for liver regeneration
Yiyuan Chen +8 more
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Liver regeneration-associated hepatocellular YAP1 activation prevents colorectal cancer liver metastasis through glutamine competition. [PDF]
Sci AdvYu Q +17 more
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Liver regeneration and liver metastasis
Seminars in Cancer Biology, 2021Surgical resection for primary and secondary hepatic neoplasms provides the best chance of cure. Advanced surgical techniques such as portal vein embolisation, two-staged hepatectomy and associated liver partition and portal vein ligation for staged-hepatectomy (ALPPS) have facilitated hepatic resection in patients with previously unresectable, bi ...
Georgina E, Riddiough +3 more
openaire +2 more sources
Science, 1997
Liver regeneration after the loss of hepatic tissue is a fundamental parameter of liver response to injury. Recognized as a phenomenon from mythological times, it is now defined as an orchestrated response induced by specific external stimuli and involving sequential changes in gene expression, growth factor production, and morphologic structure.
G K, Michalopoulos, M C, DeFrances
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Liver regeneration after the loss of hepatic tissue is a fundamental parameter of liver response to injury. Recognized as a phenomenon from mythological times, it is now defined as an orchestrated response induced by specific external stimuli and involving sequential changes in gene expression, growth factor production, and morphologic structure.
G K, Michalopoulos, M C, DeFrances
openaire +3 more sources
Journal of Hepatology, 2000
The liver can precisely regulate its growth and mass. Surgical resection of hepatic lobes or hepatocyte loss caused by viral or chemical injury triggers hepatocyte replication while enlarged liver mass is corrected by apoptosis. Hepatocytes have a great replicative capacity and are capable of repopulating the liver.
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The liver can precisely regulate its growth and mass. Surgical resection of hepatic lobes or hepatocyte loss caused by viral or chemical injury triggers hepatocyte replication while enlarged liver mass is corrected by apoptosis. Hepatocytes have a great replicative capacity and are capable of repopulating the liver.
openaire +2 more sources
Frontiers in Bioscience, 2002
Unlike other vital organs, the liver typically regenerates after injury. Indeed, the very factors that cause liver injury initiate a reparative process in the residual liver that includes the induction of cytoprotective mechanisms, deletion of mortally wounded cells, repair of less damaged survivors, liver cell proliferation to replace the cells that ...
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Unlike other vital organs, the liver typically regenerates after injury. Indeed, the very factors that cause liver injury initiate a reparative process in the residual liver that includes the induction of cytoprotective mechanisms, deletion of mortally wounded cells, repair of less damaged survivors, liver cell proliferation to replace the cells that ...
openaire +2 more sources
2023
Abstract The liver is the only mammalian organ capable of complete recovery following major tissue loss. Intense research has revealed the profound complexity behind liver regeneration, rightly considered to be one of the most intriguing processes within the human body.
Bostjan Humar, Rok Humar
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Abstract The liver is the only mammalian organ capable of complete recovery following major tissue loss. Intense research has revealed the profound complexity behind liver regeneration, rightly considered to be one of the most intriguing processes within the human body.
Bostjan Humar, Rok Humar
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Hepato-gastroenterology, 1988
Despite great advances in analysing hemodynamic, morphological and biochemical changes during the process of liver regeneration, the exact (patho)physiological mechanism is still unknown. A short survey of literature is given of the kinetics of liver regeneration and the significance of different hepatotrophic factors.
Chamuleau, R. A., Bosman, D. K.
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Despite great advances in analysing hemodynamic, morphological and biochemical changes during the process of liver regeneration, the exact (patho)physiological mechanism is still unknown. A short survey of literature is given of the kinetics of liver regeneration and the significance of different hepatotrophic factors.
Chamuleau, R. A., Bosman, D. K.
openaire +2 more sources