Results 271 to 280 of about 271,840 (313)
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Fibrinolysis and liver regeneration
Journal of Cellular Physiology, 1977AbstractThe plasmin and plasminogen activator proteases of the plasma fibrinolytic system were investigated as potential blood‐borne mediators of the proliferative activation of hepatocytes by partial hepatectomy. Partial (68%) liver resection, as well as proliferatively activating the remaining hepatocytes, rapidly (by 30 minutes) doubled the level ...
Rixon, R., Walker, P., Whitfield, James
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Augmenter of liver regeneration: A key protein in liver regeneration and pathophysiology
Hepatology Research, 2018Liver is constantly exposed to pathogens, viruses, chemicals, and toxins, and several of them cause injury, leading to the loss of liver mass and sometimes resulting in cirrhosis and cancer. Under physiological conditions, liver can regenerate if the loss of cells is less than the proliferation of hepatocytes. If the loss is more than the proliferation,
Parul, Gupta, Senthil Kumar, Venugopal
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Effects of octreotide on liver regeneration and tumour growth in the regenerating liver
Journal of Gastroenterology and Hepatology, 1997ABSTRACTThe ability of the liver to regenerate following resection is remarkable. However, there is evidence to suggest that tumour growth within the regenerating liver is significantly increased. As octreotide (a synthetic analogue of somatostatin) inhibits the growth and development of hepatic tumour in rats, we have investigated its effects on liver
N, Davies +4 more
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Biomarkers in liver regeneration
Clinica Chimica ActaLiver regeneration is a complex and tightly regulated process essential for maintaining organ function following injury or surgical resection. This work explores the molecular mechanisms and key biomarkers involved in liver regeneration, highlighting their role in monitoring, predicting, and enhancing hepatic recovery. Conventional liver function tests,
Radjabov, Akhtam +12 more
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Microenvironment of liver regeneration in liver cancer
Chinese Journal of Integrative Medicine, 2017The occurrence and development of liver cancer are essentially the most serious outcomes of uncontrolled liver regeneration. The progression of liver cancer is inevitably related to the abnormal microenvironment of liver regeneration. The deterioration observed in the microenvironment of liver regeneration is a necessary condition for the occurrence ...
Han-Min, Li, Zhi-Hua, Ye
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2023
Abstract The liver is the only mammalian organ capable of complete recovery following major tissue loss. Intense research has revealed the profound complexity behind liver regeneration, rightly considered to be one of the most intriguing processes within the human body.
Bostjan Humar, Rok Humar
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Abstract The liver is the only mammalian organ capable of complete recovery following major tissue loss. Intense research has revealed the profound complexity behind liver regeneration, rightly considered to be one of the most intriguing processes within the human body.
Bostjan Humar, Rok Humar
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Liver regeneration, liver cancers and cyclins
Journal of Gastroenterology and Hepatology, 1998Accumulating evidence has revealed that malignant cell growth is regulated by complex mechanisms involved in genetic and epigenetic factors. Among human cancers, cancer in the liver (hepatocellular carcinoma (HCC)) is characterized by the evidence that it is usually based on chronic liver diseases such as liver cirrhosis or chronic hepatitis, in which ...
Tsuneo, Kitamura +2 more
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TGFβ Signaling in Liver Regeneration
Current Pharmaceutical Design, 2012Adult organ regeneration occurs in many systems such as in liver, skin, intestine and heart, indicating that postnatal life is not a static or quiescent state but a dynamic and complex process. The liver is a spectacular organ, exhibiting high regenerative capacity crucial for homeostasis and tissue repair: injuries induced mechanically or chemically ...
Karkampouna, S. +3 more
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Bulletin of Experimental Biology and Medicine, 1962
Experiments were conducted on roosters aged 3 months. In the first series of tests the distal edge of the left lobe of the liver was removed at the level of its bifurcation, in the second, the distal edge of the right lobe, at the gall bladder level. The removed part constituted from 1/8 to 1/10 of the total weight of this organ.
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Experiments were conducted on roosters aged 3 months. In the first series of tests the distal edge of the left lobe of the liver was removed at the level of its bifurcation, in the second, the distal edge of the right lobe, at the gall bladder level. The removed part constituted from 1/8 to 1/10 of the total weight of this organ.
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Decellularized Liver Scaffold for Liver Regeneration
2017After being initially hailed as the ultimate solution to end-stage organ failure, such as end-stage liver disease (ESLD), engineering of vascularized tissues has stalled because of the need for a well-structured circulatory system that can maintain the cells to be seeded inside the construct.In the field of regenerative medicine, decellularized ...
Wei, Yang +4 more
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