Results 81 to 90 of about 154,170 (305)
Generating Cell Surface Nucleated Hydrogels with an Artificial Membrane‐Binding Transglutaminase
Advanced Functional Materials, EarlyView.Cell‐based therapies require advanced strategies to enhance cell delivery and bioactivity. Cell membrane engineering offers an avenue to impart new functions to delivered cells to boost their viability and function. Here, an artificial membrane‐binding transglutaminase is generated and biophysically characterized.
Rosalia Cuahtecontzi Delint +6 more
wiley +1 more source
Constructing a research model for liver regeneration by using hepatocyte-like organoid derived from human pluripotent stem cells [PDF]
Jichu yixue yu linchuangObjective To construct an in vitro research model for studying human liver regeneration based on human pluripotent stem cells (hPSCs)-derived hepatocyte-like organoid (HLO).
WANG Chenxi, YANG Shuchun, JIA Yuyan, HUANG Yue
doaj +1 more source
Advanced Functional Materials, EarlyView.An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu +14 more
wiley +1 more source
Advanced Functional Materials, EarlyView.A mechanically tunable hydrogel composed of gelatin, chondroitin sulfate and laminin promotes angiogenesis in vitro without the supplement of growth factors. Endothelial cells morphogenesis was further enhanced by medium conditioned with bioactive glass 58S‐released ions (Ca and Si), thus offering a promising strategy to vascularize 3D tissue ...
Marco Piazzoni +13 more
wiley +1 more source
Interconnected Porous Hydrogels with Tunable Anisotropy Through Aqueous Emulsion Bioprinting
Advanced Functional Materials, EarlyView.A 3D bioprintable microporous bioink is developed using an aqueous two‐phase system (ATPS) composed of extracellular matrix (ECM) mimetic biopolymers. The ATPS bioink enables the fabrication of interconnected porous architectures with up to 70% porosity, supporting long‐term cell viability and 3D cell alignment, enabling a simultaneous generation of ...
Hugo Edgar‐Vilar +4 more
wiley +1 more source
From Seeing to Simulating: A Survey of Imaging Techniques and Spatially-Resolved Data for Developing Multiscale Computational Models of Liver Regeneration [PDF]
, 2022 Aalap Verma +4 more
openalex +1 more source
Electrochemically Driven Dissipative Growth of Affinity Hydrogels for Bioresponsive Interfaces
Advanced Functional Materials, EarlyView.Voltage pulses drive the growth and reinforcement of hydrogel films under dissipative conditions. This biocompatible strategy enables efficient integration of affinity ligands into the hydrogel matrix, enhancing the selective capture of growth factors and allowing precise temporal control over their release, making them well‐suited as adaptive ...
Roberto Baretta, Marco Frasconi
wiley +1 more source
Adaptive 4D‐Printed Vascular Stents With Low‐Temperature‐Activated and Intelligent Deployment
Advanced Functional Materials, EarlyView.Microarchitected coronary artery stents were fabricated using a polycaprolactone (PCL)‐based shape memory polymer (SMP) composite via projection micro‐stereolithography (PµSL) 4D printing. By incorporating diethyl phthalate (DEP) as a plasticizer, the thermal transition temperature (Ttran) was modulated to about 37°C, enabling rapid and autonomous ...
Yannan Li +12 more
wiley +1 more source
SETDB1 promotes mammalian liver regeneration by stimulating cytokine CSF3 in hepatocytes
Cell ReportsSummary: Discovering mechanisms of regeneration holds great promise for advancing regenerative medicine. Non-histone modifications by epigenetic factors participate in important biological processes. Through in vivo CRISPR screening combined with partial
Xiao-Yan Huang +8 more
doaj +1 more source