Results 61 to 70 of about 156,790 (310)

The mystery of liver regeneration

British Journal of Surgery, 2002
Abstract Background Partial hepatectomy is the strongest stimulator of hepatic regeneration. The process of initiation and the control of the final size of the regenerated liver have been the subject of research for many years. A better understanding of this process and the effect of disease may allow
Court, F., Wemyss-Holden, S., Dennison, A., Maddern, G.   +3 more
openaire   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Factors Affecting Liver Regeneration in Donors’ Grafts in Living Donor Liver Transplant (LDLT). A Center Experience. [PDF]

Ain-Shams Journal of Surgery, 2016
  Background: Liver regeneration for donors’ graft in living donor liver transplantation (LDLT), is an example of liver regeneration in normal liver.
Yehia Attwa, Wael Mansy, Morsi Mohamed, Karim Boudjema, Magdy Amin   +4 more
doaj   +1 more source

Liver Regeneration after Liver Transplantation [PDF]

European Surgical Research, 2012
<b><i>Background/Purpose:</i></b> The liver has a remarkable capacity to regenerate after injury or resection. The aim of this review is to outline the mechanisms and factors affecting liver regeneration after liver transplantation.
A, Taki-Eldin, L, Zhou, H-Y, Xie, S-S, Zheng   +3 more
openaire   +2 more sources

Morphology of mitochondria and cell respiration,pt.1.

, 1960
To reveal the mechanism of liver damage by taking CCl4 the author observed the liver tissues from rats at 1.5, 5, 6, 10, 17, 20, and 22 hours after the CCl4 administration, both by light microscope and electron-microscope. 1. Light microscope observation
Haba, Kyoichi
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Implication for Bone Marrow Derived Stem Cells in Hepatocyte Regeneration after Orthotopic Liver Transplantation

International Journal of Hepatology, 2013
The liver has the outstanding ability to regenerate itself and restore parenchymal tissue after injury. The most common cell source in liver growth/regeneration is replication of preexisting hepatocytes although liver progenitor cells have been ...
N. Pilat, L. Unger, G. A. Berlakovich
doaj   +1 more source

Augmenter of liver regeneration [PDF]

Fibrogenesis & Tissue Repair, 2012
'Augmenter of liver regeneration' (ALR) (also known as hepatic stimulatory substance or hepatopoietin) was originally found to promote growth of hepatocytes in the regenerating or injured liver. ALR is expressed ubiquitously in all organs, and exclusively in hepatocytes in the liver. ALR, a survival factor for hepatocytes, exhibits significant homology
openaire   +2 more sources

Survivin is upregulated during liver regeneration in rats and humans and is associated with hepatocyte proliferation

, 2009
BACKGROUND:Survivin regulates cell division and inhibits apoptosis. Liver regeneration is a complex process involving both proliferation and apoptosis.
Bodo Levkau, Baba, Hideo A., Levkau, Bodo, Silvio Nadalin, Karen Von Wnuck Lipinski, Schmitz, Klaus J., Benesch, Alexandra, Hideo A. Baba, Atsushi Takeda, Georgios C. Sotiropoulos, Yanli Gu, Alexandra Benesch, Nobuakira Takeda, Jeremias Wohlschlaeger, Wohlschlaeger, Jeremias, Lang, Hauke, Takeda, Atsushi, Takeda, Nobuakira, Hauke Lang, Biglarnia, Ali-Reza, Gu, Yanli, Nadalin, Silvio, Klaus J. Schmitz, Sotiropoulos, Georgios C., von Wnuck Lipinski, Karen, Ali‐R Biglarnia   +25 more
core   +1 more source

Unaltered liver regeneration in post‐cholestatic rats treated with the fxr agonist obeticholic acid [PDF]

, 2021
In a previous study, obeticholic acid (OCA) increased liver growth before partial hepatectomy (PHx) in rats through the bile acid receptor farnesoid X‐receptor (FXR). In that model, OCA was administered during obstructive cholestasis.
Damink, S.W.M.O.; id_orcid, Lewis, MR, van Golen, Rowan F, de Haan, Lianne R, Gulik, TM, Lewis, M.R., van Gulik, Thomas M., Olde Damink, Steven W M, Joanne Verheij, van Golen, RF, van Golen, R.F., Heger, M. (Michal), Verheij, J, Olthof, Pim B., van Gulik, Thomas M, Verena Horneffer-van der Sluis, Beuers, U. (Ulrich), Frank G. Schaap, Beuers, Ulrich H. W., Schaap, F.G. (Frank), Pim B. Olthof, Michal Heger, de Haan, LR, Heger, Michal, Verheij, Joanne, Lewis, M.R. (Matthew R.), Rowan F. van Golen, van Golen, Rowan F., Beuers, UHW, Horneffer-van der Sluis, V., van Gulik, T.M., Damink, S.W.M.O., Lewis, Matthew R., Afd Pharmaceutics, Golen, R.F. (Rowan) van, Horneffer‐van der Sluis, Verena, Horneffer‐van der Sluis, V. (Verena), Gulik, T.M. (Thomas) van, Pharmaceutics, Horneffer-van der Sluis, Verena, Schaap, Frank G., de Haan, Lianne R., Schaap, FG, Olde Damink, S.W.M. (Steven), Lianne R. de Haan, Olthof, Pim, Heger, M, Beuers, U.H.W., Beuers, Ulrich H W, Horneffer, V, Olde Damink, Steven W. M., Verheij, J., Olthof, P.B. (Pim B.), Olthof, Pim B, de Haan, L.R., Heger, M., Steven W. M. Olde Damink, Schaap, Frank G, de Haan, L.R. (Lianne R.), Lewis, Matthew R, Verheij, J. (Joanne), Schaap, F.G., Thomas M. van Gulik, Matthew R. Lewis, Olde Damink, SWM, Sub Membrane Biochemistry & Biophysics, Olthof, P.B., Ulrich H. W. Beuers   +67 more
core   +1 more source