Results 101 to 110 of about 148,295 (267)

Conjugated Porphyrin Polymer With Superior Charge Transfer for Photodynamic‐Immunomodulatory Prevention of CIED Infection in Diabetes

Advanced Healthcare Materials, EarlyView.
Under NIR irradiation, PTCPP generates ROS to eliminate MRSA biofilms and promote M1 macrophage polarization for phagocytosis. After bacterial clearance, the material is phagocytosed by macrophages, shifting their polarization to M2 phenotype via metabolic reprogramming, which synergistically enhances anti‐infection therapy and wound healing.
Honghao Ma, Jinguo Xu, Rongrong Gu, Chuanhui Dong, Te Chen, Yi Mu, Jing Zhu, Yating Wang, Wen Wang, Yingying Zhang, Hongyu Ma, Xiaochen Wang, Sheng Ye, Cheng Cheng   +13 more
wiley   +1 more source

Multicomponent Peptide‐MXene‐Hyaluronic Acid Hydrogel as a Conductive Scaffold for Enhanced Fibroblast Proliferation and Migration Under Electrical Stimulation

Advanced Healthcare Materials, EarlyView.
An electrically conductive FmocFF/MXene/hyaluronic acid hydrogel combines extracellular matrix‐like architecture, self‐healing behavior, oxidation‐resistant conductivity, and biochemical cues in a single scaffold. By enabling physiologically relevant electrical stimulation, the platform enhances fibroblast attachment, proliferation, and migration ...
Offir Loboda, Dana Cohen‐Gerassi, Dor Aaron Goldstein, Or Messer, Bar Favelukis, Ehud Gazit, Maxim Sokol, Lihi Adler‐Abramovich   +7 more
wiley   +1 more source

Using different zebrafish models to explore liver regeneration

Frontiers in Cell and Developmental Biology
The liver possesses an impressive capability to regenerate following various injuries. Given its profound implications for the treatment of liver diseases, which afflict millions globally, liver regeneration stands as a pivotal area of digestive organ ...
Dashuang Mo, Mengzhu Lv, Xiaoyu Mao
doaj   +1 more source

A Fully Defined GelMA‐Based Matrix Allows Fine Tuning of Tissue‐Relevant Biomechanical and Biochemical Cues for Organoid Culture

Advanced Healthcare Materials, EarlyView.
A fully defined GelMA‐based ECM platform integrates tunable tissue‐relevant stiffness with laminin–entactin biochemical supplementation to support mouse small intestinal organoid growth. Coordinated control of mechanical and biochemical cues promotes robust proliferation, budding morphogenesis, differentiation, and passaging, providing a reproducible ...
Junyi Liu, Su Su Htwe, Lay Poh Tan, Yen Choo   +3 more
wiley   +1 more source

Wearable OLED‐Assisted Photodynamic Cancer Therapy Using Chlorin e6‐Loaded Pluronic Nanocapsules as Photosensitizers

Advanced Healthcare Materials, EarlyView.
A novel photodynamic therapeutic approach has been employed for anticancer therapy, utilizing chlorin e6‐loaded Pluronic nanocapsules and a wearable organic light‐emitting diode light source. This has shown significant in vivo antitumor efficacy with minimal off‐target toxicity. The innovative combination of a wearable light source and photosensitizers
Hyeryeon Oh, Seung Min Jeong, Cheol Hui Park, Panmo Son, Yeseo Lee, Heebeom Koo, Won Il Choi, Kyung Cheol Choi   +7 more
wiley   +1 more source

Shifting cell death modes in hepatic steatosis: from apoptosis to necroptosis

Endocrine Journal
In the liver, hepatocyte death occurs during the regeneration process following injury. While hepatocyte death triggers regeneration through hepatocyte proliferation in the non-steatotic liver, it impairs this process in the steatotic liver.
Yuka Inaba, Kohsuke Tsuchiya, Hiroshi Inoue   +2 more
doaj   +1 more source

Vascularization of Human iPSC‐Derived Kidney Organoids Using Perfusion Culture, Pre‐Vascularized Collagen Scaffolds, and Decellularized Extracellular Matrix

Advanced Healthcare Materials, EarlyView.
An integrated perfusion‐based culture platform combining pre‐vascularized collagen scaffolds, stromal vascular fraction cells, and kidney decellularized extracellular matrix promotes vascularization of human iPSC‐derived kidney organoids. The platform provides evidence of interactions between vascular networks and glomerular‐like structures and enables
Helen Kearney, Andrea Mazzoleni, Ivan Martin, Lorenzo Moroni, Manuele Giuseppe Muraro, Carlos Mota   +5 more
wiley   +1 more source

Multifunctional Thiolated Hyaluronic Acid‐graft‐PEDOT Dressing With Antifouling, On‐Demand Drug Delivery and Electrical Stimulation for Wound Healing

Advanced Healthcare Materials, EarlyView.
A multifunctional P(EDOT‐co‐EDOT‐g‐THA) dressing acts as a dynamic biointerface integrating antifouling capability, on‐demand drug delivery, and electrical stimulation. It achieves electrochemically triggered thiolated hyaluronic acid (THA) release while modulating cellular responses for wound healing application.
Jingwen Yang, Jiwon Hong, Anthony Phillips, Bicheng Zhu, Jenny Malmstrom, Devon T. Bryant, Alireza Akbarinejad, Lisa I. Pilkington, Jadranka Travas‐Sejdic   +8 more
wiley   +1 more source

Electroacupuncture Promotes Liver Regeneration by Activating DMV Acetylcholinergic Neurons‐Vagus‐Macrophage Axis in 70% Partial Hepatectomy of Mice

Advanced Science
Lack of liver regenerative capacity is the primary cause of hepatic failure and even mortality in patients undergoing hepatectomy, with no effective intervention strategies currently available.
Liu Yang, Yanyu Zhou, Zhaoshuai Huang, Wenxuan Li, Jiacheng Lin, Weifan Huang, Yali Sang, Fang Wang, Xuehua Sun, Jiangang Song, Hailong Wu, Xiaoni Kong   +11 more
doaj   +1 more source

Mechanotransduction of Magnetically Applied Forces Leads to Mechanical Stiffening of Platelet‐Rich Plugs

Advanced Healthcare Materials, EarlyView.
A microfluidic device with magnetic microposts was used to assess platelet mechanobiology. The oscillatory actuation of posts with embedded iron particles was dampened by the dynamic stiffening of the platelet‐rich plugs. This stiffening process increased with applied load, but inhibiting platelet activation (ASA) or myosin contractility (blebbistatin)
Nikita Taparia, Ava M. Obenaus, Yoeur‐Man T. Mach, Nakul Sridhar, Nathan J. Sniadecki   +4 more
wiley   +1 more source