Results 121 to 130 of about 156,790 (310)

Shaping Matter with Acoustic Waves: From Particles to Functional Structures

Advanced Functional Materials, EarlyView.
Acoustic‐directed assembly is reviewed as a materials‐oriented strategy for organizing particles, polymers, metals, and biological systems into functional structures. The review distinguishes reversible manipulation from permanent structure formation through medium fixation, particle fixation, and in situ material generation, highlighting routes toward
Avraham Kenigsberg, Shelly Zlotnikov, Maya Fiorentino, Yuval Elias, Ornit Nagler‐Avramovitz, Hagay Shpaisman   +5 more
wiley   +1 more source

Constructing a research model for liver regeneration by using hepatocyte-like organoid derived from human pluripotent stem cells [PDF]

Jichu yixue yu linchuang
Objective To construct an in vitro research model for studying human liver regeneration based on human pluripotent stem cells (hPSCs)-derived hepatocyte-like organoid (HLO).
WANG Chenxi, YANG Shuchun, JIA Yuyan, HUANG Yue
doaj   +1 more source

Coagulative Granular Hydrogels with an Enzyme Catalyzed Fibrin Network for Endogenous Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Coagulative granular hydrogels are composed of packed thrombin‐functionalized microgels that catalyze the conversion of fibrinogen into a secondary fibrin network, filling the interstitial voids. This bio‐inspired approach stabilizes the biomaterial to match the robustness of bulk hydrogels without compromising injectability, mimicking the initial ...
Zhipeng Deng, Camila B. Tovani, Simona Bianco, Gianni Comandini, Aya Elghajiji, Mina Aleemardani, Roxana Moscalu, Jeremie Zappia, Bianca Fernandes, Olivia Annett, Chrissy L. Hammond, Jason Wong, Dave J. Adams, Fabrizio Scarpa, Michael R. Whitehouse, Annela M. Seddon, James P. K. Armstrong   +16 more
wiley   +1 more source

Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels

Advanced Healthcare Materials, EarlyView.
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa, Lineta Stonkute, Sara Trujillo, Mariana Azevedo Gonzalez Oliva, Francis Burton, Matthew J. Dalby, Oana Dobre, Godfrey Smith, Manuel Salmeron‐Sanchez   +8 more
wiley   +1 more source

Role of liver progenitors in liver regeneration.

Hepatobiliary surgery and nutrition, 2015
During massive liver injury and hepatocyte loss, the intrinsic regenerative capacity of the liver by replication of resident hepatocytes is overwhelmed. Treatment of this condition depends on the cause of liver injury, though in many cases liver transplantation (LT) remains the only curative option.
Best, Jan, Manka, Paul, Syn, Wing-Kin, Dollé, Laurent, van Grunsven, Leo A, Canbay, Aliekber   +5 more
openaire   +3 more sources

Influence of Preoperative Chemotherapy on CT Volumetric Liver Regeneration Following Right Hemihepatectomy.

, 2014
BACKGROUND: An increasing number of patients undergo major liver resection following preoperative chemotherapy. Liver regeneration may be impaired in these patients, predisposing them to postoperative liver dysfunction.
de Boer, Marieke T.; id_orcid, Dello, S.A., van Gulik, T., Verhoef, Kees, de Boer, MT, Molenaar, Q, Verhoef, C., Dello, Simon A. W. G., Klaase, J. M., Kele, Petra G. Serbanescu, Bosscha, K, Klaase, Joost M., Molenaar, Quintus, van Dam, Ronald M., van Gulik, Thomas, van der Jagt, EJ, Dejong, CHC, Kele, P.G., van de Jagt, E.J., Dejong, C.H., Dejong, Cornelis H. C., de Boer, Marieke T., Molenaar, Q., van Dam, R.M., Dello, SAWG, van Gulik, T, Kele, PGS, van Dam, RM, de Boer, M. T., Verhoef, Cees, Porte, RJ, van der Jagt, Eric J., Klaase, JM, Bosscha, K., Bosscha, Koop, Porte, R.J., Porte, Robert J.   +36 more
core   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Co‐Electrospinning Extracellular Matrix with Polycaprolactone Enables a Modular Approach to Balance Bioactivity and Mechanics of a Multifunctional Bone Wrap

Advanced Healthcare Materials, EarlyView.
The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones, Madeline Laude, Zeenat Oyebanji, Ruchi Birur, Andres Luengo Martinez, Isabelle Gilbert, Phillip Baek, Nichole Longbottom, Nicole McCullough, Staci J. Horn, Chien‐Yu Lin, Matthew J. Lohr, Fred Clubb, Manuel K. Rausch, Elizabeth Cosgriff‐Hernandez   +14 more
wiley   +1 more source

SETDB1 promotes mammalian liver regeneration by stimulating cytokine CSF3 in hepatocytes

Cell Reports
Summary: Discovering mechanisms of regeneration holds great promise for advancing regenerative medicine. Non-histone modifications by epigenetic factors participate in important biological processes. Through in vivo CRISPR screening combined with partial
Xiao-Yan Huang, Dong Yang, Yin-Zhe Liu, En-Xiang Zhang, Qiao Yang, Wang Kang, Xiao-Ou Zhang, Junwei Shi, Chun-Qing Song   +8 more
doaj   +1 more source