Results 121 to 130 of about 148,295 (267)

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

open access: yesAdvanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Resolving Heterogeneity of Targeted Lipid Nanoparticles Through Solution‐Based Biophysical Analyses

open access: yesAdvanced Materials, EarlyView.
AF4‐UV‐DLS‐MALS‐SAXS resolves previously inaccessible targeted lipid nanoparticle (tLNP) subpopulations that differ in size, shape, and composition. Correlation of subpopulation‐resolved biophysical properties with in vivo RNA delivery reveals that targeted placental transfection is associated with distinct tLNP subpopulations rather than ensemble ...
Hannah C. Geisler   +14 more
wiley   +1 more source

Developing a Clinically Practical Biomaterial Platform for Endogenous Liver Regeneration. [PDF]

open access: yesGels
Beamish C   +15 more
europepmc   +1 more source

Boolean Logic‐Based Control Over Recombinant Protein Biomaterial Degradability and Therapeutic Delivery

open access: yesAdvanced Materials, EarlyView.
Fully recombinant protein‐based biomaterials execute complex Boolean logic for user‐programmable material degradation and concomitant therapeutic cargo release. Biologics, such as growth factors, can be incorporated within the crosslinkers as “drugamers”, while encapsulated cells can be released according to nested YES/OR/AND‐type logical operations ...
Murial L. Ross   +3 more
wiley   +1 more source

Dual control of liver regeneration by Nr1d1 homeostasis and Klf2 checkpoint. [PDF]

open access: yesCell Death Discov
Ye B   +8 more
europepmc   +1 more source

Recent Advances in Ferrite‐Based Materials for Biomedical Applications: A Comprehensive Review

open access: yesAdvanced Materials, EarlyView.
Ferrite nanoplatforms are presented as tunable biomedical materials in which synthesis control, cation engineering, defect/morphology regulation, and surface functionalization govern structure–property–bioactivity relationships. These design strategies enable multifunctional applications including MRI contrast, magnetic hyperthermia, targeted drug ...
Pramod D. Mhase   +6 more
wiley   +1 more source

Hyperpolarized MRI Detects Increased [1-<sup>13</sup>C]Pyruvate Metabolism in Early Liver Regeneration. [PDF]

open access: yesNMR Biomed
Kjærgaard U   +8 more
europepmc   +1 more source

Stimuli‐Responsive Hierarchical Structuring Controls Survival and Programs Hydrogelation of Supramolecular Metallofibers

open access: yesAdvanced Materials, EarlyView.
Aqueous Zn(II) Salphen metallofibers decorated with PNIPAM undergo reversible, multi‐stimuli‐responsive hierarchical bundling. This higher‐order structuring kinetically stabilizes the otherwise fragile assemblies against dilution, acidic hydrolysis, and transmetallation, enables selective sorting of responsive fibers, and programs hydrogelation at ...
Merlin R. Stühler   +5 more
wiley   +1 more source

The Extracellular Matrix in Liver Regeneration: Biological and Therapeutic Insights. [PDF]

open access: yesBioengineering (Basel)
Ma H   +10 more
europepmc   +1 more source

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