Results 111 to 120 of about 271,840 (313)

Tanshinone IIA attenuates hepatic stellate cell activation, oxidative stress, and liver fibrosis by inhibiting YAP signaling

European Journal of Histochemistry
Tanshinone IIA is derived from Salvia miltiorrhiza and has multiple therapeutic targets and functions. The exact therapeutic effects on liver fibrosis as well as the underlying hepatoprotective mechanisms are still lacking.
Dan Wang, Qingquan Tan, Qing Zheng, Yanling Ma, Li Feng   +4 more
doaj   +1 more source

The basis of liver regeneration: A systems biology approach

Annals of Hepatology, 2019
Introduction: Liver regeneration is a normal response to liver injury. The aim of this study was to determine the molecular basis of liver regeneration, through an integrative analysis of high-throughput gene expression datasets.
Mamatha Bhat, Elisa Pasini, Cristina Baciu, Marc Angeli, Atul Humar, Sonya Macparland, Jordan Feld, Ian McGilvray   +7 more
doaj   +1 more source

Changes of liver-resident NK cells during liver regeneration in rats [PDF]

, 1995
To determine the role of NK cells in regulation of tissue growth, the phenotype and function of liver-resident NK cells were studied after 70% partial hepatectomy in rats. The process of liver regeneration was generally completed by clay 14. In contrast,
Azzarone, A, Chambers, WH, Francavilla, A, Herberman, RB, Polimeno, L, Starzl, TE, Vujanovic, NL, Whiteside, TL   +7 more
core  

SLS Fabrication of Highly Porous Model Including Fine Flow Channel Network Aiming at Regeneration of Highly Metabolic Organs [PDF]

, 2006
Fabrication of very porous scaffold for regeneration of highly metabolic organs is reported. Polycaprolactone (PCL) powder was mixed with fine salt grains as filler and SLS processed to develop a model including fine flow channel network.
Huang, Hongyun, Naruke, Hiromichi, Niino, Toshiki, Sakai, Yasuyuki   +3 more
core   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Role of PINCH and Its Partner Tumor Suppressor Rsu-1 in Regulating Liver Size and Tumorigenesis [PDF]

, 2013
Particularly interesting new cysteine-histidine-rich protein (PINCH) protein is part of the ternary complex known as the IPP (integrin linked kinase (ILK)-PINCH-Parvin-α) complex.
Bhave, Vishakha S., Bowen, William C., Donthamsetty, Shashikiran, Haynes, Meagan M., Mars, Wendy M., Michalopoulos, George K., Orr, Anne, Singh, Shree Ram, Wu, Chuanyue   +8 more
core   +2 more sources

Stabilization of Miscible Aqueous Phases via Diffusion‐Controlled Multifunctional Nanoparticle‐Ligand Complexation

Advanced Functional Materials, EarlyView.
This study presents a versatile approach to harnessing miscible aqueous domains, enabling liquid‐in‐liquid compartmentalization using a barrier formed in situ rather than bulk immiscibility. The barrier forms upon the complexation of multifunctional nanoparticles and ligands at the contact boundary of aqueous phases.
Seyyed Alireza Hashemi, Mahyar Panahi‐Sarmad, Ahmadreza Ghaffarkhah, Vahid Rad, Masoud Soroush, Thomas P. Russell, Orlando J. Rojas, Mohammad Arjmand   +7 more
wiley   +1 more source

Molecular mechanisms controlling the phenotype and the EMT/MET dynamics of hepatocyte [PDF]

, 2014
The complex spatial and paracrine relationships between the various liver histotypes are essential for proper functioning of the hepatic parenchymal cells.
Fausto N, Lazarevich NL, Michelotti GA, Omenetti A, Spagnoli FM, Treyer A, Valdes F   +6 more
core   +3 more sources

An Engineered Living Material With Pro‐Angiogenic Activity Inducible by Near‐Infrared Light

Advanced Functional Materials, EarlyView.
NIR‐responsive engineered living materials (ELMs) for controlled angiogenesis: Near‐infrared (800 nm) light activates engineered probiotic bacteria within alginate‐based living materials to secrete a blood vessel‐regenerating protein. The released protein promotes pro‐angiogenic effects in endothelial networks and chick chorioallantoic membranes.
Anwesha Chatterjee, Stefanie S. M. Meier, Sara Trujillo, Andreas Möglich, Shrikrishnan Sankaran   +4 more
wiley   +1 more source

Pregnane X receptor activation promotes hematopoiesis during liver regeneration by inducing proliferation of hematopoietic stem and progenitor cells in mice

Pharmacological Research
Liver regeneration is a complex process that involves the recruitment of bone marrow (BM)-derived hematopoietic stem and progenitor cells (HSPCs).
Shuang Hu, Chenghua Wu, Dan Li, Xiaowen Jiang, Peng Wang, Guofang Bi, Hui Ouyang, Fengting Liang, Wenhong Zhou, Xiao Yang, Jian-Hong Fang, Huichang Bi   +11 more
doaj   +1 more source