Results 131 to 140 of about 1,150,856 (250)

Living Donor Re-transplantation for Repeated Acute Liver Failure

International Journal of Organ Transplantation Medicine, 2018
Emergency liver transplantation (LT) for acute liver failure (ALF) is a life-saving treatment. Occurrence of this situation in the same patient twice is very rare.
V Ince, C Kayaalp, E Otan, F Ozdemir, A Dirican, HI Toprak, C Aydin, C Ara, S Yilmaz   +8 more
doaj  

Compensatory Mitophagy via NEDD4/HIF‐1α/BNIP3 Pathway Restrains EndMT and Renal Allograft Interstitial Fibrosis Induced by TNFα

Advanced Science, EarlyView.
The role of TNFα in the process of renal allograft interstitial fibrosis is complex and multifaceted. As it can promote renal allograft interstitial fibrosis by inducing mitochondrial dysfunction and EndMT, and also mediating compensatory mitophagy through the NEDD4–HIF‐1α–BNIP3 pathway, which clears damaged mitochondria and inhibits EndMT, thereby ...
Dengyuan Feng, Qinghuan Shen, Junqi Zhang, Jiawen Liu, Zeping Gui, Zijie Wang, Qianguang Han, Shuang Fei, Hao Chen, Li Sun, Jun Tao, Zhijian Han, Xiaobing Ju, Min Gu, Jianjian Zhang, Ruoyun Tan   +15 more
wiley   +1 more source

The International Liver Transplantation Society living donor liver transplant recipient guideline

, 2017
Living donor liver transplantation (LDLT) has been increasingly embraced around the world as an important strategy to address the shortage of deceased donor livers.
Lo, CM, Quintini, Cristiano, Lee, SG, Durand, F, Kyrana, E, Lerut, J, Kyrana, Eirini, Lee, Sung-Gyu, Kim-Schluger, HL, Quintini, C, Kim-Schluger, Hyung Leona, Pomfret, Elizabeth Anne, Heimbach, Julie K, Lerut, Jan, Miller, Charles M, Dhawan, A, Dhawan, Anil, Durand, Francois, Lo, Chung-Mau, Miller, CM, Heimbach, JK, Pomfret, EA   +21 more
core   +1 more source

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

Advanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang, Jianhua Li, Huilu Zhang, Qi Qin, Yichen Huang, Xiaofan Tian, Chao Sun, Binbin Li, Zhengxin Wang, Xin Zhang   +9 more
wiley   +1 more source

Donor safety in living donor liver transplantation: The Korean organ transplantation registry study.

, 2017
Major concerns about donor safety cause controversy and limit the use of living donor liver transplantation to overcome organ shortages. The Korean Organ Transplantation Registry established a nationwide organ transplantation registration system in 2014.
이재근, 김명수
core   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

PROGNOSTIC VALUE OF THE ABSENCE OF ACTIVE RESIDUAL HCC IN NATIVE LIVER SUCH AS PREDICTOR OF TUMOR RECURRENCE AFTER LIVER TRANSPLANTATION

, 2010
INTRODUCTION Negative prognostic factors for HCC recurrence after liver transplant (LT) are still matter of debate. The absence of active residual tumor in the native liver, due to high effectiveness of pre-LT loco-regional treatments or liver resection,
Iemmolo RM, Marino M, Losi L, Guerrini GP, Smerieri N, Tarantino G, De Pietri L, Di Benedetto F, Rompianesi G, Gerunda GE, Cautero N, Ballarin R, Montalti R, Serra V   +13 more
core  

Acute phase circulating micoRNAs predict tumor recurrence and survivals of hepatocellular carcinoma patients after liver transplantation

, 2012
BACKGROUND AND AIM: Tumor recurrence remains a critical issue in liver transplantation for hepatocelluar carcinoma (HCC) patients especially using living donor graft. However, there is a lack of effective prognostic biomarker.
Lo, CM, Man, K, Chan, SC, Li, CX, Wong, N, Ng, KTP   +5 more
core   +1 more source

A Soft, Flexible Implant for Wireless Photothermal–Pyroelectric Neurostimulation

Advanced Science, EarlyView.
A replication strategy is used to enlarge the exposed surface area of barium titanate within flexible films with embedded carbon nanotubes, enabling efficient photothermal‐pyroelectric stimulation. Polar crystalline nanosheets show superior performance in guiding neural progenitor cells toward neuronal differentiation.
Jiang Wu, Minmin Mao, Beltzane Garcia Cirera, Hao Ye, Xiangzhong Chen, Josep Puigmartí‐Luis, Ni Qin, Salvador Pané   +7 more
wiley   +1 more source

Tumor-Associated Macrophages in Hepatocellular Carcinoma: From Ontogeny and Heterogeneity to Immune Evasion and Therapeutic Targeting

Journal of Hepatocellular Carcinoma
Yuhao Su, Yuxin Liang, Deyuan Zhong, Yahui Chen, Shuo Shuo Ma, Xiaolun Huang Department of Liver Transplantation Center and HBP Surgery, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science ...
Su Y, Liang Y, Zhong D, Chen Y, Ma SS, Huang X   +5 more
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