Results 171 to 180 of about 501,737 (303)

Achievements, Challenges and Promises of Minimally Invasive Liver Transplantation. [PDF]

Transpl Int
Gomez C, Labgaa I, Karam E, Dondero F, Beghdadi N, Hobeika C, Dokmak S, Lesurtel M.   +7 more
europepmc   +1 more source

Causal Prediction of TP53 Variant Pathogenicity Using a Perturbation‐Informed Protein Language Model

Advanced Science, EarlyView.
A TP53‐specific predictor, CaVepP53, is developed by fine‐tuning ESMC on experimentally validated variants, quantifying pathogenicity via Euclidean distances. It outperforms general‐purpose models and extends to five cancer genes, enabling interpretable variant classification for precision medicine.
Huiying Chen, Yang Zhao, Boqiang Hu, Wuke Wang, Minfang Song, Annabeth Xinyu Zhao, Xiangyang Li, Gefei Wang, Yanfen Wang, Weiyan Zheng, Xinpeng Zhang, Xia Lin, Yanbin Yin, Xingxu Huang, Jinfang Zheng, Tingbo Liang   +15 more
wiley   +1 more source

The role of EUS in liver transplantation. [PDF]

Hepatol Forum
Cindoruk C, Bardak AE, Yildiz E, Gurakar M, Donmez AE, Elsawy M, Ozturk NB, Toruner MD, Simsek C, Cindoruk M, Gurakar A.   +10 more
europepmc   +1 more source

Alternating High‐Fat and Polysaccharide Diets Modulates Gut Phage‐Bacterial Interplay

Advanced Science, EarlyView.
This study reveals how alternating high‐fat and polysaccharide diets reshape the human gut virome and enhance phage‐bacteria interactions. Using large‐scale metagenomic meta‐analysis and a time‐resolved mouse model, the authors show that diets strongly modulate phage abundance, lifestyle, and gene exchange, offering new insights into nutrition‐guided ...
Fengxiang Zhao, Ruiqi Zhang, Rujun Wei, Huimin Fan, Yongfei Hu, Wenyu Shi, Jinfeng Wang   +6 more
wiley   +1 more source

Barriers to liver transplantation in the Arab world. [PDF]

World J Transplant
Hawwa S, Morad AK, Rifi R, El Masri D, Obeid K, Baroud T, Afyouni A, Tlayss M, Al Chaar S, Masri JE, Salameh P.   +10 more
europepmc   +1 more source

Clinical liver transplantation [PDF]

, 1969
Brettschneider, L, Giles, G, Penn, I, Picache, R, Putnam, CW, Starzl, TE   +5 more
core   +1 more source

Maternal Preconception Antibiotic Exposure Disrupts Microbial Succession: A Transgenerational Risk for Offspring Gut Mucosal Immaturity and Colitis Susceptibility

Advanced Science, EarlyView.
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen, Ruqiao Duan, Cunzheng Zhang, Gaonan Li, XiaoLin Ji, Qi Zhang, Fei Pei, Kun Wang, Liping Duan   +8 more
wiley   +1 more source

Application of the novel peroral choledochoscope in hepatolithiasis after liver transplantation. [PDF]

Endoscopy
Lin X, Cheng W, Qiu X, Sun J, Chen S, Peng H, Dai Z.   +6 more
europepmc   +1 more source

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source

Cirrhotic cardiomyopathy: pathophysiology, assessment, and implications for liver transplantation. [PDF]

Ther Adv Gastroenterol
Gill M, Koshy AN, Ramachandran J, McCaughan GW, Majumdar A.   +4 more
europepmc   +1 more source