Results 11 to 20 of about 3,082,572 (406)

Hypothermic Machine Perfusion in Liver Transplantation - A Randomized Trial.

New England Journal of Medicine, 2021
BACKGROUND Transplantation of livers obtained from donors after circulatory death is associated with an increased risk of nonanastomotic biliary strictures.
R. van Rijn, Ivo J. Schurink, Y. de Vries, A. P. van den Berg, M. Cortés Cerisuelo, S. Darwish Murad, J. Erdmann, N. Gilbo, R. D. de Haas, N. Heaton, B. van Hoek, V. Huurman, I. Jochmans, O. B. van Leeuwen, V. D. de Meijer, D. Monbaliu, W. Polak, J. Slangen, R. Troisi, A. Vanlander, J. de Jonge, R. Porte   +21 more
semanticscholar   +1 more source

Cholangiocyte organoids can repair bile ducts after transplantation in the human liver

Science, 2021
Organoids regenerate human bile ducts Bile ducts carry bile from the liver and gall bladder to the small intestine, where it aids digestion. Cholangiocytes are epithelial cells that line bile ducts and modify bile as its transported through the biliary ...
F. Sampaziotis, D. Muraro, Olivia C. Tysoe, S. Sawiak, T. Beach, E. Godfrey, S. Upponi, T. Brevini, B. Wesley, J. Garcia-Bernardo, Krishnaa T. Mahbubani, Giovanni Canu, Richard L. Gieseck, N. L. Berntsen, Victoria L. Mulcahy, K. Crick, C. Fear, Sharayne Robinson, L. Swift, L. Gambardella, Johannes Bargehr, Daniel Ortmann, S. Brown, Anna Osnato, M. Murphy, G. Corbett, W. Gelson, G. Mells, Peter Humphreys, S. Davies, I. Amin, P. Gibbs, S. Sinha, S. Teichmann, A. Butler, T. See, E. Melum, C. Watson, K. Saeb‐Parsy, L. Vallier   +39 more
semanticscholar   +1 more source

Postliver Transplantation Rhino-Orbital Mucormycosis, an Unexpected Cause of a Downhill Course

Case Reports in Hepatology, 2022
The COVID-19 pandemic has impacted transplantation worldwide in a major way with infections and post-COVID-19 complications contributing to increased mortality and morbidity.
Swapnali Sabhapandit, Mithun Sharma, Anuradha Sekaran, Balachandran Menon, Anand Kulkarni, Soumya TR, Padaki Nagaraja Rao, Duvurr Nageshwar Reddy   +7 more
doaj   +1 more source

Integrative analyses identify CD73 as a prognostic biomarker and immunotherapeutic target in intrahepatic cholangiocarcinoma

World Journal of Surgical Oncology, 2023
Background CD73 promotes progression in several malignancies and is considered as a novel immune checkpoint. However, the function of CD73 in intrahepatic cholangiocarcinoma (ICC) remains uncertain.
Bao-Ye Sun, Zhang-Fu Yang, Zhu-Tao Wang, Gao Liu, Cheng Zhou, Jian Zhou, Jia Fan, Wei Gan, Yong Yi, Shuang-Jian Qiu   +9 more
doaj   +1 more source

SQSTM1/p62 in intrahepatic cholangiocarcinoma promotes tumor progression via epithelial–mesenchymal transition and mitochondrial function maintenance

Cancer Medicine, 2023
Background SQSTM1/p62 is a selective autophagy receptor that regulates multiple signaling pathways participating in the initiation and progression of tumors.
Jiafeng Chen, Zheng Gao, Xiaogang Li, Yinghong Shi, Zheng Tang, Weiren Liu, Xin Zhang, Ao Huang, Xuanming Luo, Qiang Gao, Guangyu Ding, Kang Song, Jian Zhou, Jia Fan, Xiutao Fu, Zhenbin Ding   +15 more
doaj   +1 more source

Diminishing Use of Liver Biopsy among Liver Transplant Recipients for Hepatitis C. [PDF]

, 2017
Background and Aims: Hepatitis C virus (HCV) cirrhosis is the leading indication for liver transplantation in the United States and recurrent HCV following liver transplantation is a major cause of allograft loss and mortality.
Aby, Elizabeth, Agopian, Vatche, Busuttil, Ronald W, French, Samuel W, Grotts, Jonathan F, Jimenez, Melissa A, Saab, Sammy   +6 more
core   +1 more source

Liver Transplantation [PDF]

Seminars in Liver Disease, 1999
Since the first human liver transplant done in 1963, the procedure has become a routine procedure with an excellent outcome in terms both of quality and of length of survival. The development and introduction into clinical practice of a variety of immunosuppressive agents has given the clinician a bewildering array of therapeutic options but with a ...
openaire   +4 more sources

The impact of thrombocytopenia on prognosis of HBV-related small hepatocellular carcinoma: a propensity score matching analysis

World Journal of Surgical Oncology, 2021
Background Thrombocytopenia was reported both detrimental and advantageous to hepatocellular carcinoma (HCC). However, there is little evidence showing clearly the clinical value of preoperative thrombocytopenia on the surgical outcome of patients with ...
Wei Peng, Chuan Li, Xiaoyun Zhang, Tianfu Wen, Zheyu Chen   +4 more
doaj   +1 more source

Indwelling Pleural Catheters in Hepatic Hydrothorax: A Single-Center Series of Outcomes and Complications [PDF]

, 2018
Background Treatment of hepatic hydrothorax (HH) generally involves sodium restriction, diuretics, and serial thoracentesis. In more advanced cases, transjugular intrahepatic portosystemic shunt and liver transplantation may be required.
Bosslet, Gabriel, Diab, Khalil, Ghabril, Marwan, Kniese, Christopher   +3 more
core   +1 more source

Nonalcoholic steatohepatitis is the second leading etiology of liver disease among adults awaiting liver transplantation in the United States.

Gastroenterology, 2015
BACKGROUND & AIMS Nonalcoholic steatohepatitis (NASH) has been predicted to become the leading indication for liver transplantation (LT) in the United States.
R. Wong, M. Aguilar, R. Cheung, R. Perumpail, S. Harrison, Z. Younossi, Aijaz Ahmed   +6 more
semanticscholar   +1 more source