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This assessment of the role of liver transplantation in treating end-stage liver disease today is based on two major series, one from Denver and the other from the Cambridge/Kings College Hospital, England. The findings of these groups are highlighted, as are the changes in technique that have led to considerably improved survival in the past two years.
Terblanche, J, Koep, LJ, Starzl, TE
core +7 more sources
The development of liver transplantation has been difficult. However, substantial advances have been made mostly because of better surgical techniques and because of better postoperative management. It has been necessary for surgeons to be more inquisitive about the reasons for post-transplantation liver dysfunction rather than to ascribe hepatic ...
G W, McCaughan, D J, Koorey
+10 more sources
Advances in the management of both chronic and acute hepatic disease have been made possible and even mandated by the development of liver transplantation. The clinical use of transplantation has proceeded at a rapid pace since a Consensus Development Conference of the National Institutes of Health concluded in June 1983 that liver transplantation had ...
D. H. Van Thiel+2 more
+11 more sources
Hypothermic Machine Perfusion in Liver Transplantation - A Randomized Trial.
BACKGROUND Transplantation of livers obtained from donors after circulatory death is associated with an increased risk of nonanastomotic biliary strictures.
R. van Rijn+21 more
semanticscholar +1 more source
Continued discussion over organ allocation and distribution remained a focal point in the field of liver transplantation in the year 2000. Despite the ongoing debate, no significant changes were implemented in the current allocation system. By far, the most widely discussed topic in liver transplantation this year was live donor adult-to-adult liver ...
Brown, KA, Moonka, DK
openaire +6 more sources
Transplantation of the Liver [PDF]
The authors’ results with liver transplantation are presented, along with their present views regarding candidacy for liver replacement and selected diagnostic and technical problems that are encountered during and after liver transplantation, particularly the problem of secondary jaundice.
Putnam, CW, Starzl, TE
openaire +3 more sources
Cholangiocyte organoids can repair bile ducts after transplantation in the human liver
Organoids regenerate human bile ducts Bile ducts carry bile from the liver and gall bladder to the small intestine, where it aids digestion. Cholangiocytes are epithelial cells that line bile ducts and modify bile as its transported through the biliary ...
F. Sampaziotis+39 more
semanticscholar +1 more source
Liver transplantation has become a lifesaving procedure for patients who have chronic end-stage liver disease and acute liver failure. The satisfactory outcome of liver transplantation has led to insufficient supplies of deceased donor organs, particularly in East Asia.
Moon, Deok-Bog, Lee, Sung-Gyu
openaire +3 more sources
Increased morbidity associated with secondary abdominal closure in pediatric liver transplantation. [PDF]
Background The discrepancy in size between donor and recipient presents a complex challenge in pediatric liver transplantation (PLT), often necessitating secondary abdominal closure to prevent abdominal compartment syndrome.
Costa CM+9 more
europepmc +2 more sources
Background The prognosis of patients with combined hepatocellular carcinoma and intrahepatic cholangiocarcinoma (CHC) is usually poor, and effective adjuvant therapy is missing making it important to investigate whether these patients may benefit from ...
Wei-Ren Liu+14 more
doaj +1 more source