Results 41 to 50 of about 759,882 (252)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Accuracy of estimated total liver volume formulas before liver resection

, 2019
Background: Future remnant liver volume is used to predict the risk for liver failure in patients who will undergo major liver resection. Formulas to estimate total liver volume based on biometric data are widely used to calculate future remnant liver ...
Olthof, Pim B., de Santibañes, Eduardo, Oldhafer, Karl, Malago, Massimo, van Dam, Ronald, van Dam, Ronald M., Schadde, Erik, Abdalla, Eddie K., Campos, Ricardo Robles, Jovine, Elio   +9 more
core   +1 more source

Automated quantitative assessment of pediatric blunt hepatic trauma by deep learning-based CT volumetry

European Journal of Medical Research, 2022
Background To develop an end-to-end deep learning method for automated quantitative assessment of pediatric blunt hepatic trauma based on contrast-enhanced computed tomography (CT).
Shungen Huang, Zhiyong Zhou, Xusheng Qian, Dashuang Li, Wanliang Guo, Yakang Dai   +5 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Deportalization, Venous Congestion, Venous Deprivation: Serial Measurements of Volumes and Functions on Morphofunctional 99mTc-Mebrofenin SPECT-CT

Diagnostics, 2020
The objective was to assess the changes in regional volumes and functions under venous-impaired vascular conditions following liver preparation. Twelve patients underwent right portal vein embolization (PVE) (n = 5) or extended liver venous deprivation ...
Lauranne Piron, Emmanuel Deshayes, Christophe Cassinotto, François Quenet, Fabrizio Panaro, Margaux Hermida, Carole Allimant, Eric Assenat, Georges-Philippe Pageaux, Nicolas Molinari, Boris Guiu   +10 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Stereology: a novel technique for rapid assessment of liver volume

Insights into Imaging, 2012
Background The purpose of this study was to test the stereology method using several grid sizes for measuring liver volume and to find which grid provides an accurate estimate of liver volume.
Michael R. Torkzad, Agneta Norén, Joel Kullberg   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Survival after liver transplantation in the United Kingdom and Ireland compared with the United States

, 2007
<b>Background and Aim</b>: Surgical mortality in the US is widely perceived to be superior to that in the UK. However, previous comparisons of surgical outcome in the two countries have often failed to take sufficient account of case-mix or ...
van der Meulen, JHP, Copley, LP, van der Meulen, J., Gimson, AE, Lewsey, J.D., Dawwas, M.F., Gimson, A.E., Lewsey, JD, Copley, L.P., Dawwas, MF   +9 more
core   +1 more source

Body surface area and body weight predict total liver volume in Western adults [PDF]

, 2002
Computed tomography (CT) is used increasingly to measure liver volume in patients undergoing evaluation for transplantation or resection. This study is designed to determine a formula predicting total liver volume (TLV) based on body surface area (BSA ...
Ferrari, G, Loyer, EM, Abdalla, Eddie K., Vauthey, Jean-Nicolas, Mathey, C, Loyer, E.M., Fenstermacher, MJ, Do, KA, Lerut, Jan, Wang, X., Herron, D., Gertsch, Philippe, Materne, R, Denys, A., Denys, A, Loyer, Evelyne M., Mathey, Christian, Abdalla, E.K., Materne, R., Encarnacion, Arthur, Wang, Xuemei, Denys, Alban, Charnsangavej, C, Herron, D, Fenstermacher, Marc J., Encarnacion, A., Encarnacion, A, Herron, Delise, Do, Kim-Anh, Leurt, Jan, Abdalla, Eddie, Doherty, DA, Do, K.A., Ferrari, Giovanni, Charnsangavej, Chusilp, Charnsangavej, C., Doherty, Dorota A., Ferrari, G., Mathey, C., Doherty, D.A., Gertsch, P., Materne, Roland, Fenstermacher, M.J., Wang, XM, Vauthey, J.N., Vauthey, JN, Lerut, J.   +46 more
core   +1 more source