Results 61 to 70 of about 9,593,679 (252)

The Impact of Unilateral 90Y-radioembolization on Functional Changes in the Contralateral Hepatic Lobe

Annals of Surgery Open, 2021
Objectives:. To investigate how metabolic function of the contralateral liver lobe is affected by unilateral radioembolization (RE), and to compare the changes in volume and metabolic function. Background:.
Benjamin Garlipp, MD, Holger Amthauer, MD, Dennis Kupitz, DMP, Oliver S. Grosser, DMP, Julian Jürgens, MD, Robert Damm, MD, Maciej Powerski, MD, Matthias Fabritius, MD, Osman Oecal, MD, Patrick Stuebs, MD, Christoph Benckert, MD, Ricarda Seidensticker, MD, Jens Ricke, MD, Maciej Pech, MD, Max Seidensticker, MD   +14 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Sarcopenia negatively affects preoperative total functional liver volume in patients undergoing liver resection.

, 2013
Objectives: Sarcopenia may negatively affect short-term outcomes after liver resection. The present study aimed to explore whether total functional liver volume (TFLV) is related to sarcopenia in patients undergoing partial liver resection.
Reisinger, K.W., von Meyenfeldt, M.F., van den Broek, M.A., Lodewick, T.M., van Dam, R.M., Olde Damink, S., Dello, S.A.W.G., Dejong, C.H.C., Bemelmans, M.H.A., Olde Damink, S.; id_orcid   +9 more
core   +1 more source

Mobilization of multilineage-differentiating stress-enduring cells into the peripheral blood in liver surgery.

PLoS ONE, 2022
PurposeThis study investigated whether liver damage severity relates to the mobilization of multilineage-differentiating stress-enduring (Muse) cells, which are endogenous reparative pluripotent stem cells, into the peripheral blood (PB) and whether the ...
Koji Kikuchi, Hirokatsu Katagiri, Yuji Suzuki, Hiroyuki Nitta, Akira Sasaki   +4 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Effects of the liver volume and donor steatosis on errors in the estimated standard liver volume

, 2011
An accurate assessment of donor and recipient liver volumes is essential in living donor liver transplantation. Many liver donors are affected by mild to moderate steatosis, and steatotic livers are known to have larger volumes.
Lo, CM, Chok, KSH, Fan, ST, Rohan Chaminda Siriwardana, Sheung Tat Fan, Chung Mau Lo, Chan, SC, See Ching Chan, Kenneth Siu Ho Chok, Siriwardana, RC   +9 more
core   +1 more source

Body surface area and body weight predict total liver volume in Western adults [PDF]

, 2002
Computed tomography (CT) is used increasingly to measure liver volume in patients undergoing evaluation for transplantation or resection. This study is designed to determine a formula predicting total liver volume (TLV) based on body surface area (BSA ...
Ferrari, G, Loyer, EM, Abdalla, Eddie K., Vauthey, Jean-Nicolas, Mathey, C, Loyer, E.M., Fenstermacher, MJ, Do, KA, Lerut, Jan, Wang, X., Herron, D., Gertsch, Philippe, Materne, R, Denys, A., Denys, A, Loyer, Evelyne M., Mathey, Christian, Abdalla, E.K., Materne, R., Encarnacion, Arthur, Wang, Xuemei, Denys, Alban, Charnsangavej, C, Herron, D, Fenstermacher, Marc J., Encarnacion, A., Encarnacion, A, Herron, Delise, Do, Kim-Anh, Leurt, Jan, Abdalla, Eddie, Doherty, DA, Do, K.A., Ferrari, Giovanni, Charnsangavej, Chusilp, Charnsangavej, C., Doherty, Dorota A., Ferrari, G., Mathey, C., Doherty, D.A., Gertsch, P., Materne, Roland, Fenstermacher, M.J., Wang, XM, Vauthey, J.N., Vauthey, JN, Lerut, J.   +46 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Living donor liver transplantation for acute liver failure in pediatric patients caused by the ingestion of fireworks containing yellow phosphorus

, 2011
Yellow phosphorus is a protoplasmic toxicant that targets the liver. The ingestion of fireworks containing yellow phosphorus, either by children who accidentally consume them or by adults who are attempting suicide, often results in death due to acute ...
Işık, Burak, Selimoğlu, Mukadder Ayşe, Kayaalp, Cüneyt, Yılmaz, Sezai, Aydın, Cemalettin, Ara, Cengiz, Ateş, Mustafa, Yılmaz, Mehmet, Özgör, Dinçer, Dirican, Abuzer   +9 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source