Results 61 to 70 of about 759,882 (252)

A Validation Study of Liver Volumetry Estimation by a Semiautomated Software in Patients Undergoing Hepatic Resections

Journal of Clinical Interventional Radiology ISVIR, 2020
Purpose The purpose of this study was to validate the use of a semiautomated software for liver volumetry preoperatively by comparing it with the volume of resected specimen in patients undergoing hepatic resections.
Suyash S. Kulkarni, Nitin Sudhakar Shetty, Kunal B. Gala, Shraddha Patkar, Amrita Narang, Ashwin M. Polnaya, Sushil Patil, Neeraj G. Shetty, Falguni Hota, Mahesh Goel   +9 more
doaj   +1 more source

The Impact of Unilateral 90Y-radioembolization on Functional Changes in the Contralateral Hepatic Lobe

Annals of Surgery Open, 2021
Objectives:. To investigate how metabolic function of the contralateral liver lobe is affected by unilateral radioembolization (RE), and to compare the changes in volume and metabolic function. Background:.
Benjamin Garlipp, MD, Holger Amthauer, MD, Dennis Kupitz, DMP, Oliver S. Grosser, DMP, Julian Jürgens, MD, Robert Damm, MD, Maciej Powerski, MD, Matthias Fabritius, MD, Osman Oecal, MD, Patrick Stuebs, MD, Christoph Benckert, MD, Ricarda Seidensticker, MD, Jens Ricke, MD, Maciej Pech, MD, Max Seidensticker, MD   +14 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Sarcopenia negatively affects preoperative total functional liver volume in patients undergoing liver resection.

, 2013
Objectives: Sarcopenia may negatively affect short-term outcomes after liver resection. The present study aimed to explore whether total functional liver volume (TFLV) is related to sarcopenia in patients undergoing partial liver resection.
Reisinger, K.W., von Meyenfeldt, M.F., van den Broek, M.A., Lodewick, T.M., van Dam, R.M., Olde Damink, S., Dello, S.A.W.G., Dejong, C.H.C., Bemelmans, M.H.A., Olde Damink, S.; id_orcid   +9 more
core   +1 more source

The utility of liver function tests for mortality prediction within one year in primary care using the algorithm for liver function investigations (ALFI) [PDF]

, 2012
BACKGROUND: Although liver function tests (LFTs) are routinely measured in primary care, raised levels in patients with no obvious liver disease may trigger a range of subsequent expensive and unnecessary management plans.
Roderick Paul, Donnan, Peter T, John F. Dillon (110507), Stephen D Ryder, McLernon, DJ, Rosenberg, WM, McLernon, D.J., McLernon David J., Roderick, P., William M. Rosenberg (110512), Roderick, Paul, Donnan, PT, Dillon, John F.; id_orcid, McLernon, David J., David J McLernon, Rosenberg, William M, Paul Roderick, Donnan, Peter T.; id_orcid, Sullivan, F.M., Dillon, J.F., Ryder, Stephen D., Sullivan, Frank M, Ryder, S.D., McLernon, David J, Rosenberg, William M., Dillon, John F., John F Dillon, Peter T. Donnan (110517), Donnan, Peter T., Roderick, P, Paul Roderick (14856), Donnan, P.T., Sullivan, FM, Ryder Stephen D., Sullivan Frank M., David J. McLernon (110505), Donnan Peter T., Peter T Donnan, Dillon, John F, Rosenberg, W.M., Frank M Sullivan, Rosenberg William M., Ryder, SD, Dillon, JF, Frank M. Sullivan (110508), William M Rosenberg, Sullivan, Frank M., Ryder, Stephen D, Dillon John F., Stephen D. Ryder (110515)   +49 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Sarcopenia, obesity and sarcopenic obesity : effects on liver function and volume in patients scheduled for major liver resection

, 2015
BACKGROUND: Sarcopenia, obesity and sarcopenic obesity have been linked to impaired outcome after liver surgery. Preoperative liver function of sarcopenic, obese and sarcopenic-obese patients might be reduced, possibly leading to more post-operative ...
Lodewick, Toine M., Gaßler, Nikolaus, Dello, S.A., Alizai, Patrick H., Schneider, M., Dello, Simon A. W. G., Alizai, P.H., Neumann, Ulf Peter, Olde Damink, Steven W. M., van Dam, Ronald M., Neumann, U. P., Dejong, Cornelis H. C., Dejong, C.H., Röth, Anjali Anna Joy, Alizai, Patrick Hamid, Lodewick, T.M., van Dam, R.M., Gassler, N., Damink, S.W.; id_orcid, Schmeding, Maximilian, Neumann, Ulf P., Roeth, A.A., Damink, S.W., Schmeding, M., Schneider, Mark   +24 more
core   +1 more source

Clinical Investigation of Remnant Liver Volume-to-Body Weight Ratio in Predicting Post-hepatectomy Liver Failure in Patients with Hepatocellular Carcinoma in Cirrhotic Liver

Zhongliu Fangzhi Yanjiu, 2018
Objective To explore a new cut-off of remnant liver volume-to-body weight ratio (RLV-BWR) and investigate the relationship between RLV-BWR and post-hepatectomy liver failure (PHLF) in patients with hepatocellular carcinoma (HCC) of cirrhotic liver ...
LU Zhan, GONG Wenfeng, ZHANG Zhiyuan, ZHONG Jianhong, MA Liang, XIANG Bangde, LI Lequn   +6 more
doaj   +1 more source