Results 171 to 180 of about 792,189 (305)

Obesity Subtypes and Longitudinal Trajectories of Function Over Seven Years of Follow‐Up: Data From the Multicenter Osteoarthritis Study

Arthritis Care &Research, EarlyView.
Objective Obesity, defined by body mass index (BMI) ≥30 kg/m2, is a risk factor for functional limitations in people with knee osteoarthritis (OA). However, function varies among such individuals. Our objective was to evaluate the implications of obesity subtypes on longitudinal patterns of physical functioning in people with or at risk for knee OA ...
Kristine Godziuk, Sarah Tilley, Michael LaValley, Michael C. Nevitt, Cora E. Lewis, James C. Torner, Tuhina Neogi, for the Multicenter Osteoarthritis Study Group   +7 more
wiley   +1 more source

Liver X receptor: A potential target for inflammatory bowel disease and colorectal cancer (Review). [PDF]

Mol Med Rep
Li Y, Fu X, Bai M, Zhou J, Qiu J, Zhang H, Liang S, Liu M.   +7 more
europepmc   +1 more source

Liver X Receptor Activation Attenuates Oxysterol-Induced Inflammatory Responses in Fetoplacental Endothelial Cells. [PDF]

Cells, 2023
George M, Lang M, Gali CC, Babalola JA, Tam-Amersdorfer C, Stracke A, Strobl H, Zimmermann R, Panzenboeck U, Wadsack C.   +9 more
europepmc   +1 more source

Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults With Inflammatory Bowel Disease: Data From a Large Administrative Claims Cohort

Arthritis Care &Research, EarlyView.
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer, Rui Xiao, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +4 more
wiley   +1 more source

A Computational Framework to Evaluate Interactions of BPA and Its Analogs with Human Liver X Receptor-Beta for Health Risk Assessment. [PDF]

Chem Res Toxicol
Pathak RK, Kumar S, Kumar V.
europepmc   +1 more source

Targeting macrophages in atherosclerosis using nanocarriers loaded with liver X receptor agonists: A narrow review. [PDF]

Front Mol Biosci, 2023
Yang TM, Miao M, Yu WQ, Wang X, Xia FJ, Li YJ, Guo SD.   +6 more
europepmc   +1 more source

Neighborhood Socioeconomic Status and Short‐Term Functional Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective Individuals with systemic lupus erythematosus (SLE) can accumulate functional status (FS) impairment. We evaluated the association between neighborhood socioeconomic disadvantage, as measured by the Area Deprivation Index (ADI), and FS in a national SLE sample.
Baljeet Rai, Jessica Fitzpatrick, Jing Li, Eric Roberts, Patricia Katz, Laura Plantinga, Gabriela Schmajuk, Jinoos Yazdany   +7 more
wiley   +1 more source

Expression of the inhibitory receptor NKG2A correlates with increased liver and splenic NK cell response to activating receptor engagement [PDF]

, 2017
Key, Phillip N, Meyer, Claire E, Ni, Ann, Shabsovich, Mark, Tripathy, Sandeep K, Zhu, Toby   +5 more
core   +2 more sources

Liver X Receptor Beta Regulates Glial Dynamics and Cortical Network Remodeling in a Freezing Lesion-Cortical Dysplasia Model. [PDF]

CNS Neurosci Ther
Zhang Z, Du D, Song M, Li J, Dong X, Mei Y, Zhang J, Zhang M, Ma Y, Yu S, Shu H, Chen X.   +11 more
europepmc   +1 more source

Enhanced liver X receptor signalling reduces brain injury and promotes tissue regeneration following experimental intracerebral haemorrhage: roles of microglia/macrophages. [PDF]

Stroke Vasc Neurol, 2023
Zhang R, Dong Y, Liu Y, Moezzi D, Ghorbani S, Mirzaei R, Lozinski BM, Dunn JF, Yong VW, Xue M.   +9 more
europepmc   +1 more source