Arthritis Care &Research, Accepted Article.Objective The objective of this article is to identify perceptions of SLE patients regarding artificial intelligence (AI)‐based online symptom assessment tools, and the potential of these tools to address diagnostic barriers. Methods Adults from our SLE research cohort were invited to participate in 60‐90 minute virtual focus groups concerning their ...
Olivia A. Stein +7 more
wiley +1 more source
Scaffold Fusion and SAR Transfer with a Chemical Language Model Generates Novel Liver X Receptor Modulators. [PDF]
J Med ChemBandomir NC +5 more
europepmc +1 more source
Liver X Receptor-Inducible Host E3 Ligase IDOL Targets a Human Cytomegalovirus Reactivation Determinant. [PDF]
J Virol, 2023 Mlera L +9 more
europepmc +1 more source
Arthritis Care &Research, Accepted Article.Objectives Race and household income impact outcomes in patients with rheumatic conditions; however, their role in pediatric anti‐neutrophil cytoplasmic antibody (ANCA)‐associated vasculitis (AAV) remains poorly understood. We aimed to evaluate whether race/ethnicity and household income are associated with severe AAV disease and renal outcomes among ...
Roberto Alejandro Valdovinos +2 more
wiley +1 more source
Liver X Receptor Activation Alleviates Hepatic Ischemia-Reperfusion Injury in Diabetes by Inhibiting NF-κB-NLRP3 Activation. [PDF]
Immun Inflamm DisJiang C, Ding W, Hu Y, Yang C.
europepmc +1 more source
The mechanism of liver X receptor regulates the balance of glycoFAsynthesis and cholesterol synthesis in clear cell renal cell carcinoma. [PDF]
Clin Transl Med, 2023 Wang Q +8 more
europepmc +1 more source
Harnessing Fungal Biowelding for Constructing Mycelium‐Engineered Materials
Advanced Engineering Materials, EarlyView.Mycelium‐bound composites (MBCs) offer low‐carbon alternatives for construction, yet interfacial bonding remains a critical challenge. This review examines fungal biowelding as a biocompatible adhesive, elucidating mycelium‐mediated interfacial mechanisms and their role in material assembly. Strategies to optimize biowelding are discussed, highlighting
Xue Brenda Bai +2 more
wiley +1 more source
Claudin-4-adhesion signaling drives breast cancer metabolism and progression via liver X receptor β. [PDF]
Breast Cancer Res, 2023 Murakami-Nishimagi Y +9 more
europepmc +1 more source
A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions
Advanced Engineering Materials, EarlyView.This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice +2 more
wiley +1 more source
Liver X Receptor and Retinoid X Receptor in Cartilage Development and Homeostasis [PDF]
, 2017 Osteoarthritis (OA) is a heterogeneous and multifactorial degenerative disease characterized by cartilage degradation in the joint. Available treatment options target symptoms but do not address the underlying issue of joint tissue degeneration. A better understanding of the molecular mechanisms maintaining cartilage health is essential for developing ...
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