Identification of integrin drug targets for 17 solid tumor types. [PDF]
Integrins are contributors to remodeling of the extracellular matrix and cell migration. Integrins participate in the assembly of the actin cytoskeleton, regulate growth factor signaling pathways, cell proliferation, and control cell motility.
Arun, Adith S +2 more
core +1 more source
T0901317, an Agonist of Liver X Receptors, Attenuates Neuronal Apoptosis in Early Brain Injury after Subarachnoid Hemorrhage in Rats via Liver X Receptors/Interferon Regulatory Factor/P53 Upregulated Modulator of Apoptosis/Dynamin-1-Like Protein Pathway. [PDF]
Dai J +7 more
europepmc +1 more source
This study explores the impact of environmental pollutants on nuclear receptors (CAR, PXR, PPARα, PPARγ, FXR, and LXR) and their heterodimerization partner, the Retinoid X Receptor (RXR).
Yannick Dauwe +7 more
doaj +1 more source
Liver X receptors and liver diseases
Xiao-Min He, Chang-Bai Liu
openaire +1 more source
Integrating the inputs that shape pancreatic islet hormone release. [PDF]
The pancreatic islet is a complex mini organ composed of a variety of endocrine cells and their support cells, which together tightly control blood glucose homeostasis.
Huising, Mark O, Noguchi, Glyn M
core
Liver X receptors are required for thymic resilience and T cell output. [PDF]
Chan CT +24 more
europepmc +1 more source
The role of atrial natriuretic peptide (ANP) in chronic liver disease. [PDF]
Almeida +82 more
core +1 more source
Exploring the Roles of Liver X Receptors in Lipid Metabolism and Immunity in Atherosclerosis. [PDF]
Endo-Umeda K, Makishima M.
europepmc +1 more source
Liver X Receptors Enhance Epithelial to Mesenchymal Transition in Metastatic Prostate Cancer Cells. [PDF]
Bouchareb E +19 more
europepmc +1 more source

