Results 71 to 80 of about 8,459,231 (297)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Japan Architectural ReviewWe evaluated the effects of walking habits and mobility improvement on an aging population among 30 residents of a suburban residential complex with the aim of promoting sustainable health activities led by residents.
Daisuke Matsushita, Yangcheng Gu
doaj +1 more source
Environment for Healthy Living
, 2023 AbstractHow do we build a healthy vision of the future? What interventions should architects promote to support human health and well-being, and from where do we start? The paper discusses the concept of health in a broader vision through international documents, focusing on the area of action for architects, and stressing the crucial role of ...
openaire +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Older women as occupational beings: exploring the meanings of occupations within the home environment for older women living alone [PDF]
, 2017 There is a discrepancy between the life expectancy of men and women of approximately two and a half years (Taylor Nelson Sofres 2014). This suggests that women are likely to spend a period of time in the latter years of their life living alone.
Wells, G.
core
Assessing the risk of extreme precipitation in Japan through GEV distribution and spatial modeling
Journal of Hydrology: Regional StudiesStudy region: Japan, characterized by diverse climatic zones and complex topography, has experienced increasing frequency and severity of extreme precipitation events in recent decades.
Zhichao Jiao +3 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
The living environments of community-dwelling older people who become frail: another look at the living standards of older New Zealanders survey. [PDF]
, 2006 Efforts to support older people who live in the community and who become frail will be enhanced by a better appreciation of the shared characteristics of this group.
Twitchin, Stephen +3 more
core
KDHE Division of Environment Overview. [2013]
, 2013 application/pdf; "January 17, 2013."; Presentation before the Kansas Legislature, House Committee on Energy & Environment, presented by the Division of Environment, Kansas Department of Health and Environment.Presentation giving a comprehensive overview ...
Kansas. Division of Environment.
core +1 more source
Shading effects on building energy performance: A multi-city analysis
Results in EngineeringThis study presents a simplified methodology to evaluate the effects of surrounding shading elements—such as nearby buildings and trees—on building thermal loads, with a focus on passive cooling.
Xiong Xiao +7 more
doaj +1 more source