Results 71 to 80 of about 913,122 (305)

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

A living lab

open access: yesSpool, 2015
This project is focused on providing movable-temporary sustainable housing at derelict locations in cities, for young people / graduates / singles / expats / professionals in the European market. The goal is to act as the missing link between innovative
Argyrios Papadopoulos
doaj  

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Contextualised Browsing in a Digital Library's Living Lab

open access: yes, 2018
Contextualisation has proven to be effective in tailoring \linebreak search results towards the users' information need. While this is true for a basic query search, the usage of contextual session information during exploratory search especially on the ...
Belkin Nicholas J.   +6 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

El cubo de armonización HSB Living Lab

open access: yesInformes de la Construccion, 2017
Los Living Labs están emergiendo como instrumentos de innovación en actividades centradas en el usuario. Debido al variado rango de enfoques, constelaciones, prácticas, resultados y longevidad, igualmente variadas metodologías se han usado para describir
A. Sasic Kalagasidis, S. Hagy, Ch. Marx
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Living Labs as Tools for Open Innovation [PDF]

open access: yes
This paper presents a Living Lab in Stockholm as a focal point for discussing how the Living Lab concept can be extended and used for engaging in multiorganizational open innovation.
Håkan OZAN   +3 more
core  

Coworking, fab labs et living labs

open access: yesTerritoire en mouvement, 2017
Au sein des pays de l’OCDE, de nombreux dispositifs destines a developper le numerique ont ete mis en place. Profitant de ce developpement technologique, les facons de travailler se diversifient en reponse a la fois au contexte economique (etre performant, efficace et efficient) et aux attentes des employes desireux d’une meilleure conciliation entre ...
Scaillerez, Arnaud   +1 more
openaire   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

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