Results 121 to 130 of about 53,126,315 (234)

LL-37 and citrullinated LL-37: differential modulation of the oxylipin - chemokine axis [PDF]

open access: yes
Inflammation plays a crucial role in the host immune system, and it involves a complex network of cellular and molecular events. In the lungs, human bronchial epithelial cells release cytokines/chemokines, and other mediators such as bioactive lipids and
Ramotar, Padmanie
core  

HA emollient does not reduce LL-37-induced inflammation.

open access: yes, 2013
Experiments were performed as in Figure 7, but with immediate (t = 0) application of 1% w/w HA-containing emollient (53 kDa HA) or 1% w/w GM-1111 emollient ...
Narayanam V. Rao (356295)   +8 more
core   +1 more source

Overcoming the Trade‐Off Between Magnetic Coupling and Electrical Insulation in Soft Magnetic Materials via Nanochain Engineering

open access: yesAdvanced Science, EarlyView.
This study employs a nanochain engineering approach combined with an in situ oxidation strategy to fabricate self‐insulating iron‐based magnetic nanochains, addressing the challenge of balancing magnetic coupling and electrical insulation in soft magnetic materials.
Dingrong Zuo   +8 more
wiley   +1 more source

MOESM5 of Effects of cigarette smoke on barrier function and tight junction proteins in the bronchial epithelium: protective role of cathelicidin LL-37

open access: yes, 2019
Additional file 5: No protective effects of LL-37 on CSE-induced reduction in TEER disappeared at 48 h after CSE exposure. Calu-3 cells pretreated with or without 20 μg/ml LL-37 were exposed to 10% CSE. A.
Miyoko Tatsuta (7843853)   +9 more
core   +1 more source

Gonadotropin‐Inhibitory Hormone (GnIH) and Its Receptor GPR147 Mediates Acute Stress‐Induced Activation of the Locus Coeruleus‐SAM Axis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Gonadotropin‐inhibitory hormone (GnIH, also known as RFamide‐related peptide‐3, RFRP‐3) is a hypothalamic neuropeptide that regulates vertebrate reproduction via its receptor GPR147. Although GnIH is known to mediate stress‐induced reproductive suppression, its role in broader stress responses remains unclear.
Jiani Zhang   +18 more
wiley   +1 more source

An On‐Demand Neuromorphic Vision System Enabled by a Multi‐Paradigm Neuromorphic Device and Hierarchical Reconfigurability Designed from Device to System Level

open access: yesAdvanced Science, EarlyView.
An on‐demand ultra‐reconfigurable intelligent vision system with hierarchical reconfigurability from device to system levels is demonstrated. Through co‐design of a multi‐paradigm device, reconfigurable circuits, and adaptive system architecture/algorithms, the system enables seamless switching among spiking, non‐spiking, neuromorphic imaging (NI), and
Biyi Jiang   +7 more
wiley   +1 more source

LL-37, scrambled LL-37 and lysozyme induced bundle formation of Mg-F-actin at low and physiological (100 mM NaCl) ionic strength.

open access: yes, 2012
(A) Kinetics of LL-37-induced bundle formation: LL-37 (2–8 µM) was added to MgF-actin (2 µM) and bundle formation was followed as an increase in light scattering at 350 nm. Presented data are representative of three independent experiments. (B) Extent of
Andras Muhlrad (116643)   +3 more
core   +1 more source

A Critical Time Window of Neocortex Modulation for Remote Fear Memory in Rats and Humans

open access: yesAdvanced Science, EarlyView.
This study identifies a delayed consolidation window around 18 h after fear learning in the mPFC essential for remote fear memory. VTA dopaminergic input during this window sustains remote memory in rats, while non‐invasive stimulation of homologous human mPFC at the corresponding time selectively weakens remote but not recent fear memory, revealing a ...
Lu Cao   +19 more
wiley   +1 more source

TRAIP Mediates Alcohol‐Induced Liver Injury through Regulating β‐catenin Ubiquitin Degradation via Direct Interaction

open access: yesAdvanced Science, EarlyView.
This study reveals that NF‐κB1‐driven TRAIP upregulation in ALD correlates with disease severity. Mechanistically, TRAIP directly binds β‐catenin via its CC domain and promotes its K48‐linked ubiquitination and degradation, which is independent of the GSK3β/β‐TrCP pathway.
Zhan Wu   +13 more
wiley   +1 more source

Analysis of role of OMV-associated PrtV in LL-37 resistance.

open access: yes, 2015
(A) PrtV protein contributes to bacterial resistance against LL-37. V. cholerae O1 El Tor strain C6706 was grown in the presence of OMVs pre-incubated with a sub-lethal concentration (25 μg/ml) of the antimicrobial peptide LL-37.
Pramod K. Rompikuntal (361308)   +9 more
core   +1 more source

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