Protocol for in vitro phase separation of ARID3B proteins. [PDF]
Han W, Li X, Lin J, Pan Y.
europepmc +1 more source
Quantifying the Morphological Differences Between Fur Seals and Sea Lions
ABSTRACT The eared seals (family Otariidae) are divided into fur seals and sea lions, despite a lack of cladistic support for these groups. The division is primarily based on hair morphology, and it is unknown whether any other morphological signal differentiates these two groups.
Siobhan Pearson, James P. Rule
wiley +1 more source
Liquid-liquid phase separation enables chromatography-free purification and high-performance spidroin-amyloid hybrid silk fibers. [PDF]
Tufvesson K +9 more
europepmc +1 more source
Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg +18 more
wiley +1 more source
Phase separation in plants: mechanisms, functions, and a simplified workflow for investigation. [PDF]
Shen H +5 more
europepmc +1 more source
The Significance of cGAS‐STING Signaling in Response to Oncogenic Viruses
ABSTRACT The cyclic GMP‐AMP synthase (cGAS)‐stimulator of interferon genes (STING) signaling pathway, as a key DNA sensor, plays a significant role in the regulation of innate immune responses. This pathway can be activated by sensing abnormal DNA, and is of great significance for resisting the invasion of pathogenic microorganisms and maintaining ...
Limei Guo +4 more
wiley +1 more source
Rethinking bioinformatics in liquid-liquid phase separation: data resources, predictive models, and an event-centric perspective. [PDF]
Yuan ZL +9 more
europepmc +1 more source
CN Rail & TransX: Trucking's Effectiveness Complementing Rail's Efficiency
ABSTRACT This case study examines the strategic acquisition of TransX (TransX Group of Companies) by CN Rail (Canadian National Railway Company) on March 20, 2019. This acquisition aimed to enhance CN Rail's capabilities, particularly in the intermodal and temperature‐controlled segments.
Redwan Siddiqui, Fatih Yegul
wiley +1 more source
The Quest for the Associative Device for Hebbian‐Like LTP—The Accidental Participant
ABSTRACTIn 1985 Holger Wigström (now deceased) and I published a proposed scenario for the induction of hippocampal Hebbian‐like LTP to explain its input specificity and cooperativity. In this scenario LTP is induced by calcium influx through voltage‐dependent NMDA receptor channels co‐localized with the glutamate receptor channels (non‐NMDA) mediating
Bengt Gustafsson
wiley +1 more source
Epigenetic compartmentalization of mitotic chromosomes by phase-separation-driven repulsion between WDR5 and the chromosomal passenger complex. [PDF]
Wang Y +13 more
europepmc +1 more source

