Results 181 to 190 of about 15,588 (275)

Potent, Selective Pyrrolopyrimidine PDE11A4 Inhibitors with Improved Pharmaceutical Properties. [PDF]

ACS Med Chem Lett
Mahmood SU, Boddu RK, Eberhard J, Hoffman CS, Gordon J, Colussi D, Childers W, Amurrio E, Danaher M, Kelly MP, Rotella DP.   +10 more
europepmc   +1 more source

Economic burden of type 2 diabetes management in France according to clinical characteristics

Diabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 4019-4032, May 2026.
Abstract Aim We sought to investigate the treatment, medication patterns, and economic burden of type 2 diabetes (T2D) in France. Materials and Methods This was a descriptive retrospective cross‐sectional study of a representative sample of adults in the national healthcare system claims database in 2022.
Bruno Guerci, Christèle Blanc‐Bisson, Eric Vicaut, Gérard De Pouvourville, Bruno Detournay, Corinne Emery, Isabelle Bureau, Taos Ihaddadene‐Salzgeber, Fleur Levrat‐Guillen, Jean‐Pierre Riveline   +9 more
wiley   +1 more source

Phototriggered Morphological and Compositional Change of UGGAA Repeat RNA Foci by Photoswitchable RNA‐Binding Ligand

Angewandte Chemie, Volume 138, Issue 18, 27 April 2026.
We here developed a molecular tool for the optical control of UGGAA repeat RNA foci, a pathological hallmark of spinocerebellar ataxia type 31 (SCA31). The photoswitchable RNA‐binding ligand enabled reversible control of the RNA foci. UV irradiation induced the growth of the RNA foci, while subsequent visible light irradiation dissolved the structure ...
Yusuke Fujiwara, Tomonori Shibata, Chikara Dohno   +2 more
wiley   +2 more sources

The regulatory principles, physiological functions, and phase transition of biomolecular condensates. [PDF]

Front Cell Dev Biol
Li Q, Jiang Y, Chen Y.
europepmc   +1 more source

SARS‐CoV‐2 nucleocapsid protein variants have differential RNA chaperone activity

The FEBS Journal, Volume 293, Issue 9, Page 2579-2598, May 2026.
The SARS‐CoV‐2 nucleocapsid (N) protein is not only the specific viral RNA packaging protein, but also acts as an RNA chaperone, facilitating RNA folding. We show that it facilitates RNA annealing through its RBD–IDR2–CTD region, identifying it as a functional RNA chaperone.
Sabrina Babl, Julia M. Seidel, Fabian Kugler, Elisabeth Silberhorn, Anna Ludwig, Jonas Abel, Sophia Winklbauer, Niklas Schaub, Silvia Materna‐Reichelt, Kamran Honarnejad, Nataša Stojanović Gužvić, Gernot Längst   +11 more
wiley   +1 more source

Comprehensive analysis of liquid-liquid phase separation-related genes in osteosarcoma: implications for prognosis, immune infiltration and drug sensitivity. [PDF]

Transl Cancer Res
Han C, Zhao Z, Zhao X, Jiang J, Zhong T, Fang Y, Liang H, Song W.   +7 more
europepmc   +1 more source

How Does Credit Information Sharing Shape the Cyclicality of Bank Liquidity Creation?

Financial Review, Volume 61, Issue 2, Page 601-628, May 2026.
ABSTRACT We investigate the effect of credit information sharing in the banking sector on the fluctuations of bank liquidity creation over the business cycle. Using the Berger and Bouwman comprehensive measure of bank liquidity creation and data representing 354 banks from 40 developing countries between 2012 and 2020, we find that on‐ and off‐balance ...
Jeffrey Ighedosa, Victor Murinde, Tolulola Lawal   +2 more
wiley   +1 more source

Noncoding RNAs are indispensable architects and regulators of biomolecular condensates. [PDF]

Noncoding RNA Res
Chen S, Wang C, Hu J, Luo T, Li Q, Shen H.   +5 more
europepmc   +1 more source

Stress Granule‐Associated ZmCTU2 Confers Thermotolerance in Maize via Coordinated Regulation of Proteostasis and ROS Homeostasis

Plant Biotechnology Journal, Volume 24, Issue 5, Page 3371-3390, May 2026.
ABSTRACT The escalating global temperatures and intensifying heat stress events pose significant threats to maize productivity worldwide. Uncovering key thermotolerance genes and their functional mechanisms is thus critical for developing climate‐resilient crops.
Yufang Xu, Yudong Fan, Yulian Li, Yilin Zhang, Enpeng Liu, Ruiqi Li, Peipei Ma, Tao Li, Huiyong Zhang   +8 more
wiley   +1 more source

A global thermodynamic-kinetic model capturing the hallmarks of liquid-liquid phase separation and amyloid aggregation. [PDF]

Cell Rep Phys Sci
Bhandari K, Sun Y, Tang H, Ke PC, Ding F.   +4 more
europepmc   +1 more source