Results 111 to 120 of about 24,019 (217)

Patient and Disease-Specific Induced Pluripotent Stem Cells for Discovery of Personalized Cardiovascular Drugs and Therapeutics. [PDF]

, 2020
Human induced pluripotent stem cells (iPSCs) have emerged as an effective platform for regenerative therapy, disease modeling, and drug discovery.
Chandy, Mark, Paik, David T, Wu, Joseph C   +2 more
core  

LMNA Mutations, Skeletal Muscle Lipid Metabolism, and Insulin Resistance [PDF]

, 2010
Michael Boschmann, Stefan Engeli, Cédric Moro, A Luedtke, Frauke Adams, Kerstin Gorzelniak, Gabriele Rahn, Anja Mähler, Kerstin Dobberstein, Antje Krüger, Saskia Schmidt, Simone Spuler, Friedrich C. Luft, Steven R. Smith, Hartmut Schmidt, Jens Jordan   +15 more
openalex   +1 more source

Second-order cosmological perturbations. III. Produced by scalar-scalar coupling during radiation-dominated stage

, 2018
We study the 2nd-order scalar, vector and tensor metric perturbations in Robertson-Walker (RW) spacetime in synchronous coordinates during the radiation dominated (RD) stage. The dominant radiation is modeled by a relativistic fluid described by a stress
Wang, Bo, Zhang, Yang
core   +1 more source

Mandibuloacral Dysplasia Is Caused by a Mutation in LMNA-Encoding Lamin A/C [PDF]

, 2002
Giuseppe Novelli, Antoine Muchir, Federica Sangiuolo, A. Leclerc, Maria Rosaria D’Apice, Catherine Massart, Francesca Capon, Paolo Sbraccia, Massimo Federici, Renato Lauro, Cosimo Tudisco, R Pallotta, Gioacchino Scarano, Bruno Dallapiccola, Luciano Merlini, Gisèle Bonne   +15 more
openalex   +1 more source

Expression and localization of nuclear proteins in autosomal-dominant Emery-Dreifuss muscular dystrophy with LMNA R377H mutation [PDF]

, 2004
Beate Reichart, Ruth Klafke, Christine Karin Dreger, Eleonora Krüger, Isabell Motsch, Andrea Ewald, Jochen Schäfer, Heinz Reichmann, Clemens R. Müller, Marie‐Christine Dabauvalle   +9 more
openalex   +1 more source

Genotype‐phenotype analysis of LMNA ‐related diseases predicts phenotype‐selective alterations in lamin phosphorylation [PDF]

, 2020
Eric W. Lin, Graham F. Brady, Raymond Kwan, Alexey I. Nesvizhskii, M. Bishr Omary   +4 more
openalex   +1 more source

Perinuclear organelle trauma at the nexus of cardiomyopathy pathogenesis arising from loss of function LMNA mutation

Nucleus
Over the past 25 years, nuclear envelope (NE) perturbations have been reported in various experimental models with mutations in the LMNA gene. Although the hypothesis that NE perturbations from LMNA mutations are a fundamental feature of striated muscle ...
Jason C. Choi
doaj   +1 more source

A conserved splicing mechanism of the LMNA gene controls premature aging [PDF]

, 2011
Isabel C. López‐Mejía, Valentin Vautrot, Marion de Toledo, Isabelle Behm‐Ansmant, Cyril F. Bourgeois, Claire Navarro, Fernando G. Osorio, José M.P. Freije, James Stévenin, Annachiara De Sandre‐Giovannoli, Carlos López-Otı́n, Nicolas Lévy, Christiane Branlant, Jamal Tazi   +13 more
openalex   +1 more source

Spin rotation for ballistic electron transmission induced by spin-orbit interaction

, 2002
We study spin dependent electron transmission through one- and two-dimensional curved waveguides and quantum dots with account of spin-orbit interaction.
A. Voskoboynikov, A. Voskoboynikov, Almas F. Sadreev, C.-M. Hu, E. Šimánek, E.N. Bulgakov, Evgeny N. Bulgakov, F. Mireles, K.N. Pichugin, L.I. Magarill, L.I. Magarill, P. Exner, S. Datta, T.-Z. Qian, Yu.A. Bychkov   +14 more
core   +1 more source

Posttranslational Modifications of Lamin A/C and Cardiac Aging: A Short Review

Journal of the Practice of Cardiovascular Sciences
Cardiac aging is considered as natural and age-related changes in the heart, which can lead to a decline in heart function. Cardiac aging increases the risk of heart failure, atrial fibrillation, and other cardiovascular complications.
Vikas Tiwari, Samhita Chakraborty, Sanjay K. Banerjee   +2 more
doaj   +1 more source