Results 161 to 170 of about 48,734 (209)

ZFP36L1 promotes non‐small cell lung cancer progression under hypoxia by modulating CXCL9:SPP1 polarity: A single‐cell transcriptomic study

Clinical and Translational Medicine, Volume 16, Issue 4, April 2026.
1. Under hypoxia, downregulating the CXCL9:SPP1 ratio in macrophages promoted malignant progression of non‐small cell lung cancer (NSCLC). 2. Transcriptional factor ZFP36L1 modulated the CXCL9:SPP1 macrophage polarity. 3. ZFP36L1‐driven SPP1+ macrophages could accelerate NSCLC progression by binding to CD44 on the tumour cell surface.
Lijie Wang, Biao Chen, Jinxian He, Chengbin Lin, Weiyu Shen, Wang Lv, Luming Wang, Jian Hu   +7 more
wiley   +1 more source

LncRNA miR17HG promotes tumor progression through AXIN2 by sponging miR-144-3p in bladder cancer. [PDF]

World J Surg Oncol
Chen Q, Wu K, Cai B, Yu X, Zhang X, Yang Y.   +5 more
europepmc   +1 more source

The 5‐Methylcytosine RNA Modification in Hepatitis B Virus‐Negative Hepatocellular Carcinoma: Insights From Long‐Read Nanopore Sequencing

Molecular Carcinogenesis, Volume 65, Issue 4, Page 397-406, April 2026.
ABSTRACT 5‐Methylcytosine (m5C) RNA modification contributes to tumor initiation and progression. However, its transcriptome‐wide distribution patterns and biological implications in hepatitis B virus (HBV)‐negative hepatocellular carcinoma (HCC) remain poorly understood.
Tianhan Sun, Liying Zhou, XiaoQing Li, Ryan Xiao, Gaoyuan Sun, Lili Zhang, Yifei Li, Wei Huang, Yayu Li, Lu Kuai, Xuanmei Luo, Hongyuan Cui, Meng Chen   +12 more
wiley   +1 more source

Comprehensive <i>Schistosoma mansoni</i> Hierarchical Transcriptome Assembly Points to Novel lncRNAs Associated with Sexual Dimorphism. [PDF]

Noncoding RNA
Freire CF, Souza-Lopes T, Amaral MS, Tahira AC, Verjovski-Almeida S.   +4 more
europepmc   +1 more source

The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases

MedComm, Volume 7, Issue 4, April 2026.
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi, Shahin Ramazi, Mona Darvazi, Sepideh Yoosefi, Melika Abbasi, Shirin Farsad   +5 more
wiley   +1 more source

Potential biomarkers and regulatory pathways associated with arteriovenous fistula stenosis in end-stage renal disease: an analysis based on transcriptomic profiling. [PDF]

BMC Nephrol
Zhao M, An Y, Li W, Yang W, Chen W, Lu H.   +5 more
europepmc   +1 more source

Sulforaphane Synergizes With PD‐1 Blockade Through Activating CD8+ T Cells in Non–Small Cell Lung Cancer: Preclinical and Clinical Investigations

MedComm, Volume 7, Issue 4, April 2026.
SFN sensitizes PD‐1 blockade therapy in preclinical and clinical investigations, with no side effects. SFN elevates the antitumor response in peripheral and tumor microenvironment. ABSTRACT Anti‐PD‐1/PD‐L1 therapy has achieved promising success across several tumor types; however, its efficacy is still far from satisfactory in non–small cell lung ...
Jieyao Li, Jinyan Liu, Zheng Wang, Ming Zhao, Mingming You, Ziyi Fu, Caijuan Guo, Tengyue Zhang, Shasha Liu, Dongli Yue, Shuangning Yang, Yixin Li, Qun Gao, Yanfen Liu, Jianmin Huang, Liping Wang, Yi Zhang   +16 more
wiley   +1 more source

Decoding the lncRNA World: Comprehensive Approaches to lncRNA Structure and Interactome Studies. [PDF]

Cells
Oh M, Lee BL, Somarowthu S.
europepmc   +1 more source

Expression and Clinical Significance of the Long Non‐Coding RNA OIP5‐AS1 in Alcohol Use Disorder

Addiction Biology, Volume 31, Issue 4, April 2026.
Plasma OIP5‐AS1 is significantly elevated in alcohol use disorder. Higher OIP5‐AS1 expression is associated with lower body mass index and shows good diagnostic performance for distinguishing alcohol use disorder from healthy controls (AUC = 0.9091, sensitivity = 100%, specificity = 75%).
Meng ya Zhu, Jian Wang, Jia Jia Song, Yue Wang, Bo Zhang   +4 more
wiley   +1 more source

METTL7B-stabilized lncRNA-MIR22HG to drive p53-mediated neuronal apoptosis via the ubiquitinating JARID2 in cerebral ischemia/reperfusion injury. [PDF]

Cell Biol Toxicol
Zhang H, Li M, Wu Y, Sun X.
europepmc   +1 more source