Results 41 to 50 of about 6,544,784 (149)

Structural Modifications and Novel Protein-Binding Sites in Pre-miR-675—Explaining Its Regulatory Mechanism in Carcinogenesis

open access: yesNon-Coding RNA, 2023
Pre-miR-675 is a microRNA expressed from the exon 1 of H19 long noncoding RNA, and the atypical expression of pre-miR-675 has been linked with several diseases and disorders including cancer. To execute its function inside the cell, pre-miR-675 is folded
Abhishek Dey
doaj   +1 more source

DataSheet_1_Projection-Based Neighborhood Non-Negative Matrix Factorization for lncRNA-Protein Interaction Prediction.zip

open access: yes, 2019
Many long ncRNAs (lncRNA) make their effort by interacting with the corresponding RNA-binding proteins, and identifying the interactions between lncRNAs and proteins is important to understand the functions of lncRNA. Compared with the time-consuming and
Tingting He (297525)   +2 more
core   +1 more source

LPI-KTASLP: Prediction of LncRNA-Protein Interaction by Semi-Supervised Link Learning With Multivariate Information

open access: yesIEEE Access, 2019
Long non-coding RNA, also known as lncRNA, is a series of single-stranded polynucleotides (no less than 200 nucleotides each), consisting of non-protein coding transcripts.
Cong Shen   +4 more
doaj   +1 more source

Table_1_Projection-Based Neighborhood Non-Negative Matrix Factorization for lncRNA-Protein Interaction Prediction.xlsx

open access: yes, 2019
Many long ncRNAs (lncRNA) make their effort by interacting with the corresponding RNA-binding proteins, and identifying the interactions between lncRNAs and proteins is important to understand the functions of lncRNA. Compared with the time-consuming and
Tingting He (297525)   +2 more
core   +1 more source

LncRNA-TBP mediates TATA-binding protein recruitment to regulate myogenesis and induce slow-twitch myofibers

open access: yesCell Communication and Signaling, 2023
Background Skeletal muscle is comprised of heterogeneous myofibers that differ in their physiological and metabolic parameters. Of these, slow-twitch (type I; oxidative) myofibers have more myoglobin, more mitochondria, and higher activity of oxidative ...
Manting Ma   +7 more
doaj   +1 more source

A machine learning framework that integrates multi-omics data predicts cancer-related LncRNAs

open access: yesBMC Bioinformatics, 2021
Background LncRNAs (Long non-coding RNAs) are a type of non-coding RNA molecule with transcript length longer than 200 nucleotides. LncRNA has been novel candidate biomarkers in cancer diagnosis and prognosis.
Lin Yuan, Jing Zhao, Tao Sun, Zhen Shen
doaj   +1 more source

PTOMSM: A modified version of Topological Overlap Measure used for predicting Protein-Protein Interaction Network [PDF]

open access: yes, 2009
A variety of methods are developed to integrating diverse biological data to predict novel interaction relationship between proteins. However, traditional integration can only generate protein interaction pairs within existing relationships.
Xun Huang
core   +1 more source

Chapter4_Resis_and_Suscep_DE-lncRNA-DEmRNA-PPI network_and BiNGO_results

open access: yes, 2023
Chapter4_Resis_and_Suscep_DE-lncRNA-DEmRNA-PPI network_and ...
Aiswarya Jayaprakash (13828057)
core   +1 more source

Allo-network drugs: Extension of the allosteric drug concept to protein-protein interaction and signaling networks [PDF]

open access: yes, 2013
Allosteric drugs are usually more specific and have fewer side effects than orthosteric drugs targeting the same protein. Here, we overview the current knowledge on allosteric signal transmission from the network point of view, and show that most ...
Csermely, Péter   +3 more
core   +2 more sources

PLAIDOH: a novel method for functional prediction of long non-coding RNAs identifies cancer-specific LncRNA activities

open access: yesBMC Genomics, 2019
Background Long non-coding RNAs (lncRNAs) exhibit remarkable cell-type specificity and disease association. LncRNA’s functional versatility includes epigenetic modification, nuclear domain organization, transcriptional control, regulation of RNA splicing
Sarah C. Pyfrom   +2 more
doaj   +1 more source

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