Results 31 to 40 of about 6,544,784 (149)

Gene Ontology-based function prediction of long non-coding RNAs using bi-random walk

BMC Medical Genomics, 2018
Background With the development of sequencing technology, more and more long non-coding RNAs (lncRNAs) have been identified. Some lncRNAs have been confirmed that they play an important role in the process of development through the dosage compensation ...
Jingpu Zhang, shuai Zou, Lei Deng
doaj   +1 more source

Long Noncoding RNA MEG3-205/Let-7a/MyD88 Axis Promotes Renal Inflammation and Fibrosis in Diabetic Nephropathy

Kidney Diseases, 2022
Aim: The aim of this study was to investigate the role and mechanism of long noncoding RNA (lncRNA) maternally expressed gene 3 (MEG3)-205 in renal inflammation and fibrosis in diabetic nephropathy (DN). Materials and Methods: lncRNA microarray profiling
Qimei Luo, Xi Xia, Qingqing Luo, Yue Qiu, Lan Dong, Chen Zhao, Fenfen Peng, Jing Yu, Fengxian Huang, Feng He   +9 more
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Evolutionarily conserved herpesviral protein interaction networks. [PDF]

, 2009
Herpesviruses constitute a family of large DNA viruses widely spread in vertebrates and causing a variety of different diseases. They possess dsDNA genomes ranging from 120 to 240 kbp encoding between 70 to 170 open reading frames. We previously reported
Bandyopadhyay, Sourav, Baiker Armin, Brunn, Albrecht von, Dong, Yu-An, Silpa Suthram, Haas, Jürgen, Dietlind Rose, von Brunn, Albrecht, Rutenberg Christiane, Ralf Zimmer, Bailer Susanne M., Schmidt, Tina, Stellberger Thorsten, Rose, Dietlind, Haas Jürgen, Titz Björn, Zimmer, Ralf, Christine Zeretzke, Mareike Uhlmann, Seesandra V Rajagopala, Manfred Koegl, Boulet Hélène, Koegl, Manfred, Susanne M Bailer, Trey Ideker, Baiker, Armin, Fossum, Even, Zeretzke, Christine, Peter Uetz, Schmidt Tina, Koegl Manfred, Thorsten Stellberger, Hélène Boulet, Kraus Theo, Armin Baiker, Tina Schmidt, Ideker, Trey, Koszinowski, Ulrich, Sourav Bandyopadhyay, Suthram Silpa, Björn Titz, Boulet, Hélène, Koszinowski Ulrich, Rajagopala, Seesandra V., Caroline C Friedel, Bailer, Susanne M, Rajagopala, Seesandra V, Dong Yu-An, Even Fossum, Bandyopadhyay Sourav, Bailer, Susanne M., Uhlmann, Mareike, Haas, Jürgen G., Ulrich Koszinowski, Uhlmann Mareike, Uetz Peter, Zimmer Ralf, Christiane Rutenberg, Friedel, Caroline C., Friedel, Caroline C, Titz, Björn, Koszinowski, Ulrich H., Rajagopala Seesandra V., Titz, Bjoern, Haas, Juergen, Ideker Trey, Albrecht von Brunn, Suthram, Silpa, Zeretzke Christine, Rutenberg, Christiane, Kraus, Theo, Jürgen Haas, Friedel Caroline C., Stellberger, Thorsten, Theo Kraus, Yu-An Dong, Rose Dietlind, Fossum Even, Uetz, Peter, von Brunn Albrecht   +79 more
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Sequence Motifs in MADS Transcription Factors Responsible for Specificity and Diversification of Protein-Protein Interaction [PDF]

, 2010
Protein sequences encompass tertiary structures and contain information about specific molecular interactions, which in turn determine biological functions of proteins.
Angenent, G.C., Martijn Fiers, Roeland C H J van Ham, Roeland C. H. J. van Ham, Morabito Giuseppa, Ham, R.C.H.J., van, Aalt D J van Dijk, Angenent Gerco C., Immink, R.G.H., van Dijk, A.D.J., Richard G H Immink, van Dijk Aalt D. J., Morabito, G., van Ham Roeland C. H. J., Dijk, A.D.J., van, Fiers, M.A., Richard G. H. Immink, Giuseppa Morabito, van Ham, R.C.H.J., Aalt D. J. van Dijk, Immink Richard G. H., Gerco C Angenent, Gerco C. Angenent, Fiers Martijn   +23 more
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A web-based protein interaction network visualizer [PDF]

, 2014
Background Interaction between proteins is one of the most important mechanisms in the execution of cellular functions. The study of these interactions has provided insight into the functioning of an organism’s processes.
Holifidy A Rapanoël, Mazandu, Gaston K, Ayton Meintjes, Gustavo A Salazar, Salazar, Gustavo A, Gaston K Mazandu, Rapanoël, Holifidy A, Akinola, Richard O, Meintjes, Ayton, Richard O Akinola, Mulder, Nicola J, Nicola J Mulder   +11 more
core   +1 more source

Altered long noncoding RNA profile after intracerebral hemorrhage

Annals of Clinical and Translational Neurology, 2019
Objective We investigated the expression pattern of long noncoding RNAs (lncRNA) and messenger RNAs (mRNA) from two different intracerebral hemorrhage (ICH) rat models, and performed gene ontology and gene/protein interaction analyses.
Jeong‐Min Kim, Jangsup Moon, Jung‐Suk Yu, Dong‐Kyu Park, Soon‐Tae Lee, Keun‐Hwa Jung, Kon Chu   +6 more
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Integrated analyses of long noncoding RNAs and mRNAs in the progression of breast cancer

Journal of International Medical Research, 2021
Objective The objective was to explore the expression and potential functions of long noncoding RNA (lncRNA) and mRNAs in human breast cancer (BC). Methods Differentially expressed lncRNAs and mRNAs were identified and annotated in BC tissues by using ...
Jingyun Guo, Huining Lian, Minfeng Liu, Jianyu Dong, Zhaoze Guo, Jinlamao Yang, Changsheng Ye   +6 more
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Studying protein-protein interactions using peptide arrays [PDF]

, 2010
Screening of arrays and libraries of compounds is well-established as a high-throughput method for detecting and analyzing interactions in both biological and chemical systems. Arrays and libraries can be composed from various types of molecules, ranging
Rito, T., Rudiger, S.G.D., Sub Cellular Protein Chemistry, Rotem-Bamberger, S., Katz, C., Friedler, A., Levy-Beladev, L., Cellular Protein Chemistry   +7 more
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Improving the resolution of interaction maps: A middleground between high-resolution complexes and genome-wide interactomes [PDF]

, 2013
Protein-protein interactions are ubiquitous in Biology and therefore central to understand living organisms. In recent years, large-scale studies have been undertaken to describe, at least partially, protein-protein interaction maps or interactomes for a
Mora, Joan Segura
core   +6 more sources

The binding of lncRNA RP11-732M18.3 with 14-3-3 β/α accelerates p21 degradation and promotes glioma growthResearch in context

EBioMedicine, 2019
Background: Long noncoding RNAs (lncRNAs) have been identified as regulators of a number of developmental and tumorigenic processes. However, the functions of most lncRNAs in glioma remain unknown and the mechanisms governing the proliferation of tumor ...
Chun-Min Kang, Huan-Lan Bai, Xue-Heng Li, Rui-Ying Huang, Jing-Jing Zhao, Xiao-Yan Dai, Lei Zheng, Yu-Rong Qiu, Yan-Wei Hu, Qian Wang   +9 more
doaj   +1 more source