Results 11 to 20 of about 65,052 (248)

LPIH2V: LncRNA-protein interactions prediction using HIN2Vec based on heterogeneous networks model

Frontiers in Genetics, 2023
LncRNA-protein interaction plays an important role in the development and treatment of many human diseases. As the experimental approaches to determine lncRNA–protein interactions are expensive and time-consuming, considering that there are few ...
Meng-Meng Wei, Chang-Qing Yu, Li-Ping Li, Li-Ping Li, Zhu-Hong You, Zhong-Hao Ren, Yong-Jian Guan, Xin-Fei Wang, Yue-Chao Li   +8 more
doaj   +1 more source

LncRNA expression profile in human malignant embryonic rhabdomyosarcoma cell line infected with Coxsackie virus group B type 5 [PDF]

Jichu yixue yu linchuang, 2022
Objective To explore the molecular mechanism of the interaction between Coxsackie virus group B type 5 (CVB5) and the host, The long non-coding RNA(lncRNA) expression profile in human malignant embryonic rhabdomyosarcoma cell line (RD) infected by CVB5 ...
TENG Pei-ying, LI Jing, SHI Yu-lu, YANG Fan, OU Xia, CHEN Wei
doaj   +1 more source

SGII: Systematic Identification of Essential lncRNAs in Mouse and Human Genome With lncRNA-Protein-Protein Heterogeneous Interaction Network

Frontiers in Genetics, 2022
Long noncoding RNAs (lncRNAs) play important roles in a variety of biological processes. Knocking out or knocking down some lncRNA genes can lead to death or infertility. These lncRNAs are called essential lncRNAs.
Xiao-Hong Xin, Ying-Ying Zhang, Chu-Qiao Gao, Hui Min, Likun Wang, Pu-Feng Du   +5 more
doaj   +1 more source

Predicting lncRNA-protein interactions with bipartite graph embedding and deep graph neural networks

Frontiers in Genetics, 2023
Background: Long non-coding RNAs (lncRNAs) play crucial roles in numerous biological processes. Investigation of the lncRNA-protein interaction contributes to discovering the undetected molecular functions of lncRNAs.
Yuzhou Ma, Han Zhang, Chen Jin, Chuanze Kang   +3 more
doaj   +1 more source

Long noncoding RNA HOTAIR interacts with Y-Box Protein-1 (YBX1) to regulate cell proliferation

Life Science Alliance, 2021
The authors determined that HOTAIR specifically bind to YBX1 and promote its nuclear translocation, and then regulating cell proliferation by stimulating the PI3K/Akt and ERK/RSK signaling pathways. HOTAIR is a long noncoding RNA (lncRNA) which serves as
Siting Li, Qian Xiong, Minghai Chen, Bing Wang, Xue Yang, Mingkun Yang, Qiang Wang, Zongqiang Cui, Feng Ge   +8 more
doaj   +1 more source

Predicting lncRNA–Protein Interactions With miRNAs as Mediators in a Heterogeneous Network Model

Frontiers in Genetics, 2020
Long non-coding RNAs (lncRNAs) play important roles in various biological processes, where lncRNA–protein interactions are usually involved. Therefore, identifying lncRNA–protein interactions is of great significance to understand the molecular functions
Yuan-Ke Zhou, Zi-Ang Shen, Han Yu, Tao Luo, Yang Gao, Pu-Feng Du   +5 more
doaj   +1 more source

The Challenges and Opportunities of lncRNAs in Ovarian Cancer Research and Clinical Use [PDF]

, 2020
[Abstract] Ovarian cancer is one of the most lethal gynecological malignancies worldwide because it tends to be detected late, when the disease has already spread, and prognosis is poor.
Barreiro-Alonso, Aida, Cerdán, María Esperanza, Lamas, Mónica, Quindós-Varela, María, Rodríguez-Belmonte, Esther, Salamini-Montemurri, Martín, Vizoso-Vázquez, Ángel   +6 more
core   +1 more source

Interaction and cross-talk between non-coding RNAs. [PDF]

, 2017
Non-coding RNA (ncRNA) has been shown to regulate diverse cellular processes and functions through controlling gene expression. Long non-coding RNAs (lncRNAs) act as a competing endogenous RNAs (ceRNAs) where microRNAs (miRNAs) and lncRNAs regulate each ...
Dahiya, Rajvir, Imai-Sumida, Mitsuho, Tanaka, Yuichiro, Yamamura, Soichiro   +3 more
core   +2 more sources

Integrative analyses of transcriptome sequencing identify novel functional lncRNAs in esophageal squamous cell carcinoma. [PDF]

, 2017
Long non-coding RNAs (lncRNAs) have a critical role in cancer initiation and progression, and thus may mediate oncogenic or tumor suppressing effects, as well as be a new class of cancer therapeutic targets. We performed high-throughput sequencing of RNA
Ai, B, Bai, X-F, Cao, H-H, Feng, C-C, He, J-Z, Huang, G-W, Koeffler, HP, Lei, F, Li, C-Q, Li, E-M, Li, M, Li, S, Li, X, Li, X-C, Liao, L-D, Lin, D-C, Liu, Y-J, Shen, J-H, Tang, Z-D, Wang, L-D, Wang, M-R, Wang, Q-Y, Wang, S-H, Wu, B-L, Wu, J-Y, Wu, Z-Y, Xu, L-Y, Xu, Y-J, Xue, Y-J, Zhang, J, Zhao, J-M, Zheng, C-P, Zhu, Y   +32 more
core   +1 more source

The Nefarious Nexus of Noncoding RNAs in Cancer [PDF]

, 2018
The past decade has witnessed enormous progress, which has seen the noncoding RNAs (ncRNAs) turn from the so called dark matter RNA to critical functional molecules, influencing most physiological processes in development and disease contexts.
Anastasiadou, Eleni, Faggioni, Alberto, J Slack, Frank, Trivedi, Pankaj   +3 more
core   +1 more source