Results 11 to 20 of about 6,544,784 (149)
The Interaction of lncRNA-HEIH and lncRNA-HULC with HBXIP in Hepatitis B Patients
Gastroenterology Research and Practice, 2018 Hepatitis B virus (HBV) infection is a major risk factor for the development of hepatic cirrhosis (HC) and hepatocellular carcinoma (HCC), which are associated with very high morbidity and mortality rates worldwide.
Lingjuan Ruan +7 more
doaj +2 more sources
Frontiers in Genetics, 2022 Long noncoding RNAs (lncRNAs) play important roles in a variety of biological processes. Knocking out or knocking down some lncRNA genes can lead to death or infertility. These lncRNAs are called essential lncRNAs.
Xiao-Hong Xin +5 more
doaj +1 more source
Predicting lncRNA-protein interactions with bipartite graph embedding and deep graph neural networks
Frontiers in Genetics, 2023 Background: Long non-coding RNAs (lncRNAs) play crucial roles in numerous biological processes. Investigation of the lncRNA-protein interaction contributes to discovering the undetected molecular functions of lncRNAs.
Yuzhou Ma +3 more
doaj +1 more source
Long noncoding RNA HOTAIR interacts with Y-Box Protein-1 (YBX1) to regulate cell proliferation
Life Science Alliance, 2021 The authors determined that HOTAIR specifically bind to YBX1 and promote its nuclear translocation, and then regulating cell proliferation by stimulating the PI3K/Akt and ERK/RSK signaling pathways. HOTAIR is a long noncoding RNA (lncRNA) which serves as
Siting Li +8 more
doaj +1 more source
Predicting lncRNA–Protein Interactions With miRNAs as Mediators in a Heterogeneous Network Model
Frontiers in Genetics, 2020 Long non-coding RNAs (lncRNAs) play important roles in various biological processes, where lncRNA–protein interactions are usually involved. Therefore, identifying lncRNA–protein interactions is of great significance to understand the molecular functions
Yuan-Ke Zhou +5 more
doaj +1 more source
Fitting a geometric graph to a protein-protein interaction network [PDF]
, 2008 Finding a good network null model for protein-protein interaction (PPI) networks is a fundamental issue. Such a model would provide insights into the interplay between network structure and biological function as well as into evolution.
Higham, Desmond J. +2 more
core +4 more sources
Revealing protein-lncRNA interaction [PDF]
, 2015 Long non-coding RNAs (lncRNAs) are associated to a plethora of cellular functions, most of which require the interaction with one or more RNA-binding proteins (RBPs); similarly, RBPs are often able to bind a large number of different RNAs.
Helmer Citterich, Manuela +5 more
core +1 more source
Assessing recent selection and functionality at long noncoding RNA loci in the mouse genome [PDF]
, 2015 This work was supported by the Biotechnology and Biological Sciences Research Council and The Wellcome Trust. A.N. was supported by the Swiss National Science Foundation (Grant: PZ00P3_142636). H.K. was supported by the European Research Council Starting
Ness, Rob W +19 more
core +1 more source
, 2022 Long noncoding RNAs (lncRNAs) play important roles in a variety of biological processes. Knocking out or knocking down some lncRNA genes can lead to death or infertility. These lncRNAs are called essential lncRNAs.
Pu-Feng Du (8158638) +5 more
core +1 more source
Prediction of protein-protein interaction types using association rule based classification [PDF]
, 2009 This article has been made available through the Brunel Open Access Publishing Fund - Copyright @ 2009 Park et alBackground: Protein-protein interactions (PPI) can be classified according to their characteristics into, for example obligate or transient ...
José A Reyes +14 more
core +1 more source