Results 51 to 60 of about 64,353 (185)
The how and why of lncRNA function: An innate immune perspective. [PDF]
, 2020 Next-generation sequencing has provided a more complete picture of the composition of the human transcriptome indicating that much of the "blueprint" is a vastness of poorly understood non-protein-coding transcripts.
Carpenter, Susan +2 more
core
EBioMedicine, 2019 Background: Long noncoding RNAs (lncRNAs) have been identified as regulators of a number of developmental and tumorigenic processes. However, the functions of most lncRNAs in glioma remain unknown and the mechanisms governing the proliferation of tumor ...
Chun-Min Kang +9 more
doaj +1 more source
Non-Coding RNA, 2023 Pre-miR-675 is a microRNA expressed from the exon 1 of H19 long noncoding RNA, and the atypical expression of pre-miR-675 has been linked with several diseases and disorders including cancer. To execute its function inside the cell, pre-miR-675 is folded
Abhishek Dey
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Long Non-Coding RNAs: New Players in Hematopoiesis and Leukemia [PDF]
, 2015 Long non-coding RNAs (lncRNAs) are important regulators of gene expression that influence almost every step in the life cycle of genes, from transcription to mRNA splicing, RNA decay, and translation.
Ballarino, Monica +2 more
core +2 more sources
Cell Communication and Signaling, 2023 Background Skeletal muscle is comprised of heterogeneous myofibers that differ in their physiological and metabolic parameters. Of these, slow-twitch (type I; oxidative) myofibers have more myoglobin, more mitochondria, and higher activity of oxidative ...
Manting Ma +7 more
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The effect of microRNA-375 overexpression, an inhibitor of Helicobacter pylori-induced carcinogenesis, on lncRNA SOX2OT [PDF]
, 2016 Background: Helicobacter pylori is a major human pathogenic bacterium in gastric mucosa. Although the association between gastric cancer and H. pylori has been well-established, the molecular mechanisms underlying H.
Aleyasin, S.A. +4 more
core +1 more source
IEEE Access, 2019 Long non-coding RNA, also known as lncRNA, is a series of single-stranded polynucleotides (no less than 200 nucleotides each), consisting of non-protein coding transcripts.
Cong Shen +4 more
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A machine learning framework that integrates multi-omics data predicts cancer-related LncRNAs
BMC Bioinformatics, 2021 Background LncRNAs (Long non-coding RNAs) are a type of non-coding RNA molecule with transcript length longer than 200 nucleotides. LncRNA has been novel candidate biomarkers in cancer diagnosis and prognosis.
Lin Yuan, Jing Zhao, Tao Sun, Zhen Shen
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Single cell analysis reveals the involvement of the long non-coding RNA Pvt1 in the modulation of muscle atrophy and mitochondrial network [PDF]
, 2019 Long non-coding RNAs (lncRNAs) are emerging as important players in the regulation of several aspects of cellular biology. For a better comprehension of their function, it is fundamental to determine their tissue or cell specificity and to identify their
Alessio, Enrico +13 more
core +1 more source
BMC Genomics, 2019 Background Long non-coding RNAs (lncRNAs) exhibit remarkable cell-type specificity and disease association. LncRNA’s functional versatility includes epigenetic modification, nuclear domain organization, transcriptional control, regulation of RNA splicing
Sarah C. Pyfrom +2 more
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