Results 121 to 130 of about 167,789 (348)
Epigenetics, 2018 Long noncoding RNAs (lncRNAs) are critical regulators of cell biology whose alteration can lead to the development of diseases such as cancer. The potential role of lncRNAs and their epigenetic regulation in response to platinum treatment are largely ...
Olga Vera +5 more
doaj +1 more source
Multi‐Tissue Omics Analysis Uncovers Translational Regulation Underlying Complex Traits in Pigs
Advanced Science, EarlyView.Integrated multi‐omics across pig breeds and tissues reveals key principles of post‐transcriptional translational regulation and their contribution to trait formation. A gene network framework integrating transcriptomic and translatomic data is developed and applied to elucidate the genetic basis of meat production, offering new insights into mammalian
Chao Wang +13 more
wiley +1 more source
Epigenetics, 2018 Infants born preterm are at increased risk of multiple morbidities and mortality. Why some women deliver preterm remains poorly understood. Prior studies have shown that cervical microRNA expression and DNA methylation are associated with the length of ...
Heather H. Burris +10 more
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Antisense oligonucleotides targeting lncRNA AC104041.1 induces antitumor activity through Wnt2B/β-catenin pathway in head and neck squamous cell carcinomas [PDF]
, 2020 Mengwei Li +12 more
openalex +1 more source
LncRNA SNHG6/miR-125b-5p/BMPR1B Axis: A New Therapeutic Target for Triple-Negative Breast Cancer [PDF]
, 2021 Yufei Lv +9 more
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LncRNA-encoded polypeptide ASRPS inhibits triple-negative breast cancer angiogenesis
Journal of Experimental Medicine, 2019 In this study, Wang et al. demonstrate that lncRNA-encoded polypeptide ASRPS is down-regulated in TNBC. ASRPS regulates angiogenesis and may serve as a novel prognostic marker and therapeutic target for TNBC.
Yirong Wang +12 more
semanticscholar +1 more source
Guidelines for the Anti‐Obesity Assays of Food Bioactives in Caenorhabditis elegans
AgriFood: Journal of Agricultural Products for Food, EarlyView.This Guideline uses Caenorhabditis elegans as a model organism to systematically explain and summarize the research strategies and experimental methods for the anti‐obesity effects of food bioactives. ABSTRACT The obesity has become a global public health problem and is closely related to a variety of chronic diseases.
Rui Lu
wiley +1 more source
Cancer Management and Research, 2020 Suzhen Yan,1,* Lutao Du,1,* Xiumei Jiang,2 Weili Duan,1 Juan Li,1 Yujiao Xie,1 Yao Zhan,1 Shujun Zhang,1 Lili Wang,2 Shuhai Li,3 Chuanxin Wang1,4 1Department of Clinical Laboratory, The Second Hospital of Shandong University, Jinan, Shandong Province ...
Yan S +10 more
doaj
The Regulatory Roles of Long-non-Coding RNAs in Chemotherapy-Resistant Metastatic Breast Cancer [PDF]
Journal of Advanced Biomedical Sciences, 2020 Currently, breast cancer is the most prevalent malignancy worldwide, with the largest prevalence and mortality among women. The invasion and metastasis are the main causes of death from malignancies. However, the main mechanism of invasion and metastasis
Saeid Ghorbian +2 more
doaj
LncRNA H19 initiates microglial pyroptosis and neuronal death in retinal ischemia/reperfusion injury
Cell Death and Differentiation, 2019 Ischemia-reperfusion (I/R) is a common pathology when the blood supply to an organ was disrupted and then restored. During the reperfusion process, inflammation and tissue injury were triggered, which were mediated by immunocytes and cytokines.
P. Wan +9 more
semanticscholar +1 more source